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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KMEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTV
QFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIF
IGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIK
ASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEA
PVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPM
HRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDS
QFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

The query sequence (length=542) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5csl:B 2072 538 0.9668 0.2529 0.9740 0.0 5ctb:A, 5ctb:C, 5ctc:A, 5ctc:B, 5ctc:C, 5cte:B, 5cte:C, 3h0s:A, 3k8x:A, 3k8x:B, 3k8x:C, 1od2:A, 1od2:B, 3pgq:A, 3pgq:C, 3tv5:A, 3tv5:B, 3tv5:C, 3tvu:A, 3tvu:B, 3tvu:C, 3tvw:A, 3tvw:B, 3tvw:C, 3tz3:A, 3tz3:B, 3tz3:C, 1w96:A, 1w96:B, 1w96:C, 4wyo:B, 4wyo:C, 4wz8:B, 4wz8:C
2 5csl:A 2050 541 0.9649 0.2551 0.9667 0.0
3 3jrx:A 496 506 0.5996 0.6552 0.6423 0.0 5kkn:B, 5kkn:C
4 3gid:A 460 497 0.5627 0.6630 0.6137 0.0 3gid:B
5 7ybu:A 670 506 0.2878 0.2328 0.3083 2.69e-60 7ybu:B, 7ybu:D, 7ybu:F, 7ybu:H, 7ybu:J
6 6ojh:A 445 515 0.2915 0.3551 0.3068 1.11e-58 4mv1:A, 4mv3:A, 4mv4:A, 4mv8:A, 6oi8:A
7 3tw6:B 1129 522 0.2934 0.1408 0.3046 1.30e-58 4jx4:A, 4jx4:B, 4jx4:C, 4jx4:D, 4jx5:A, 4jx5:B, 4jx5:C, 4jx5:D, 4jx6:A, 4jx6:B, 4jx6:C, 4jx6:D, 4loc:A, 4loc:B, 4loc:C, 4loc:D, 4m6v:A, 4m6v:B, 4m6v:C, 4m6v:D, 4mfd:A, 4mfd:B, 4mfd:C, 4mfd:D, 4mfe:A, 4mfe:B, 4mfe:C, 4mfe:D, 4mim:A, 4mim:B, 4mim:C, 4mim:D, 3tw6:C, 3tw6:D
8 8hz4:A 456 505 0.2878 0.3421 0.3089 1.29e-57 8hz4:B, 8hz4:C, 8hz4:D
9 2vpq:B 448 496 0.2897 0.3504 0.3165 1.60e-57 2vpq:A
10 4rzq:A 422 511 0.2694 0.3460 0.2857 1.64e-57 4mv6:A, 4mv7:A, 4mv9:A
11 1dv1:B 428 505 0.2675 0.3388 0.2871 1.93e-57
12 1dv2:A 450 512 0.2786 0.3356 0.2949 2.44e-57 1dv1:A, 1dv2:B, 3g8c:A, 3g8c:B, 3g8d:B, 2j9g:A, 2j9g:B, 3jzf:B, 3jzi:A, 3jzi:B, 6oi9:A, 6oi9:B, 3rup:A, 3rup:B, 3rv3:A, 3rv3:B, 3rv4:A, 2v58:A, 2v58:B, 2v59:A, 2v59:B, 2v5a:A, 2vr1:A, 2w6m:A, 2w6m:B, 2w6n:A, 2w6n:B, 2w6o:A, 2w6o:C, 2w6p:A, 2w6q:A, 2w6q:B, 2w6z:A, 2w70:A, 2w70:B, 2w71:A, 2w71:C
13 8rth:A 666 509 0.2768 0.2252 0.2947 8.50e-57 8rth:C, 8rth:E, 8rth:G, 8rth:I, 8rth:K
14 5vyz:A 1144 506 0.3007 0.1425 0.3221 2.12e-55 5vyw:D, 5vyz:B, 5vyz:D, 5vz0:A, 5vz0:B, 5vz0:D, 7zyy:A, 7zyy:C, 7zyy:B, 7zyy:D, 7zyz:A, 7zz0:A, 7zz1:A, 7zz2:A, 7zz3:A, 7zz3:C, 7zz3:B, 7zz3:D, 7zz4:A, 7zz5:A, 7zz6:D, 7zz6:A, 7zz8:A, 7zz8:C, 7zz8:D, 7zz8:B
15 3ouu:A 446 496 0.2878 0.3498 0.3145 1.41e-54 3ouu:B, 3ouz:A, 3ouz:B
16 7kct:A 453 513 0.2768 0.3311 0.2924 8.32e-54 7kbl:A, 7kbl:B, 7kc7:A, 7kct:B
17 3n6r:G 646 493 0.2712 0.2276 0.2982 9.10e-54 3n6r:I, 3n6r:K
18 2vqd:A 447 513 0.2786 0.3378 0.2943 7.11e-53
19 8sgx:X 657 507 0.2768 0.2283 0.2959 7.51e-53 8sgx:S, 8sgx:Z, 8sgx:V, 8sgy:V, 8sgy:B, 8sgy:S, 8sgy:Z, 8sgy:Y, 8sgz:V, 8sgz:Z, 8sgz:X, 8sgz:S, 8sgz:B, 8sgz:Y
20 8j78:I 651 507 0.2786 0.2320 0.2978 2.08e-52 8j78:C, 8j7d:D, 8j7d:F, 8j7d:I, 8j7d:L, 8jaw:A, 8jaw:C, 8jaw:E, 8jaw:F, 8jaw:H, 8jaw:K, 8k2v:A, 8k2v:B, 8k2v:C, 8k2v:D, 8k2v:E, 8k2v:F
21 3bg5:A 1137 513 0.2731 0.1302 0.2885 1.15e-51 3bg5:C, 8gk8:A, 8gk8:B, 3hb9:A, 3hb9:C, 3hbl:A, 3hbl:C, 4hnt:A, 4hnt:C, 4hnu:A, 4hnu:C, 4hnv:A, 4hnv:C
22 7wtb:B 1147 512 0.2694 0.1273 0.2852 9.21e-48 3bg3:A, 3bg3:B, 3bg3:C, 3bg3:D, 3bg9:A, 3bg9:B, 3bg9:C, 3bg9:D, 8j7o:A, 8j7o:B, 8j7o:C, 8j7o:E, 7wta:C, 7wta:B, 7wta:D, 7wta:A, 7wtb:C, 7wtb:A, 7wtb:D, 7wtc:C, 7wtc:A, 7wtc:B, 7wtc:D, 7wtd:C, 7wtd:D, 7wte:C, 7wte:D
23 2qf7:B 1017 516 0.2694 0.1436 0.2829 1.97e-46 3tw7:A, 3tw7:B
24 8hwl:A 941 244 0.1661 0.0956 0.3689 2.12e-37 8hwl:B, 8hwl:C, 8hwl:E
25 5vyz:C 1083 275 0.1827 0.0914 0.3600 1.61e-36 5vyw:A, 5vyw:B, 5vyw:C, 5vz0:C
26 5vyz:C 1083 151 0.0812 0.0406 0.2914 1.23e-04 5vyw:A, 5vyw:B, 5vyw:C, 5vz0:C
27 3jzf:A 380 285 0.1679 0.2395 0.3193 3.90e-36
28 3jzf:A 380 145 0.0738 0.1053 0.2759 1.50e-12
29 4qsh:C 1081 274 0.1697 0.0851 0.3358 1.92e-35 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
30 4qsh:C 1081 146 0.0775 0.0389 0.2877 1.27e-09 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
31 2qf7:A 1076 280 0.1697 0.0855 0.3286 2.04e-35 3tw6:A
32 2qf7:A 1076 150 0.0812 0.0409 0.2933 2.54e-08 3tw6:A
33 3va7:A 1130 265 0.1624 0.0779 0.3321 1.53e-32
34 3va7:A 1130 141 0.0756 0.0363 0.2908 1.75e-12
35 8jxn:J 541 277 0.1624 0.1627 0.3177 6.87e-32
36 8jxn:J 541 62 0.0424 0.0425 0.3710 0.003
37 3bg5:B 1074 271 0.1568 0.0791 0.3137 1.41e-31 3bg5:D, 8gk8:C, 3hb9:B, 3hb9:D, 3hbl:B, 3hbl:D, 4hnt:B, 4hnt:D, 4hnu:B, 4hnu:D, 4hnv:D, 3ho8:A, 3ho8:C, 3ho8:B
38 3bg5:B 1074 144 0.0775 0.0391 0.2917 1.50e-09 3bg5:D, 8gk8:C, 3hb9:B, 3hb9:D, 3hbl:B, 3hbl:D, 4hnt:B, 4hnt:D, 4hnu:B, 4hnu:D, 4hnv:D, 3ho8:A, 3ho8:C, 3ho8:B
39 3ho8:D 934 271 0.1568 0.0910 0.3137 1.86e-31
40 3ho8:D 934 144 0.0775 0.0450 0.2917 1.17e-09
41 4hnv:B 1033 256 0.1550 0.0813 0.3281 1.51e-29 8gk8:D
42 4hnv:B 1033 144 0.0756 0.0397 0.2847 8.43e-09 8gk8:D
43 3n6r:A 591 256 0.1531 0.1404 0.3242 1.90e-29 3n6r:C, 3n6r:E
44 3n6r:A 591 143 0.0867 0.0795 0.3287 5.83e-14 3n6r:C, 3n6r:E
45 8hz5:A 350 247 0.1587 0.2457 0.3482 7.96e-28
46 8hz5:A 350 152 0.0812 0.1257 0.2895 1.41e-11
47 5dou:D 1430 273 0.1033 0.0392 0.2051 4.01e-07 5dou:A, 5dou:B, 5dou:C, 6w2j:A
48 1bxr:A 1073 195 0.0720 0.0363 0.2000 6.80e-04 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G
49 1bxr:A 1073 180 0.0683 0.0345 0.2056 0.16 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G
50 8evy:B 317 195 0.0793 0.1356 0.2205 0.055 8evy:A, 8evy:C, 8evz:A, 8evz:B, 8evz:C
51 6uel:A 1333 90 0.0351 0.0143 0.2111 0.33 6uel:B
52 6w2j:B 1364 90 0.0351 0.0139 0.2111 0.35
53 7lgm:A 719 27 0.0203 0.0153 0.4074 0.85 7lgm:B
54 4do4:B 400 117 0.0572 0.0775 0.2650 0.91 4do4:A, 4do5:A, 4do5:B, 4do6:A, 4do6:B, 3h55:A, 3h55:B, 3igu:A, 3igu:B
55 4c5a:A 306 101 0.0461 0.0817 0.2475 1.9 4c5a:B, 4c5b:A, 4c5b:B, 4c5c:A, 4c5c:B, 2dln:A, 1iov:A, 1iow:A
56 6bwj:B 617 32 0.0240 0.0211 0.4062 5.0 6bwj:A, 6oo3:A, 6oo3:B, 6oo3:C, 6oo3:D, 6oo4:A, 6oo4:D, 6oo4:B, 6oo4:C, 6oo5:A, 6oo5:B, 6oo5:C, 6oo5:D, 6oo7:A, 6oo7:B, 6oo7:C, 6oo7:D
57 4z67:A 309 72 0.0351 0.0615 0.2639 8.8 6e13:A, 3jxp:A, 1xto:A, 4z5y:A, 4z5z:A, 4z60:A, 4z6x:A
58 3r5x:D 306 31 0.0166 0.0294 0.2903 9.8 3r5x:A, 3r5x:B
59 6bq3:A 292 55 0.0369 0.0685 0.3636 9.9 6bq3:B, 6bq4:A, 6bq4:B, 6bq5:A, 6bq5:B, 6bq6:A, 6bq6:B, 6bq7:A, 6bq7:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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