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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKYNVCIVGGGSTYTPGFLKSFVRLQNEFPMEKLVLFDIDAERQQPIGEFGKILFSERFPELDFSYTTDPAEAYKDMDFI
FMQMRAGGLPMRREDEHISLHLGRIGQETCGAGGMAYGLRSCVDMIESIHQIRQYSPNAWILNYSNPAAIVAEALRREFP
DDNRILNICDQPENIMRSVSRLLNVSWEDLDPVYFGLNHYGWFTHVYDRKTGEDLLPEIKKIIKEKGFLPQDAEQRDQSW
LDTYGFVQTMMEDFPDFLPNTYDGYYLYPDYKFSHLNPDYTRADEVIDGREKRVFAECREVIARGELDAHAEMMIKVAEA
IAYNKNTRFIVIVKNEGAIANMQDDAMVELVCELGINGPRRMAVGNIPQFYLGLLVQQVSSEKLLVDAYYEHSYQKALEA
FTLNRLINDAKKAREILDAMIEVNKGMWPELK

The query sequence (length=432) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6vc6:B 440 440 1.0000 0.9818 0.9818 0.0 6vc6:A, 6vc6:C, 6vc6:D
2 6dvv:A 435 439 0.4653 0.4621 0.4579 1.01e-139 6dux:A, 6dux:B, 6dvv:B
3 1u8x:X 436 440 0.4537 0.4495 0.4455 2.50e-132
4 6wbt:A 442 444 0.4444 0.4344 0.4324 2.00e-122 6wbt:B, 6wbt:C, 6wbt:D
5 5c3m:B 411 439 0.3009 0.3163 0.2961 2.53e-52 5c3m:A, 5c3m:C, 5c3m:D
6 1up7:A 414 435 0.2847 0.2971 0.2828 2.59e-47 1up6:A, 1up6:C, 1up6:G, 1up7:B, 1up7:C, 1up7:D, 1up7:E, 1up7:F, 1up7:G, 1up7:H
7 3fef:A 434 446 0.2431 0.2419 0.2354 8.93e-18 3fef:B, 3fef:C, 3fef:D
8 1vjt:A 471 291 0.1620 0.1486 0.2405 2.51e-07 7br4:A, 7brf:A, 7ctl:A, 7ctm:A, 6kcx:A, 3u95:A, 3u95:B, 3u95:C, 3u95:D, 3u95:E, 3u95:F
9 1obb:A 478 405 0.2153 0.1946 0.2296 4.36e-07 1obb:B
10 4a7p:A 429 38 0.0394 0.0396 0.4474 0.10 4a7p:B
11 2wsi:A 285 75 0.0556 0.0842 0.3200 0.19
12 1xrk:B 121 89 0.0556 0.1983 0.2697 0.22 1xrk:A, 2zhp:A, 2zhp:B
13 6ct6:B 331 96 0.0509 0.0665 0.2292 1.0 6ct6:A
14 5fzo:A 339 56 0.0417 0.0531 0.3214 1.5 5fzo:B, 2ypd:A, 2ypd:B
15 2iii:A 120 50 0.0370 0.1333 0.3200 5.2
16 2dwu:B 266 57 0.0370 0.0602 0.2807 6.0 2dwu:A, 2dwu:C
17 6euo:C 354 116 0.0648 0.0791 0.2414 6.6 6euo:A, 6euo:B, 6euo:D, 6eur:A, 6eur:C, 6eur:D, 6exf:A, 6exf:C, 6exf:D, 6exh:A, 6exh:B, 6exh:C, 6exh:D, 6f9p:A, 6f9p:C, 6f9p:D
18 3ruq:A 516 119 0.0671 0.0562 0.2437 7.2 3kfb:A, 3kfb:B, 3kfb:C, 3kfb:D, 3kfb:E, 3kfb:F, 3kfb:G, 3kfb:H, 7rak:U, 7rak:A, 7rak:B, 7rak:C, 7rak:D, 7rak:E, 7rak:F, 7rak:G, 7rak:H, 7rak:I, 7rak:J, 7rak:K, 7rak:L, 7rak:M, 7rak:N, 7rak:O, 3ruq:B, 3ruq:C, 3ruq:D, 3rus:A, 3rus:B, 3rus:C, 3rus:D, 3ruv:A, 3ruv:B, 3ruv:C, 3ruv:D, 3ruw:A, 3ruw:B, 3ruw:C, 3ruw:D
19 3kfe:A 487 119 0.0671 0.0595 0.2437 8.2 3kfe:B, 3kfe:C, 3kfe:D, 3kfe:E, 3kfe:F, 3kfe:G, 3kfe:H, 3kfk:A, 3kfk:B, 3kfk:C, 3kfk:D, 5w74:A, 5w74:B, 5w74:C, 5w74:D, 5w74:E, 5w74:F, 5w74:G, 5w74:H
20 7ml3:7 548 67 0.0370 0.0292 0.2388 9.0
21 7k04:7 638 67 0.0370 0.0251 0.2388 9.9 5fmf:1, 7m2u:7, 7ml0:7, 7ml1:7, 7ml2:7, 5sva:Z
22 7zsa:7 616 67 0.0370 0.0260 0.2388 10.0 8cen:7, 8ceo:7, 7o4i:7, 7o4j:7, 7o4k:7, 7o4l:7, 7o72:7, 7o73:7, 7o75:7, 7zs9:7, 7zsb:7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218