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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIF
AYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNSERLQMFDD
PRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKVKIGKLNLVDLAGSENINQSL
LTLGRVITALVEHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE

The query sequence (length=309) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5zo8:A 331 327 0.9968 0.9305 0.9419 0.0 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
2 4ap0:C 311 312 0.9741 0.9678 0.9647 0.0
3 4aqv:C 361 348 0.9838 0.8421 0.8736 0.0 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
4 6ta3:K 334 343 0.9482 0.8772 0.8542 0.0 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
5 3wpn:A 309 330 0.9094 0.9094 0.8515 0.0
6 7lxr:B 344 338 0.6181 0.5552 0.5651 9.14e-125 7lxr:A, 6vpo:C, 2wbe:C
7 6s8m:K 344 337 0.5243 0.4709 0.4807 2.56e-99
8 5mm7:K 397 380 0.5793 0.4509 0.4711 1.02e-95 5mm4:K
9 5m5i:C 369 358 0.5307 0.4444 0.4581 3.85e-95 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
10 7nba:K 331 343 0.4951 0.4622 0.4461 1.32e-86
11 3b6u:B 343 335 0.4790 0.4315 0.4418 3.06e-86 3b6u:A
12 3zfd:A 340 335 0.4757 0.4324 0.4388 2.21e-83 3zfc:A
13 3b6v:A 306 315 0.4595 0.4641 0.4508 9.64e-83 3b6v:B
14 7a5e:A 338 340 0.4790 0.4379 0.4353 5.52e-81 7a5e:B
15 1goj:A 354 341 0.4757 0.4153 0.4311 1.04e-76
16 7a3z:A 307 319 0.4531 0.4560 0.4389 1.94e-76
17 2vvg:B 309 321 0.4563 0.4563 0.4393 4.45e-76 2vvg:A
18 2y65:C 343 318 0.4434 0.3994 0.4308 4.05e-71 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
19 6zpi:C 332 296 0.4369 0.4066 0.4561 4.48e-71 4bn2:A, 4bn2:B, 6zph:B
20 4bn2:C 311 321 0.4725 0.4695 0.4548 1.37e-69
21 1mkj:A 336 321 0.4595 0.4226 0.4424 1.04e-68 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
22 3x2t:A 311 318 0.4531 0.4502 0.4403 5.47e-68 2kin:A, 3kin:A, 3kin:C
23 7rx0:C 328 333 0.4304 0.4055 0.3994 7.05e-67 6mlq:C, 6mlr:C
24 3lre:B 300 318 0.4110 0.4233 0.3994 1.40e-65 3lre:A, 7rsi:C
25 4uy0:C 333 336 0.4595 0.4264 0.4226 1.42e-65
26 5hnw:K 329 328 0.4498 0.4225 0.4238 2.55e-65 5hle:A, 5hny:K, 3x2t:B
27 5ocu:K 333 337 0.4239 0.3934 0.3887 5.62e-65 5ogc:K
28 7z2b:K 308 331 0.4142 0.4156 0.3867 1.12e-64
29 7eo9:A 351 338 0.4078 0.3590 0.3728 2.87e-63 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
30 7x4n:E 332 336 0.4304 0.4006 0.3958 3.34e-62
31 6wwk:K 368 360 0.4337 0.3641 0.3722 1.41e-61 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
32 1t5c:A 322 327 0.4207 0.4037 0.3976 3.93e-61 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
33 2xt3:A 300 318 0.4045 0.4167 0.3931 6.06e-61 4a14:A
34 6a20:A 395 342 0.4239 0.3316 0.3830 7.82e-61 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
35 2owm:A 328 315 0.4175 0.3933 0.4095 3.99e-60 2owm:B, 2owm:C, 2owm:D
36 8uto:N 389 367 0.4078 0.3239 0.3433 1.49e-58 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
37 7tr1:K 346 352 0.4337 0.3873 0.3807 4.36e-57 7lff:A, 7lff:B
38 7wrg:B 783 342 0.4207 0.1660 0.3801 1.00e-56
39 5zbs:C 323 333 0.4142 0.3963 0.3844 2.17e-56 3gbj:A, 3gbj:C
40 7rs5:K 346 357 0.4078 0.3642 0.3529 1.99e-55 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
41 5gsz:A 306 326 0.3981 0.4020 0.3773 4.82e-55
42 7wrg:A 812 356 0.4207 0.1601 0.3652 6.37e-55
43 4ozq:B 687 333 0.4110 0.1849 0.3814 1.23e-54 4ozq:A
44 3cob:A 355 340 0.3883 0.3380 0.3529 3.66e-54 3cob:C, 1sdm:A
45 7tr3:K 418 301 0.3851 0.2847 0.3953 2.06e-53 7tqx:K, 7tqy:K, 7tr0:K
46 5wde:A 320 333 0.3948 0.3812 0.3664 5.43e-52
47 1cz7:D 365 319 0.3592 0.3041 0.3480 7.83e-52 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
48 3nwn:A 308 280 0.3463 0.3474 0.3821 6.35e-50
49 7n61:0X 420 347 0.3851 0.2833 0.3429 2.57e-49 7n61:0Y, 7n61:0Z, 7n61:1A
50 3cnz:A 333 282 0.3366 0.3123 0.3688 3.53e-49 3cnz:B
51 3h4s:A 359 334 0.3689 0.3175 0.3413 2.00e-48 4frz:A, 4frz:B
52 3dcb:A 299 317 0.3592 0.3712 0.3502 4.60e-48 3dc4:A, 3dco:N, 3pxn:A
53 5mio:C 477 339 0.3981 0.2579 0.3628 5.61e-48 1v8j:A, 5xjb:A
54 5nd4:C 337 295 0.3236 0.2967 0.3390 3.33e-46
55 4gkr:B 307 324 0.3689 0.3713 0.3519 1.25e-45 4gkr:A
56 6nje:A 297 327 0.3786 0.3939 0.3578 3.36e-44
57 5wdh:A 296 311 0.3592 0.3750 0.3569 6.83e-44
58 6bbn:E 378 332 0.3689 0.3016 0.3434 1.62e-43 2gry:A
59 3u06:B 344 314 0.3366 0.3023 0.3312 2.83e-42 3l1c:B, 1n6m:B
60 6b0l:K 368 292 0.3366 0.2826 0.3562 3.20e-42 6b0c:K
61 5xja:A 337 330 0.3754 0.3442 0.3515 4.95e-42 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
62 4etp:A 379 343 0.3883 0.3166 0.3499 5.62e-42 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
63 5nd2:C 280 308 0.3301 0.3643 0.3312 9.97e-42
64 4ubf:A 309 317 0.3722 0.3722 0.3628 3.67e-41
65 5nd7:C 300 322 0.3366 0.3467 0.3230 9.89e-41
66 5w3d:B 313 300 0.3301 0.3259 0.3400 6.28e-40
67 3t0q:A 304 333 0.3689 0.3750 0.3423 4.93e-39
68 4h1g:A 670 331 0.3366 0.1552 0.3142 3.29e-36
69 1f9w:A 300 317 0.3366 0.3467 0.3281 1.28e-35 1f9w:B
70 8bjs:A 343 371 0.3172 0.2857 0.2642 2.39e-31
71 8dmf:A 718 72 0.0680 0.0292 0.2917 0.27 7uvp:A
72 6qw6:5J 803 65 0.0680 0.0262 0.3231 7.7 8h6e:4G, 8h6j:4G, 8h6k:4G, 8h6l:4G, 8qp8:N, 6qx9:5J, 8y6o:G
73 8r09:N 834 65 0.0680 0.0252 0.3231 8.9 6ahd:N, 5o9z:G, 8q7n:N, 8qo9:N, 8qpe:N, 8qzs:N, 8r0b:N, 8rc0:E, 8rm5:N
74 6fkk:A 513 69 0.0615 0.0370 0.2754 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218