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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRILYL
QEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMI
KFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLI
ALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMI
KRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQ
RTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVV
DKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVK
QLKEDYFKKIEEFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHL
FDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVDSLHEHIAN
LAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLK
SKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDFYSNIMNFFKLIETNGETGEIVWDKGR
DFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLK
SVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYL
ASHYEPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAA
FKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG

The query sequence (length=1163) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4oo8:D 1163 1163 1.0000 1.0000 1.0000 0.0
2 7z4g:B 1188 1189 0.9957 0.9747 0.9739 0.0 7zo1:B
3 7z4d:B 1259 1257 0.9966 0.9206 0.9220 0.0
4 8t6y:A 1148 1169 0.9690 0.9817 0.9641 0.0 8t6o:A, 8t79:A
5 8t6t:A 1168 1189 0.9690 0.9649 0.9479 0.0 8t7s:G
6 4zt9:C 1160 1202 0.9604 0.9629 0.9293 0.0
7 7s4v:A 1122 1168 0.9570 0.9920 0.9529 0.0 6o0x:A, 8t6p:A
8 7s4u:A 1092 1168 0.9329 0.9936 0.9289 0.0
9 7z4d:E 1166 1223 0.9458 0.9434 0.8994 0.0
10 8t76:A 1088 1168 0.9183 0.9816 0.9144 0.0
11 8t6s:A 962 1170 0.7704 0.9314 0.7658 0.0
12 5y36:A 1368 763 0.6509 0.5534 0.9921 0.0 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
13 5y36:A 1368 449 0.3474 0.2953 0.8998 0.0 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
14 8t77:A 1025 948 0.6905 0.7834 0.8470 0.0
15 8t77:A 1025 227 0.1883 0.2137 0.9648 5.59e-125
16 7z4j:B 1345 763 0.6500 0.5621 0.9908 0.0 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
17 7z4j:B 1345 429 0.3474 0.3004 0.9417 0.0 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
18 4oo8:A 1301 775 0.6500 0.5811 0.9755 0.0 4zt0:C
19 4oo8:A 1301 418 0.3388 0.3028 0.9426 0.0 4zt0:C
20 5b2r:B 1319 792 0.6509 0.5739 0.9558 0.0 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
21 5b2r:B 1319 425 0.3439 0.3033 0.9412 0.0 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
22 8kag:B 1346 760 0.6406 0.5535 0.9803 0.0 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
23 8kag:B 1346 449 0.3474 0.3001 0.8998 0.0 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
24 8t7s:A 1312 759 0.6225 0.5518 0.9539 0.0
25 8t7s:A 1312 432 0.3379 0.2995 0.9097 0.0
26 5xbl:A 1320 759 0.6174 0.5439 0.9460 0.0
27 5xbl:A 1320 449 0.3474 0.3061 0.8998 0.0
28 6o0z:A 1288 760 0.6174 0.5575 0.9447 0.0
29 6o0z:A 1288 433 0.3457 0.3121 0.9284 0.0
30 8t6x:A 1278 759 0.5907 0.5376 0.9051 0.0
31 8t6x:A 1278 436 0.3388 0.3083 0.9037 0.0
32 4cmq:B 1168 760 0.5658 0.5634 0.8658 0.0 4cmp:B, 4cmq:A
33 4cmq:B 1168 431 0.2966 0.2954 0.8005 0.0 4cmp:B, 4cmq:A
34 8pj9:A 1051 889 0.4213 0.4662 0.5512 0.0
35 8pj9:A 1051 193 0.1169 0.1294 0.7047 1.36e-66
36 6o0y:A 1146 451 0.3861 0.3918 0.9956 0.0
37 6o0y:A 1146 410 0.3173 0.3220 0.9000 0.0
38 6o0y:A 1146 172 0.1462 0.1483 0.9884 1.16e-103
39 8t78:A 863 590 0.3947 0.5319 0.7780 0.0
40 8t78:A 863 218 0.1840 0.2480 0.9817 1.66e-140
41 8t78:A 863 216 0.1574 0.2121 0.8472 1.30e-98
42 7s37:P 1033 445 0.3543 0.3988 0.9258 0.0 7s3h:P
43 7s37:P 1033 449 0.3199 0.3601 0.8285 0.0 7s3h:P
44 7s37:P 1033 60 0.0447 0.0503 0.8667 5.52e-22 7s3h:P
45 7vw3:A 1052 222 0.0499 0.0551 0.2613 1.01e-09 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
46 7vw3:A 1052 75 0.0206 0.0228 0.3200 8.3 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
47 8x5v:A 892 394 0.0800 0.1043 0.2360 1.97e-09
48 8uza:A 910 410 0.0860 0.1099 0.2439 2.58e-09 8uzb:A
49 8uza:A 910 18 0.0112 0.0143 0.7222 0.47 8uzb:A
50 8jtr:A 1056 342 0.0731 0.0805 0.2485 4.60e-05
51 8jtr:A 1056 18 0.0103 0.0114 0.6667 2.8
52 8jtj:A 1042 349 0.0731 0.0816 0.2436 7.25e-05
53 8jtj:A 1042 18 0.0103 0.0115 0.6667 2.8
54 8wr4:B 1442 213 0.0507 0.0409 0.2770 0.025
55 8wr4:B 1442 133 0.0292 0.0236 0.2556 6.4
56 8wmm:B 1212 213 0.0507 0.0487 0.2770 0.026 8iyq:A, 8wmh:A, 8wmm:A, 8wmn:A, 8wmn:B, 8wr4:A
57 6m0w:A 1032 362 0.0800 0.0901 0.2569 0.038 6m0v:A, 6m0x:A
58 6rj9:C 836 239 0.0533 0.0742 0.2594 0.25 6rjd:C
59 6rja:C 815 361 0.0739 0.1055 0.2382 0.55 6rja:F, 6rjg:C
60 6jdv:A 1036 95 0.0206 0.0232 0.2526 1.1 6kc8:A
61 2pla:A 343 89 0.0206 0.0700 0.2697 1.2 2pla:B
62 7zjm:A 220 80 0.0224 0.1182 0.3250 1.3 6atg:B, 6atg:C
63 6jdq:A 1069 119 0.0275 0.0299 0.2689 2.8 6je4:A, 6je4:E, 6je4:K, 6je9:A
64 8hnv:A 745 25 0.0120 0.0188 0.5600 4.6
65 5h60:A 304 93 0.0215 0.0822 0.2688 4.6 7ym5:A
66 4j2o:C 316 53 0.0146 0.0538 0.3208 4.9 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
67 8ewy:A 1049 51 0.0181 0.0200 0.4118 5.5 6aah:A, 6aah:B, 6bbu:A, 6c7y:A, 6dbn:A, 5e1e:A, 5e1e:B, 4e4l:A, 4e4l:E, 4e4l:B, 4e4l:D, 4e4n:A, 4e4n:B, 4e5w:A, 4e5w:B, 4ehz:A, 4ehz:B, 4ehz:C, 4ehz:D, 4ei4:A, 4ei4:B, 6elr:A, 6elr:B, 8ewy:B, 3eyg:A, 3eyh:A, 4fk6:A, 4fk6:B, 6ggh:A, 6ggh:B, 5hx8:A, 5hx8:B, 6hzu:A, 6hzu:B, 4i5c:A, 4i5c:B, 4ivb:A, 4ivb:B, 4ivc:A, 4ivc:B, 4ivd:A, 4ivd:B, 4k6z:A, 4k77:A, 4k77:B, 5khw:A, 5khw:B, 5khx:A, 6n77:A, 6n77:B, 6n78:A, 6n79:A, 6n7a:A, 6n7a:B, 6n7b:A, 6n7c:A, 6n7c:B, 6n7d:A, 6rsb:A, 6rsb:B, 6rsc:A, 6rsc:B, 6rsd:A, 6rsd:B, 6rse:A, 6rse:B, 6rsh:A, 6rsh:B, 6sm8:A, 6sm8:B, 6smb:A, 6smb:B, 7t6f:A, 7t6f:B, 6tpe:A, 6tpe:B, 6tpf:A, 6tpf:B, 6w8l:A, 5wo4:A, 5wo4:B
68 6je4:O 1049 25 0.0120 0.0133 0.5600 5.9 8hj4:A, 8ja0:A, 6je9:C
69 6jfu:A 884 25 0.0120 0.0158 0.5600 6.1
70 3x1l:D 331 126 0.0275 0.0967 0.2540 6.2 3x1l:C, 3x1l:E
71 6je3:A 858 25 0.0120 0.0163 0.5600 6.2
72 6stt:A 178 101 0.0232 0.1517 0.2673 6.6 6stt:B
73 4gyi:A 339 115 0.0249 0.0855 0.2522 7.8
74 6l4t:7 188 58 0.0181 0.1117 0.3621 8.7 6l4u:7, 6ly5:E
75 4ozv:A 333 50 0.0138 0.0480 0.3200 9.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218