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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFS
TQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHN
LYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITE
IDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKP
QVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLN
VKLTKLTEKQAQYLGMPINGPFKPDHYRY

The query sequence (length=429) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1a7a:A 431 429 0.9674 0.9629 0.9674 0.0 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
2 3h9u:C 435 434 0.7366 0.7264 0.7281 0.0 3h9u:A, 3h9u:B, 3h9u:D
3 3g1u:C 424 428 0.7086 0.7170 0.7103 0.0 3g1u:A, 3g1u:B, 3g1u:D
4 6aph:A 432 431 0.6876 0.6829 0.6845 0.0
5 6gbn:B 435 431 0.6620 0.6529 0.6589 0.0 6gbn:A, 6gbn:C, 6gbn:D
6 3d64:A 462 462 0.6480 0.6017 0.6017 0.0 3d64:B, 3glq:A, 3glq:B
7 6uk3:A 475 465 0.6457 0.5832 0.5957 0.0 6uk3:C, 6uk3:B, 6uk3:D
8 3ce6:A 486 477 0.6270 0.5535 0.5639 0.0 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
9 3n58:B 461 460 0.6317 0.5879 0.5891 6.99e-179 3n58:A, 3n58:C, 3n58:D
10 5v96:A 467 467 0.6340 0.5824 0.5824 1.52e-178 5v96:B, 5v96:C, 5v96:D
11 3ond:B 488 472 0.6317 0.5553 0.5742 2.61e-177 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
12 5m5k:C 471 467 0.6340 0.5775 0.5824 2.10e-176 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
13 8cfu:A 467 462 0.6177 0.5675 0.5736 4.15e-167 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
14 1v8b:A 476 473 0.5804 0.5231 0.5264 6.29e-167 1v8b:B, 1v8b:C, 1v8b:D
15 3gvp:A 433 423 0.5012 0.4965 0.5083 9.11e-156 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
16 5jpi:A 496 495 0.5478 0.4738 0.4747 4.71e-148 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
17 7r39:A 412 410 0.4545 0.4733 0.4756 5.94e-122 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 411 0.4522 0.4608 0.4720 3.39e-116 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7r3a:A 411 409 0.4196 0.4380 0.4401 1.13e-106 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
20 7o5l:A 417 412 0.4289 0.4412 0.4466 1.14e-106 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
21 3x2f:A 406 389 0.3986 0.4212 0.4396 1.64e-101 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 1j49:A 332 95 0.0559 0.0723 0.2526 0.007 1j49:B
23 8ep7:C 328 63 0.0466 0.0610 0.3175 0.030 8ep7:A, 8ep7:B
24 6bii:A 332 105 0.0606 0.0783 0.2476 0.031 6bii:B
25 2dld:A 337 92 0.0536 0.0682 0.2500 0.037 2dld:B
26 7pci:A 345 107 0.0769 0.0957 0.3084 0.050 7pcc:A, 7pcc:B, 7pce:A, 7pcg:A, 7pcg:B, 7pcl:A, 7pcl:B, 7pcm:A, 7pcm:B, 7pcn:A, 7pcn:B, 7pco:A, 7pco:B, 7pct:A, 7pct:B
27 5aov:A 334 104 0.0676 0.0868 0.2788 0.058
28 6jcz:C 331 61 0.0466 0.0604 0.3279 0.092 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
29 7loz:B 390 60 0.0513 0.0564 0.3667 0.18 7ll3:A, 7ll3:B, 7lnn:A, 7lnn:B, 7lo2:A, 7lo2:B, 7lo2:C, 7lo2:D, 7loo:A, 7loo:Q, 7loo:B, 7loo:R, 7low:A, 7low:B, 7loz:A, 1mxa:A, 1mxb:A, 1mxc:A, 1p7l:A, 1p7l:B, 1p7l:C, 1p7l:D, 7r2w:A, 1rg9:A, 1rg9:B, 1rg9:C, 1rg9:D, 1xra:A
30 6ih6:A 330 63 0.0443 0.0576 0.3016 0.37 6ih3:A, 6ih5:B, 6ih6:B
31 6bul:B 327 66 0.0559 0.0734 0.3636 0.41 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
32 6jx2:B 327 58 0.0466 0.0612 0.3448 0.47 6jx2:A, 6jx2:C, 6jx2:D
33 6umq:A 415 37 0.0303 0.0313 0.3514 0.55 6umq:B
34 4xdy:A 331 70 0.0466 0.0604 0.2857 0.65 4xdy:B
35 5idy:B 264 89 0.0629 0.1023 0.3034 0.90 5idy:A, 5vps:A
36 6l2i:A 324 70 0.0606 0.0802 0.3714 0.90 6l2i:B, 6l2z:A, 6l2z:B
37 4prl:A 330 107 0.0699 0.0909 0.2804 0.92 4prl:B
38 2gcg:A 324 91 0.0583 0.0772 0.2747 1.1 2gcg:B, 2gcg:C, 2gcg:D
39 4cuk:A 330 96 0.0583 0.0758 0.2604 1.2 4cuk:D
40 5mh5:A 308 95 0.0536 0.0747 0.2421 1.2 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
41 4tsk:A 333 63 0.0466 0.0601 0.3175 1.4
42 3dc2:A 526 55 0.0466 0.0380 0.3636 2.4 3dc2:B, 3ddn:B
43 8q66:A 271 68 0.0466 0.0738 0.2941 2.9
44 2buj:A 291 100 0.0466 0.0687 0.2000 2.9 2buj:B
45 2ff4:A 379 46 0.0373 0.0422 0.3478 4.2 2ff4:B
46 8gxf:B 187 40 0.0420 0.0963 0.4500 4.6 8gxf:A, 8gxf:C, 8gxf:D
47 3d3w:A 244 34 0.0326 0.0574 0.4118 5.0 3d3w:B, 1pr9:A, 1pr9:B, 1wnt:A, 1wnt:B, 1wnt:C, 1wnt:D
48 1g0o:C 281 175 0.1049 0.1601 0.2571 5.5 1doh:A, 1doh:B, 1g0n:A, 1g0n:B, 1g0o:A, 1g0o:B, 1g0o:D, 1ybv:A, 1ybv:B
49 1dxy:A 330 85 0.0490 0.0636 0.2471 6.8
50 5va8:A 261 40 0.0420 0.0690 0.4500 7.6 5va8:B, 5va8:C, 5va8:D
51 1qp8:A 301 137 0.0816 0.1163 0.2555 7.7 1qp8:B
52 8hr6:A 359 53 0.0396 0.0474 0.3208 8.1 8hr6:B
53 1bgv:A 449 71 0.0466 0.0445 0.2817 9.4
54 1v9l:A 418 54 0.0420 0.0431 0.3333 9.8 1v9l:B, 1v9l:C, 1v9l:D, 1v9l:E, 1v9l:F
55 3aoe:B 424 58 0.0373 0.0377 0.2759 9.8 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
56 2ekl:A 312 99 0.0536 0.0737 0.2323 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218