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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KLRELVARSRSIRRFDEHVAVNDATLRDLVELVCYTPSAANRQLLRFLPVTGADMSDKVFPCLKWAGYLEDWPGPEPGER
PAAALVMLCRNEDLPGAACDSGIAAQTIMLGAAEKELGGCIVAAIDRERLMASLGIPDAWTVLLVIALGKPAETVVIDQI
KPGDDIRYWRDKHGIHHVPKRQVDELLVTAEQLRE

The query sequence (length=195) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2r01:A 195 195 1.0000 1.0000 1.0000 8.10e-143
2 8cqt:B 164 150 0.2256 0.2683 0.2933 2.39e-09 8cqt:A
3 4dn2:A 191 165 0.2564 0.2618 0.3030 2.46e-09 4dn2:B
4 3qdl:A 178 135 0.1795 0.1966 0.2593 1.63e-05 3qdl:B, 3qdl:C, 3qdl:D
5 4g8s:A 182 163 0.2256 0.2418 0.2699 1.62e-04 4g8s:B
6 1bkj:A 230 177 0.2103 0.1783 0.2316 5.62e-04 1bkj:B, 2bkj:A, 2bkj:B
7 3ge6:A 210 64 0.0923 0.0857 0.2812 0.005 3ge6:B
8 5uu6:C 236 60 0.0974 0.0805 0.3167 0.013 5uu6:A, 5uu6:B, 5uu6:D
9 5j6c:A 173 160 0.1846 0.2081 0.2250 0.014 5j6c:B
10 7p18:A 558 69 0.1128 0.0394 0.3188 0.019 7p18:B
11 3ge5:A 176 162 0.2051 0.2273 0.2469 0.026 3ge5:B
12 4eo3:A 321 129 0.1590 0.0966 0.2403 0.034 4eo3:B
13 3bem:B 210 182 0.1897 0.1762 0.2033 0.052 3bem:A
14 3gbh:B 213 202 0.2051 0.1878 0.1980 0.054 3gbh:A, 3gbh:C, 3gbh:D
15 3gfa:A 197 46 0.0718 0.0711 0.3043 0.059 3gfa:B
16 3e39:A 175 51 0.0923 0.1029 0.3529 0.11 3e39:B
17 3e10:B 167 166 0.2051 0.2395 0.2410 0.19 3e10:A
18 3gag:A 206 171 0.1641 0.1553 0.1871 0.23 3gag:B, 3gag:C, 3gag:D
19 3n2s:A 248 55 0.0923 0.0726 0.3273 0.26 3n2s:B, 3n2s:C, 3n2s:D
20 1nox:A 200 192 0.2615 0.2550 0.2656 0.56
21 3gr3:A 226 186 0.2103 0.1814 0.2204 0.79 3gr3:B
22 3eo7:A 487 52 0.0769 0.0308 0.2885 0.82
23 2fre:A 200 162 0.1949 0.1900 0.2346 1.0 2fre:B
24 8uc3:A 180 47 0.0667 0.0722 0.2766 1.4 8uc3:B
25 3ek3:A 187 178 0.2000 0.2086 0.2191 1.9
26 1g0d:A 666 77 0.1231 0.0360 0.3117 2.2
27 8ouo:B 625 37 0.0564 0.0176 0.2973 2.7 6nq0:A, 6nq0:B, 6nq2:A, 6nq2:B
28 6os6:A 362 46 0.0974 0.0525 0.4130 2.8 6os5:A, 6os5:B, 6os5:C
29 4bn9:A 191 51 0.0821 0.0838 0.3137 3.9 4bn6:A, 4bn7:A, 4bn8:A, 4bnb:A, 2wqf:A
30 4qlx:A 217 49 0.0718 0.0645 0.2857 4.2 4qlx:B, 4qly:A, 4qly:B, 4qly:C, 4qly:D
31 5hdj:B 248 67 0.0974 0.0766 0.2836 4.6 5hdj:A
32 2wzv:B 223 66 0.0923 0.0807 0.2727 5.6 2wzv:A, 2wzw:A, 2wzw:B
33 4b4o:A 295 35 0.0513 0.0339 0.2857 6.0 4b4o:B, 4b4o:C, 4b4o:D, 4b4o:E, 4b4o:F, 4b4o:G, 4b4o:H
34 1ywq:A 199 48 0.0564 0.0553 0.2292 7.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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