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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KNHNTFDLWHTIREETAAAAAAEPMLASFLHQTVLRHESLGSVLAYHLSSKLGSPIMDVRALFEIYQQALSDTQISKCVE
ADLKAIYERDPACDEYSLPLLYFKGFHAIQAHRINHRLYLDGRKTLAYFLQNRMSEVFGVDIHPAARLGYGLMLDHATGF
VAGETAVLGNNISILHGVTLGGSGKEGGDRHPKIGDGVMIGANASILGNIRIGSNAKIGAGSVVVSDVPPSITVVGVPAK
PVARSLKTPSADMDQNIQ

The query sequence (length=258) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6wye:A 261 261 0.9961 0.9847 0.9847 0.0 7ra4:A, 7ra4:C, 7ra4:B, 6wye:C, 6wye:B, 6wye:D, 6wye:F, 6wye:E
2 1t3d:A 262 251 0.5581 0.5496 0.5737 1.06e-99 7e3y:A, 7e3y:C, 7e3y:B, 8i04:A, 8i04:C, 8i04:B, 8i06:A, 8i06:B, 8i09:A, 8i09:B, 8i09:C, 8i09:D, 8i09:E, 8i09:F, 8i09:G, 8i09:H, 8i09:I, 8i09:J, 8i09:K, 8i09:L, 6jvu:A, 6jvu:C, 6jvu:B, 6jvu:D, 6jvu:F, 6jvu:E, 1t3d:B, 1t3d:C
3 1ssq:D 257 253 0.5310 0.5331 0.5415 2.80e-96 1ssq:A, 1sst:A, 1sst:B, 1sst:C
4 3gvd:I 272 251 0.5543 0.5257 0.5697 7.30e-96 3gvd:A, 3gvd:C, 3gvd:B, 3gvd:D, 3gvd:F, 3gvd:E, 3gvd:G, 3gvd:H, 3gvd:J, 3gvd:K, 3gvd:L
5 4h7o:A 258 251 0.5194 0.5194 0.5339 1.19e-90 4h7o:C, 4h7o:B
6 4n69:A 243 236 0.5116 0.5432 0.5593 4.48e-88 4n69:B, 4n6b:A, 4n6b:E, 4n6b:B, 4n6b:C, 4n6b:D, 4n6b:F
7 4hzd:A 250 239 0.4729 0.4880 0.5105 2.00e-85 4hzc:F, 4hzc:J
8 7bw9:A 280 197 0.2674 0.2464 0.3503 1.90e-34 7bw9:B, 7bw9:C
9 3p47:A 270 168 0.2442 0.2333 0.3750 5.95e-28 3q1x:A
10 1kru:A 201 113 0.1357 0.1741 0.3097 4.91e-09 1kqa:A, 1kqa:B, 1kqa:C, 1krr:A, 1krr:B, 1krr:C, 1kru:B, 1kru:C, 1krv:A, 1krv:C, 1krv:B
11 4isx:A 186 114 0.1473 0.2043 0.3333 2.28e-08 4isx:B
12 4eaa:A 210 186 0.2054 0.2524 0.2849 1.30e-07 4ea7:A, 4ea8:A, 4ea9:A, 4eab:A
13 4mzu:F 294 93 0.1163 0.1020 0.3226 1.63e-06 4mzu:A, 4mzu:C, 4mzu:E, 4mzu:B, 4mzu:D, 4mzu:G, 4mzu:I, 4mzu:K, 4mzu:H, 4mzu:J, 4mzu:L, 4zu4:A, 4zu4:B, 4zu4:C
14 3igj:C 188 58 0.1085 0.1489 0.4828 3.41e-06 3igj:A, 3igj:B
15 7s3u:A 145 90 0.1240 0.2207 0.3556 5.93e-06 7s3w:A, 7s41:A, 7s42:A, 7s43:A, 7s44:A, 7s45:A
16 8j40:A 209 53 0.0853 0.1053 0.4151 3.46e-05
17 3nz2:J 185 54 0.0969 0.1351 0.4630 3.60e-05 3ect:A, 3nz2:A, 3nz2:C, 3nz2:B, 3nz2:D, 3nz2:E, 3nz2:F, 3nz2:G, 3nz2:H, 3nz2:I, 3nz2:K, 3nz2:L
18 5u2k:A 190 51 0.0814 0.1105 0.4118 4.31e-05 5v0z:A, 5v0z:C, 5v0z:B, 3v4e:A, 3v4e:C, 3v4e:B
19 7uuk:C 276 49 0.0969 0.0906 0.5102 6.77e-05 7jm1:A, 7jm1:C, 7jm1:B, 7jm2:A, 7jm2:C, 7jm2:B, 7uuj:A, 7uuj:C, 7uuj:B, 7uuk:A, 7uuk:B, 7uul:A, 7uul:B, 7uul:D, 7uul:C, 7uul:F, 7uul:E, 7uum:A, 7uun:A, 7uuo:B
20 7txp:A 209 119 0.1395 0.1722 0.3025 1.28e-04 7txq:A, 7txs:A
21 1hm8:A 458 43 0.0659 0.0371 0.3953 1.36e-04 4aaw:A, 4ac3:A, 1g97:A, 1hm8:B, 1hm9:A, 1hm9:B, 7kr9:A
22 3mqg:C 192 53 0.0853 0.1146 0.4151 1.42e-04 3mqg:A, 3mqg:B, 3mqg:D, 3mqg:E, 3mqg:F, 3mqh:A, 3mqh:C, 3mqh:B, 3mqh:D, 3mqh:F, 3mqh:E
23 4m99:A 206 50 0.0814 0.1019 0.4200 3.55e-04 4m99:B, 4m99:C
24 4ihh:E 340 111 0.1357 0.1029 0.3153 5.10e-04 4ihf:D, 4ihf:E, 4ihf:F, 4ihf:A, 4ihf:B, 4ihf:C, 4ihg:E, 4ihg:C, 4ihg:B, 4ihg:D, 4ihh:A, 4ihh:C, 4ihh:B, 4ihh:D, 4ihh:F, 6p83:A, 6p83:C, 6p83:B, 6p84:A, 6p84:C, 6p84:B, 6p85:A, 6p85:C, 6p85:B, 6p86:A, 6p86:C, 6p86:B, 6p87:A, 6p87:C, 6p87:B, 6p88:A, 6p88:C, 6p88:B, 6p89:A, 6p89:C, 6p89:B, 6p8a:A, 6p8a:C, 6p8a:B, 6p8b:A, 6p8b:C, 6p8b:B
25 8vr7:E 180 54 0.0736 0.1056 0.3519 6.68e-04 8vr6:A, 8vr7:A, 8vr7:B, 8vr7:C, 8vr7:D, 8vr7:F
26 8gpm:A 193 56 0.0930 0.1244 0.4286 8.61e-04 8gpp:A, 8gpp:B, 8gpp:C
27 4eqy:G 260 51 0.0659 0.0654 0.3333 8.90e-04
28 6ive:A 168 113 0.1318 0.2024 0.3009 0.002 6ive:B, 6ive:C, 6ive:D, 6ive:E, 6ive:F
29 3fsb:A 260 51 0.0814 0.0808 0.4118 0.002 3fs8:A, 3fs8:B, 3fsb:B, 3fsc:A, 3fsc:B
30 1khr:A 206 53 0.0736 0.0922 0.3585 0.003 3dho:A, 3dho:C, 3dho:B, 3dho:D, 3dho:F, 3dho:E, 1khr:B, 1khr:C, 1khr:D, 1khr:E, 1khr:F, 1kk4:A, 1kk4:B, 1kk4:C, 1kk4:D, 1kk4:E, 1kk4:F, 1mr9:A, 1mr9:C, 1mr9:B, 1mr9:X, 1mr9:Z, 1mr9:Y, 1mrl:A, 1mrl:B, 1mrl:C
31 4n27:A 175 76 0.1047 0.1543 0.3553 0.005 4n27:B, 4n27:C, 4n27:D, 4n27:E, 4n27:F
32 2xat:A 208 53 0.0736 0.0913 0.3585 0.006
33 7zw9:A 173 55 0.0891 0.1329 0.4182 0.009
34 2fko:A 173 86 0.1163 0.1734 0.3488 0.011 1v3w:A, 1v67:A
35 3r8y:A 203 99 0.1357 0.1724 0.3535 0.011 3r8y:C, 3r8y:D, 3r8y:F
36 6pub:A 210 47 0.0814 0.1000 0.4468 0.016 6u9c:A, 6u9c:B, 6u9c:C
37 4hus:A 212 54 0.0736 0.0896 0.3519 0.020 4hur:A, 4hur:B, 4hur:C, 4hus:C, 6x3c:A, 6x3c:F, 6x3c:B, 6x3c:C, 6x3c:D, 6x3c:E, 6x3j:A, 6x3j:B, 6x3j:D, 6x3j:C, 6x3j:E, 6x3j:F
38 7ojp:Z 261 85 0.0969 0.0958 0.2941 0.021 5dep:A, 5dep:B, 5dep:D, 5dep:E, 5dep:F, 5dg3:A, 5dg3:B, 5dg3:C, 5dg3:D, 5dg3:E, 7oj6:A, 7oj6:B, 7oj6:C, 7ojp:A, 7ojp:B, 7ojp:C, 7ojp:D, 7ojp:E, 7ojp:F, 7ojp:G, 7ojp:H, 7ojp:I, 7ojp:J, 7ojp:K, 7ojp:L, 7ojp:M, 7ojp:N, 7ojp:O, 7ojp:P, 7ojp:Q, 7ojp:R, 7ojp:S, 7ojp:T, 7ojp:U, 7ojp:V, 7ojp:W, 7ojp:X, 7ojp:Y, 7ojp:a, 7ojp:b, 7ojp:c, 7ojp:d, 7ojq:A, 7ojq:B, 7ojq:C, 7ojw:A, 7ojw:B, 7ojw:C, 7ojy:A, 7ojy:B, 7ojy:C, 7ok1:A, 7ok1:B, 7ok1:C, 7ok2:1, 7ok2:Y, 7ok2:Z, 7ok2:2, 7ok2:4, 7ok2:3, 7ok2:A, 7ok2:B, 7ok2:C, 7ok2:D, 7ok2:E, 7ok2:F, 7ok2:G, 7ok2:I, 7ok2:H, 7ok2:J, 7ok2:L, 7ok2:K, 7ok2:M, 7ok2:N, 7ok2:O, 7ok2:P, 7ok2:Q, 7ok2:R, 7ok2:S, 7ok2:T, 7ok2:U, 7ok2:V, 7ok2:X, 7ok2:W, 7oka:A, 7oka:C, 7oka:B, 7oka:D, 7oka:E, 7oka:F, 7oka:G, 7oka:H, 7oka:I, 7oka:M, 7oka:N, 7oka:O, 7oka:J, 7oka:K, 7oka:L, 7oka:P, 7oka:Q, 7oka:R, 7oka:S, 7oka:T, 7oka:U, 7oka:V, 7oka:W, 7oka:X, 7oka:Y, 7oka:Z, 7oka:a, 7oka:b, 7oka:d, 7oka:c, 7okb:A, 7okb:B, 7okb:C, 7okb:D, 7okb:E, 7okb:F, 7okb:G, 7okb:H, 7okb:I, 7okb:M, 7okb:N, 7okb:O, 7okb:J, 7okb:K, 7okb:L, 7okb:P, 7okb:Q, 7okb:R, 7okb:S, 7okb:T, 7okb:U, 7okb:V, 7okb:W, 7okb:X, 7okb:Y, 7okb:Z, 7okb:a, 7okb:b, 7okb:c, 7okb:d, 7t5r:A, 7t5r:B, 7t5r:C, 7t5r:D, 7t5r:F, 7t5r:E, 7t5s:A, 7t5s:B, 7t5s:C, 7t5s:D, 7t5s:F, 7t5s:E, 7t5x:A, 7t5x:B, 7t5x:C, 7t5x:D, 7t5x:F, 7t5x:E, 7t5z:A, 7t5z:B, 7t5z:C, 7t5z:D, 7t5z:E, 7t5z:F, 7t60:A, 7t60:B, 7t60:C, 7t60:D, 7t60:F, 7t60:E, 7t61:A, 7t61:B, 7t61:C, 7t61:D, 7t61:E, 7t61:F, 6uee:A, 6uee:C, 6uee:B, 6uee:D, 6uee:E, 6uee:F, 6ueg:A, 6ueg:C, 6ueg:B, 6ueg:D, 6ueg:E, 6ueg:F
39 6sc4:B 178 57 0.0775 0.1124 0.3509 0.025 6sc4:A, 6sc4:C, 6sc4:D, 6sc4:E
40 6sc4:B 178 39 0.0388 0.0562 0.2564 7.4 6sc4:A, 6sc4:C, 6sc4:D, 6sc4:E
41 3bss:A 194 101 0.1047 0.1392 0.2673 0.064 3bsy:A, 3bsy:C, 3bsy:B, 5t2y:A, 5t2y:B, 5tyh:A, 2vhe:A, 2vhe:B
42 2wle:C 211 45 0.0581 0.0711 0.3333 0.086 2wle:A, 2wle:B, 2wlf:A, 2wlf:C, 2wlf:B, 2wlg:A, 2wlg:C, 2wlg:B
43 2wle:C 211 67 0.0853 0.1043 0.3284 0.31 2wle:A, 2wle:B, 2wlf:A, 2wlf:C, 2wlf:B, 2wlg:A, 2wlg:C, 2wlg:B
44 3i3a:A 259 81 0.0930 0.0927 0.2963 0.14 3i3a:B, 3i3a:C, 3i3x:A, 3i3x:B, 3i3x:C
45 8ok6:A 368 229 0.2054 0.1440 0.2314 0.16 8ok4:A, 8ok5:A, 8ok6:C, 8onh:A, 8onh:B, 8onh:C, 8onh:G, 8onh:J, 8onh:K, 8onh:L, 8onh:N
46 3d8v:A 478 41 0.0620 0.0335 0.3902 0.18 3dj4:A, 4g3p:A, 4g3q:A, 4g3s:A, 4g87:A, 6ge9:A, 4hcq:A, 4k6r:A, 2qkx:A, 3spt:A, 3st8:A
47 6pxa:E 221 37 0.0581 0.0679 0.4054 0.21 6pxa:A, 6pxa:B, 6pxa:C, 6pxa:D, 6pxa:F, 6pxa:G, 6pxa:H, 6pxa:I, 6pxa:J, 6pxa:K, 6pxa:L, 5ux9:A, 5ux9:B, 5ux9:C, 5ux9:D
48 3vnp:A 171 50 0.0853 0.1287 0.4400 0.22 3vnp:B, 3vnp:C
49 2oi6:B 452 84 0.0969 0.0553 0.2976 0.22 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
50 4e1k:A 450 89 0.0930 0.0533 0.2697 0.29 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
51 4fce:A 441 42 0.0543 0.0317 0.3333 0.52
52 3ixc:A 166 37 0.0581 0.0904 0.4054 0.52
53 3kwc:A 205 61 0.0775 0.0976 0.3279 0.82 3kwc:B, 3kwc:C, 3kwc:D, 3kwc:E, 3kwc:F, 3kwd:A, 3kwe:A
54 3foq:A 439 37 0.0581 0.0342 0.4054 0.85
55 3vbm:E 193 51 0.0736 0.0984 0.3725 1.0 3vbi:A, 3vbi:E, 3vbi:C, 3vbj:A, 3vbj:C, 3vbj:E, 3vbk:A, 3vbk:E, 3vbk:C, 3vbl:A, 3vbl:C, 3vbl:E, 3vbm:A, 3vbm:C, 3vbn:A, 3vbn:E, 3vbn:C, 3vbp:A, 3vbp:E, 3vbp:C
56 7aqq:y 268 40 0.0504 0.0485 0.3250 1.2 7ar7:y, 7ar8:y, 7arb:y, 8bef:y, 8bpx:y, 8bq5:y, 8bq6:y
57 7whs:A 366 47 0.0736 0.0519 0.4043 1.7 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
58 8e62:C 183 84 0.0930 0.1311 0.2857 2.2 8e62:A, 8e62:B, 8e62:D, 8e62:E, 8e62:F
59 7okc:A 264 82 0.0814 0.0795 0.2561 2.9 2aq9:A, 6hy2:X, 4j09:A, 2jf3:A, 6p9p:A, 6p9q:A, 6p9r:A, 6p9s:A, 6p9t:A, 2qia:A, 2qiv:X
60 7l7y:AAA 217 29 0.0504 0.0599 0.4483 3.6 7l7z:AAA, 7l81:AAA, 7l82:AAA
61 2iu8:A 346 85 0.0969 0.0723 0.2941 4.0 2iu8:B, 2iu8:C, 2iu9:A, 2iu9:B, 2iu9:C, 2iua:A, 2iua:C
62 2ggq:A 401 35 0.0620 0.0399 0.4571 4.9 5z09:A, 5z09:B, 5z09:C, 5z09:D
63 8hub:C 572 157 0.1550 0.0699 0.2548 7.5 8hub:D
64 3r3r:A 184 69 0.0775 0.1087 0.2899 7.9
65 4r37:A 255 36 0.0659 0.0667 0.4722 8.7
66 3tio:F 177 40 0.0504 0.0734 0.3250 9.5 3tio:A, 3tio:B, 3tio:C, 3tio:D, 3tio:E, 3tis:A, 3tis:B, 3tis:C
67 7o54:A 165 89 0.0969 0.1515 0.2809 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218