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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KNNTHHFPKLLILVGAPGSGKSTFARYFIRTEDNWVRVNRDDFRLMQFGDSLMSPFYEERITKMVEASVIALLKNRTNVI
IDATNSSLRSLQDMVHTYTEYADISFKVFDLPVEELVKRQLQYTKEKFDFKPIPRALKETSLTYADQDTSLPKAVICDLD
GTLSLLNGRDPYNASTADQDLLNTPVAMVLKMAKQQGYKVILLSGRENAYREPTERFLAKYQIDYDLLLMRDTNDYRKDN
IIKKELFLEEIQGKYFVEFLLDDRNQVVDMWRRELALPCFQVNYGDF

The query sequence (length=287) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xru:D 287 287 1.0000 1.0000 1.0000 0.0
2 4xrp:A 311 309 1.0000 0.9228 0.9288 0.0 4xrp:D, 4xru:A
3 2ia5:H 301 312 0.3763 0.3588 0.3462 1.75e-44 2ia5:A, 2ia5:B, 2ia5:C, 2ia5:D, 2ia5:E, 2ia5:J, 1ltq:A, 1rc8:A, 1rpz:A, 1rrc:A, 5uj0:A, 5uj0:B
4 9d8a:A 172 35 0.0557 0.0930 0.4571 3.43e-06
5 3add:A 251 128 0.1185 0.1355 0.2656 0.001 3a4l:A, 3a4l:B, 3a4m:A, 3a4m:B, 3adb:A, 3adb:B, 3adc:A, 3adc:B, 3add:B, 3am1:A
6 3u7e:B 380 104 0.0941 0.0711 0.2596 0.018 3u7f:B, 3u7g:A, 3u7h:B, 3zvl:A, 3zvm:A, 3zvm:B, 3zvn:A
7 4iug:A 957 200 0.1847 0.0554 0.2650 0.033
8 3q8x:D 271 89 0.0801 0.0849 0.2584 0.045
9 6p6j:A 571 55 0.0767 0.0385 0.4000 0.068 8vsi:A
10 5htk:A 425 119 0.1045 0.0706 0.2521 0.14 5hr5:A, 5htk:B
11 3vx4:D 240 37 0.0523 0.0625 0.4054 0.34 3vx4:A
12 4ike:A 206 121 0.1115 0.1553 0.2645 0.40 4cf7:A, 4cf7:B, 4ike:B, 4jky:A, 4jky:B, 4jl5:A, 4jl5:B, 4jl6:A, 4jl6:B, 4jl8:A, 4jl8:B, 4jla:A, 4jla:B, 4jlb:A, 4jlb:B, 4jld:A, 4jld:B, 4jlo:A, 4jlo:B, 4jlp:A, 4jlp:B, 2rgx:A, 3sr0:A, 3sr0:B
13 4gp6:A 171 24 0.0488 0.0819 0.5833 0.41 4gp6:B, 4gp7:A, 4gp7:B, 4jst:A, 4jst:B, 4jsy:A, 4jsy:B, 4jt2:A, 4jt2:B, 4jt4:A, 4jt4:B, 4mde:A, 4mde:B, 4mdf:A, 4mdf:B, 4qm6:A, 4qm6:B, 4qm7:A, 4qm7:B
14 4v6w:AN 150 42 0.0488 0.0933 0.3333 0.78 6xu6:AN, 6xu7:AN, 6xu8:AN
15 7wge:A 698 65 0.0697 0.0287 0.3077 0.86
16 4wbd:A 540 100 0.1115 0.0593 0.3200 0.90
17 1lop:A 164 35 0.0523 0.0915 0.4286 1.0
18 1qzw:A 432 93 0.0941 0.0625 0.2903 1.1 3kl4:A, 5l3s:A, 5l3s:C, 5l3s:E, 5l3s:G, 5l3v:A, 5l3v:B, 1qzw:C, 1qzw:E, 1qzw:G, 3zn8:M
19 6rxt:CI 822 23 0.0348 0.0122 0.4348 1.2 6rxu:CI, 6rxv:CI, 6rxx:CI, 6rxy:CI, 6rxz:CI
20 1qf9:A 194 130 0.1115 0.1649 0.2462 1.2 1uke:A, 2ukd:A, 3ukd:A, 4ukd:A, 5ukd:A
21 5oql:Z 639 23 0.0348 0.0156 0.4348 1.2
22 3be4:A 215 120 0.0976 0.1302 0.2333 1.3
23 2gjs:A 150 41 0.0557 0.1067 0.3902 1.3 2dpx:A, 2dpx:B, 2gjs:B, 3q72:A, 3q72:B, 3q7p:A, 3q7p:B, 3q7q:A, 3q7q:B
24 3gkn:A 159 60 0.0627 0.1132 0.3000 1.3 3gkn:B, 5imd:A
25 5vc7:A 544 60 0.0662 0.0349 0.3167 1.4 5vc7:C, 5vc7:D, 5vc7:E, 5vc7:F, 5vc7:G
26 5ubv:A 244 25 0.0418 0.0492 0.4800 1.6 5ubv:B
27 6fvt:I 385 45 0.0523 0.0390 0.3333 1.8 6ef0:I, 6ef1:I, 6ef2:I, 6ef3:I, 6fvu:I, 6fvv:I, 6fvw:I, 6fvx:I, 6fvy:I, 5mp9:I, 5mpa:I, 5mpb:I, 5mpc:I, 7qo4:I, 7qo5:I, 7qo6:I
28 3h4m:A 261 98 0.0871 0.0958 0.2551 2.0 3h4m:B, 3h4m:C
29 6fvt:J 405 33 0.0488 0.0346 0.4242 2.1 6ef0:J, 6ef1:J, 6ef2:J, 6ef3:J, 6fvu:J, 6fvv:J, 6fvw:J, 6fvx:J, 6fvy:J, 5mp9:J, 5mpa:J, 5mpb:J, 5mpc:J, 7qo4:J, 7qo5:J, 7qo6:J
30 6fvt:H 426 32 0.0488 0.0329 0.4375 2.1 6ef0:H, 6ef1:H, 6ef2:H, 6fvu:H, 6fvv:H, 6fvw:H, 6fvx:H, 6fvy:H
31 7qo4:H 391 32 0.0488 0.0358 0.4375 2.1 6ef3:H, 5mp9:H, 5mpa:H, 5mpb:H, 5mpc:H, 7qo5:H, 7qo6:H
32 6msj:A 413 32 0.0488 0.0339 0.4375 2.2 8cvt:A, 5gjq:H, 5gjr:H, 5gjr:v, 5l4g:H, 5m32:c, 6msb:A, 6msd:A, 6mse:A, 6msg:A, 6msk:A, 7qxn:A, 7qxp:A, 7qxu:A, 7qxw:A, 7qxx:A, 7qy7:A, 7qya:A, 7qyb:A, 5t0c:AA, 5t0c:BA, 5t0g:A, 5t0h:A, 5t0i:A, 5t0j:A, 5vfp:A, 5vfq:A, 5vfr:A, 5vfs:A, 7w37:A, 7w38:A, 7w39:A, 7w3a:A, 7w3b:A, 7w3f:A, 7w3g:A, 7w3h:A, 7w3i:A, 7w3j:A, 7w3k:A, 6wjd:A, 6wjn:A
33 2ce7:D 413 20 0.0383 0.0266 0.5500 2.3 2ce7:A, 2ce7:B, 2ce7:E, 2ce7:F, 2cea:A, 2cea:B, 2cea:D, 2cea:E, 2cea:F
34 7p09:F 520 66 0.0697 0.0385 0.3030 2.3 7ksl:C, 7ksl:E, 7p0m:F
35 3lw7:B 170 18 0.0348 0.0588 0.5556 2.7
36 7zbh:B 374 20 0.0348 0.0267 0.5000 2.8 7zbh:A, 7zbh:D, 7zbh:F, 7zbh:I, 7zbh:K
37 4ux3:A 436 62 0.0732 0.0482 0.3387 2.8
38 4e4f:B 381 58 0.0523 0.0394 0.2586 2.9 4e4f:C, 4il2:A, 4il2:C, 4il2:D
39 5m32:h 332 37 0.0453 0.0392 0.3514 3.5
40 4u00:A 241 23 0.0418 0.0498 0.5217 3.7
41 8xqw:F 701 26 0.0418 0.0171 0.4615 3.8
42 4mrn:A 600 23 0.0418 0.0200 0.5217 3.9 4mrn:B, 4mrp:A, 4mrp:B, 4mrr:A, 4mrr:B, 4mrs:A, 4mrs:B, 4mrv:A, 4mrv:B, 6pam:A, 6pam:B, 6pam:C, 6pam:D, 6pam:E, 6pam:F, 6pam:G, 6pam:H, 6pan:A, 6pan:B, 6pao:A, 6pao:B, 6paq:A, 6paq:B, 6par:A, 6par:B, 6par:C, 6par:D, 6par:E, 6par:F, 6vqt:A, 6vqt:B
43 6uh4:B 326 76 0.0732 0.0644 0.2763 3.9
44 2www:D 314 16 0.0383 0.0350 0.6875 3.9 2www:A, 2www:B, 2www:C
45 8s91:D 621 17 0.0383 0.0177 0.6471 4.0 7dpd:A, 7dpd:B, 8s91:E, 8s91:F, 8s94:D, 8s94:F, 8s94:E
46 2dr3:D 242 80 0.0697 0.0826 0.2500 4.1 2dr3:A, 2dr3:B, 2dr3:C, 2dr3:E, 2dr3:F
47 3dm5:A 416 25 0.0453 0.0312 0.5200 4.4 3dm5:B
48 8bqf:D 215 19 0.0348 0.0465 0.5263 4.5 1ake:A, 1ake:B, 1ank:A, 1ank:B, 7apu:A, 7apu:B, 8bqf:A, 8bqf:B, 8bqf:C, 8bqf:E, 8bqf:F, 8crg:AA, 8crg:BA, 1e4v:A, 1e4v:B, 1e4y:A, 1e4y:B, 2eck:A, 2eck:B, 5eje:A, 5eje:B, 6ham:A, 6hap:A, 3hpq:A, 3hpq:B, 3hpr:A, 3hpr:B, 4jzk:A, 4jzk:B, 8q2b:A, 8q2b:B, 8rj4:A, 8rj4:B, 8rj4:C, 8rj4:D, 8rj6:A, 8rj6:B, 8rj9:A, 8rj9:B, 3x2s:A, 3x2s:B, 4x8l:A, 4x8l:B, 4x8o:A, 4x8o:B
49 6msg:C 396 37 0.0453 0.0328 0.3514 4.6 8cvt:C, 5gjq:J, 5gjr:J, 5gjr:x, 5l4g:J, 6msb:C, 6msd:C, 6msh:C, 6msj:C, 6msk:C, 7qxn:C, 7qxp:C, 7qxu:C, 7qxx:C, 7qy7:C, 7qyb:C, 5t0c:AC, 5t0c:BC, 5t0g:C, 5t0h:C, 5vfq:C, 5vfs:C, 7w37:C, 7w38:C, 7w39:C, 7w3a:C, 7w3b:C, 7w3c:C, 7w3f:C, 7w3g:C, 7w3h:C, 7w3i:C, 7w3j:C, 7w3m:C, 6wjd:C
50 7wi7:B 566 17 0.0383 0.0194 0.6471 4.6
51 3w3w:A 1028 49 0.0662 0.0185 0.3878 4.9 5h2v:A, 3w3x:A, 3w3y:A, 4zj7:A
52 2iyv:A 179 20 0.0383 0.0615 0.5500 5.1 3baf:A, 4bqs:A, 4bqs:B, 4bqs:C, 2dfn:A, 2dft:A, 2dft:B, 2dft:C, 2dft:D, 2g1k:A, 2iyq:A, 2iyr:A, 2iyr:B, 2iys:A, 2iyu:A, 2iyw:A, 2iyx:A, 2iyy:A, 2iyz:A, 1l4u:A, 1l4y:A, 1u8a:A, 1we2:A, 1zyu:A
53 7aju:CL 808 23 0.0348 0.0124 0.4348 5.2 6zqd:CL, 6zqe:CL, 6zqf:CL, 6zqg:CL
54 7wiv:A 571 35 0.0557 0.0280 0.4571 5.3 7wiw:A, 7wix:A
55 8gju:F 332 16 0.0383 0.0331 0.6875 5.3 8gju:D, 8gju:A, 8gju:B
56 7suk:SI 802 23 0.0348 0.0125 0.4348 5.6 7d63:RJ, 6ke6:RJ, 6lqp:RJ, 6lqq:RJ, 6lqr:RJ, 6lqu:RJ, 6lqv:RJ, 5wlc:SI
57 7d4i:RJ 738 23 0.0348 0.0136 0.4348 5.7 7d5t:RJ, 6lqs:RJ, 6lqt:RJ
58 4k46:A 214 19 0.0348 0.0467 0.5263 5.8
59 7ajt:CL 781 23 0.0348 0.0128 0.4348 5.9 7d5s:RJ, 6zqa:CL, 6zqb:CL, 6zqc:CL
60 7n59:A 590 49 0.0627 0.0305 0.3673 6.0 7n59:B, 7n5a:A, 7n5a:B, 7n5b:A, 7n5b:B
61 7wtl:CL 610 23 0.0348 0.0164 0.4348 6.5 5wyj:B1, 5wyk:B1
62 6hd3:A 450 19 0.0383 0.0244 0.5789 6.6 6hd3:C
63 6ut3:B 365 24 0.0383 0.0301 0.4583 6.7
64 6ut5:A 395 24 0.0383 0.0278 0.4583 6.7 6ut3:C, 6ut3:D, 6ut3:E, 6ut3:F, 6ut4:A, 6ut4:B, 6ut4:C, 6ut4:D, 6ut4:E, 6ut4:F, 6ut5:B, 6ut5:C, 6ut5:D, 6ut5:E, 6ut5:F, 6ut7:A, 6ut7:B, 6ut7:C, 6ut7:D, 6ut7:E, 6ut7:F, 6ut7:H, 6ut7:I, 6ut7:J, 6ut7:K, 6ut7:L, 6ut7:M, 6ut8:A, 6ut8:B, 6ut8:C, 6ut8:D, 6ut8:E, 6ut8:F
65 7dtv:A 779 22 0.0383 0.0141 0.5000 6.9 7dtu:A, 7dtu:B, 7dtv:B
66 6he8:I 390 45 0.0488 0.0359 0.3111 7.2 6he4:H, 6he4:I, 6he4:J, 6he4:K, 6he4:L, 6he8:J, 6he8:K, 6he8:L, 6he8:M, 6he9:H, 6he9:I, 6he9:J, 6he9:K, 6he9:L, 6hea:H, 6hea:I, 6hea:J, 6hea:K, 6hea:L, 6hea:M, 6hec:H, 6hec:I, 6hec:J, 6hec:L, 6hec:M, 6hed:H, 6hed:I, 6hed:K, 6hed:L, 6hed:M
67 6jdv:A 1036 55 0.0662 0.0183 0.3455 7.5 6kc8:A
68 3rph:A 277 100 0.0836 0.0866 0.2400 7.6 3rpz:A, 3rq2:A, 3rq5:A, 3rq6:A, 3rq8:A, 3rqh:A, 3rqq:A, 3rqx:A
69 2r65:A 249 20 0.0348 0.0402 0.5000 8.1 2r65:B, 2r65:C, 2r65:D, 2r65:E
70 8igq:A 227 24 0.0383 0.0485 0.4583 8.5 8idd:B, 8idd:A, 8igq:B, 8jia:A, 8jia:B
71 7cq2:A 274 111 0.0697 0.0730 0.1802 8.8
72 3nzt:A 498 24 0.0348 0.0201 0.4167 8.9
73 7epk:A 426 63 0.0697 0.0469 0.3175 9.6
74 5mtv:A 379 46 0.0453 0.0343 0.2826 9.9 5mvf:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218