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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASS
ENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKE
EILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSR
PPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKV
KGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLPPS

The query sequence (length=364) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hg1:A 371 366 0.9753 0.9569 0.9699 0.0 4by3:A, 4c6c:A, 4c6d:A, 4c6e:A, 4c6f:A, 4c6i:A, 4c6j:A, 4c6k:A, 4c6l:A, 4c6m:A, 4c6n:A, 4c6o:A, 4c6p:A, 4c6q:A, 8gvz:A, 8gw0:A, 6hfd:A, 6hfe:A, 6hff:A, 6hfh:A, 6hfi:A, 6hfj:A, 6hfk:A, 6hfl:A, 6hfn:A, 6hfp:A, 6hfq:A, 6hfr:A, 6hfs:A, 6hfu:A, 6hg2:A, 6hg3:A, 8pbe:A, 8pbg:A, 8pbh:A, 8pbi:A, 8pbj:A, 8pbk:A, 8pbm:A, 8pbn:A, 8pbp:A, 8pbq:A, 8pbr:A, 8pbs:A, 8pbt:A, 8pbu:A, 5ynz:A
2 7uof:A 423 370 0.3159 0.2719 0.3108 1.70e-48
3 3mpg:A 426 382 0.3462 0.2958 0.3298 1.49e-46 3mpg:B, 4yiw:A, 4yiw:B
4 3gri:B 423 375 0.3407 0.2931 0.3307 2.20e-46 3gri:A
5 4bjh:A 422 377 0.3132 0.2701 0.3024 1.84e-41 3d6n:A
6 6gdd:A 375 361 0.3077 0.2987 0.3102 4.61e-41 6gde:A, 6gdf:A, 1xrf:A, 1xrt:A, 1xrt:B
7 3hm7:B 437 383 0.2967 0.2471 0.2820 2.12e-39 3hm7:A, 3hm7:C, 3hm7:D, 3hm7:E, 3hm7:F
8 2z00:A 426 366 0.3324 0.2840 0.3306 8.34e-36
9 2gwn:A 451 384 0.2995 0.2417 0.2839 1.35e-33
10 1gkr:A 451 402 0.3049 0.2461 0.2761 6.63e-31 1gkr:B, 1gkr:C, 1gkr:D
11 8hfd:A 452 387 0.2555 0.2058 0.2403 3.52e-27 3e74:B, 8hfd:B, 8hfd:C, 8hfd:D
12 4tqt:D 481 414 0.2995 0.2266 0.2633 5.66e-26 4tqt:A, 4tqt:B, 4tqt:C, 4tqt:E, 4tqt:F
13 3e74:A 429 374 0.2445 0.2075 0.2380 2.96e-22 3e74:C, 3e74:D
14 1nfg:A 457 243 0.1923 0.1532 0.2881 1.07e-21 1nfg:B, 1nfg:C, 1nfg:D
15 1gkp:A 458 407 0.2912 0.2314 0.2604 1.35e-21 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
16 3dc8:A 483 413 0.2885 0.2174 0.2542 3.74e-20 3dc8:B
17 5e5c:C 479 415 0.2857 0.2171 0.2506 1.23e-16 6ajd:A, 6ajd:B, 7e3u:A, 7e3u:B, 5e5c:A, 6klk:A, 6klk:B, 8wq9:A, 8wq9:B, 5ykd:A, 5ykd:B, 5ykd:C, 5ykd:D
18 1k1d:A 460 412 0.2665 0.2109 0.2354 4.34e-15 1k1d:B, 1k1d:C, 1k1d:D, 1k1d:E, 1k1d:F, 1k1d:G, 1k1d:H
19 3sfw:A 461 405 0.2747 0.2169 0.2469 1.19e-14 3sfw:B
20 4kir:A 460 405 0.2720 0.2152 0.2444 1.69e-14 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
21 2fty:A 532 459 0.2747 0.1880 0.2179 1.36e-10 2fty:B, 2fty:C, 2fty:D, 2fvk:A, 2fvk:B, 2fvk:C, 2fvk:D, 2fvm:A, 2fvm:B, 2fvm:C, 2fvm:D
22 4gz7:A 492 411 0.2418 0.1789 0.2141 1.07e-08 4h00:A, 4h01:A, 4lcq:A, 4lcr:A, 4lcs:A
23 4b92:A 476 424 0.2610 0.1996 0.2241 3.44e-08 4b92:B
24 2vr2:A 478 420 0.2500 0.1904 0.2167 6.78e-06
25 4cns:D 479 72 0.0797 0.0605 0.4028 8.62e-06 4cns:A, 4cns:B, 4cns:C
26 4cns:D 479 117 0.0769 0.0585 0.2393 0.041 4cns:A, 4cns:B, 4cns:C
27 2ftw:A 484 74 0.0714 0.0537 0.3514 4.86e-04
28 8olx:B 836 177 0.1044 0.0455 0.2147 1.2 8om5:B, 8om9:B
29 2vqa:A 356 104 0.0852 0.0871 0.2981 1.8 2vqa:B, 2vqa:C
30 2kfy:A 102 55 0.0604 0.2157 0.4000 2.8
31 5zcr:A 725 25 0.0275 0.0138 0.4000 3.9 5zcr:B
32 2c8s:A 149 58 0.0357 0.0872 0.2241 7.6
33 2z72:A 338 43 0.0412 0.0444 0.3488 7.9 1v73:A, 2zbm:A
34 6bn5:B 448 28 0.0357 0.0290 0.4643 8.5
35 8fvy:O 139 28 0.0302 0.0791 0.3929 8.5 8br8:SQ, 8brm:SQ, 8bsi:SQ, 8bsj:SQ, 8btd:SQ, 8btr:SQ, 8g4s:O, 7pwf:O, 7pwo:O1
36 1a0s:P 413 24 0.0330 0.0291 0.5000 8.8 1a0s:Q, 1a0s:R, 1a0t:P, 1a0t:R, 1a0t:Q, 1oh2:P, 1oh2:R, 1oh2:Q

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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