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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLV
HFLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGGDLTPLAHMVLCLQGRGDF
LDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALS
DLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNA
VTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQV
TATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKL
VQALREQFPPLETDRPLGQEIAALATHLLQQSPV

The query sequence (length=514) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2o7d:A 515 514 0.9981 0.9961 0.9981 0.0 2o7d:D, 2o7d:B, 2o7d:C, 2o7d:E, 2o7d:H, 2o7d:F, 2o7d:G, 2o7e:A, 2o7e:D, 2o7e:B, 2o7e:C, 2o7e:E, 2o7e:H, 2o7e:F, 2o7e:G
2 3kdz:A 527 494 0.3911 0.3814 0.4069 3.30e-98 3kdz:B, 2qve:A, 2qve:B, 2rjr:A, 2rjs:A, 2rjs:B
3 3unv:A 514 511 0.3366 0.3366 0.3386 1.61e-89 3unv:B
4 1gkm:A 507 495 0.3560 0.3609 0.3697 8.59e-73
5 5ltm:B 537 476 0.3074 0.2942 0.3319 1.48e-63 5ltm:A
6 6f6t:B 677 487 0.2860 0.2171 0.3018 1.18e-50 6f6t:A, 6hqf:A, 6hqf:B
7 4c5s:C 642 447 0.2665 0.2134 0.3065 3.87e-46 4c5r:A, 4c5r:B, 4c5r:C, 4c5r:D, 4c5s:A, 4c5s:B, 4c5s:D
8 6rgs:B 626 409 0.2451 0.2013 0.3081 5.38e-45
9 9eq5:A 511 472 0.2646 0.2661 0.2881 1.16e-41 9eq5:D, 9eq5:B, 9eq5:C
10 6s7q:A 497 508 0.2549 0.2636 0.2579 6.64e-33 6s7q:D, 6s7q:B, 6s7q:C, 6s7q:E, 6s7q:H, 6s7q:F, 6s7q:G
11 2zfn:A 376 107 0.0623 0.0851 0.2991 1.3 3cz7:A, 3qm0:A
12 3q33:A 394 107 0.0623 0.0812 0.2991 1.3 3q35:A
13 1h6d:A 383 52 0.0350 0.0470 0.3462 6.0 1evj:A, 1evj:B, 1evj:C, 1evj:D, 1h6a:A, 1h6a:B, 1h6b:A, 1h6b:B, 1h6c:A, 1h6c:B, 1h6d:C, 1h6d:B, 1h6d:D, 1h6d:E, 1h6d:G, 1h6d:F, 1h6d:H, 1h6d:I, 1h6d:K, 1h6d:J, 1h6d:L, 1ofg:A, 1ofg:D, 1ofg:B, 1ofg:C, 1ofg:E, 1ofg:F, 1ryd:A, 1ryd:B, 1rye:A, 1rye:D, 1rye:B, 1rye:C
14 5mun:A 182 50 0.0292 0.0824 0.3000 6.3
15 2fty:A 532 104 0.0428 0.0414 0.2115 6.3 2fty:B, 2fty:C, 2fty:D, 2fvk:A, 2fvk:B, 2fvk:C, 2fvk:D, 2fvm:A, 2fvm:B, 2fvm:C, 2fvm:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218