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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKSIYVAYTGGTIGMEFHRPEMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALSFM
LENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNRTTKAHADGFDAFASPNLPPLLEAG
IHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIYPGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRG
IVVVNLTQCMSGKVNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGELTP

The query sequence (length=304) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6nxc:B 336 326 0.9967 0.9018 0.9294 0.0 2him:A, 2him:B, 2him:C, 2him:D, 6nxc:A, 6nxc:C, 6nxc:D, 6nxd:A, 6nxd:B, 6nxd:C, 6nxd:D, 2p2n:A, 2p2n:B, 2p2n:C, 2p2n:D
2 7r6b:B 301 324 0.7533 0.7608 0.7068 5.78e-154
3 5dnd:D 357 352 0.4737 0.4034 0.4091 6.62e-85 5dnc:A, 5dnc:B, 5dnc:C, 5dnc:D, 5dnd:A, 5dnd:B, 5dnd:C, 5dne:A, 5dne:B, 5dne:C, 5dne:D, 4r8l:A, 4r8l:B, 4r8l:C, 4r8l:D
4 5ot0:A 328 280 0.3421 0.3171 0.3714 3.26e-46 5ot0:B, 5ot0:C, 5ot0:D, 5ot0:E, 5ot0:F
5 4q0m:A 327 278 0.3355 0.3119 0.3669 4.33e-44 5b5u:A, 5b74:B, 4nje:A
6 1zq1:A 437 287 0.3026 0.2105 0.3206 1.12e-40 1zq1:B
7 2wlt:A 326 263 0.2303 0.2147 0.2662 5.63e-17 2wt4:A
8 6pa3:A 334 312 0.2796 0.2545 0.2724 2.84e-16 3eca:A, 3eca:B, 3eca:C, 3eca:D, 8ecd:A, 8ecd:B, 8ecd:C, 8ecd:D, 8ece:A, 8ece:B, 8ece:C, 8ece:D, 6eok:B, 6eok:C, 6eok:D, 1ho3:A, 1ho3:B, 1jaz:A, 1jaz:B, 7m11:A, 7m11:B, 7m11:C, 7m11:D, 5mq5:A, 5mq5:C, 5mq5:B, 5mq5:D, 1nns:A, 1nns:B, 6pa2:A, 6pa2:C, 6pa2:B, 6pa2:D, 6pa3:B, 6pa3:C, 6pa3:D, 6pa4:A, 6pa4:B, 6pa4:C, 6pa4:D, 6pa5:A, 6pa5:B, 6pa5:C, 6pa5:D, 6pa5:E, 6pa5:F, 6pa5:G, 6pa5:H, 6pa6:A, 6pa6:B, 6pa6:C, 6pa6:D, 6pa8:A, 6pa8:B, 6pa8:C, 6pa8:D, 6pa9:A, 6pa9:B, 6paa:A, 6paa:B, 6paa:C, 6paa:D, 6pab:A, 6pab:B, 6pab:C, 6pab:D, 6pac:A, 6pac:B, 6pac:C, 6pac:D, 7r5q:A, 7r5q:B, 7r5q:C, 7r5q:D, 6uog:A, 6uog:B, 6uog:C, 6uog:D, 6uog:E, 6uog:F, 6uog:G, 6uog:H, 6uoh:A, 6uoh:B, 6v24:A, 6v24:D, 6v25:A, 6v25:B, 6v26:A, 6v26:B, 6v26:C, 6v26:D, 6v29:A, 6v29:B, 6v29:C, 6v29:D, 6v2a:A, 6v2a:B, 6v2a:C, 6v2a:D, 6v2b:A, 6v2b:B, 6v2b:C, 6v2b:D, 6v5f:A, 6v5f:D
9 8h4a:B 328 242 0.2237 0.2073 0.2810 5.60e-16 7c8q:A, 7c8q:B, 7c8x:A, 7c8x:B, 7c91:B, 7c91:A, 7cb4:B, 7cb4:A, 7cbr:A, 7cbr:B, 7cbu:A, 7cbu:B, 7cbw:A, 7cbw:B, 8h44:A, 8h44:B, 8h45:A, 8h45:B, 8h46:A, 8h46:B, 8h47:A, 8h47:B, 8h48:A, 8h48:B, 8h49:A, 8h49:B, 8h4a:A, 8h4b:A, 8h4b:B, 8h4c:A, 8h4c:B, 8h4d:A, 8h4d:B, 8h4e:A, 8h4e:B, 8h4f:A, 8h4f:B, 8h4g:A, 8h4g:B
10 5k3o:A 328 316 0.2566 0.2378 0.2468 9.41e-14 5k3o:B, 5k3o:C, 5k3o:D, 5k45:A, 5k45:B, 5k45:C, 5k45:D, 5k4g:A, 5k4g:B, 5k4g:C, 5k4g:D, 5k4h:A, 5k4h:B, 5k4h:C, 5k4h:D, 5k4h:E, 5k4h:F, 5k4h:G, 5k4h:H, 6rue:A, 6rue:B, 6rue:C, 6rue:D, 6ruf:A, 6ruf:B, 6ruf:C, 6ruf:D
11 1djo:A 330 243 0.2105 0.1939 0.2634 7.58e-12 1djo:B, 1djp:A, 1djp:B, 4pga:A, 4pga:B, 6wyw:A, 6wyw:B, 6wyw:C, 6wyw:D, 6wyx:A, 6wyx:B, 6wyx:C, 6wyx:D, 6wyy:A, 6wyy:B, 6wyy:C, 6wyy:D, 6wyz:A, 6wyz:B, 6wyz:C, 6wyz:D, 6wz4:A, 6wz4:B, 6wz4:C, 6wz4:D, 6wz6:A, 6wz6:B, 6wz6:C, 6wz6:D
12 7u6m:C 342 97 0.1086 0.0965 0.3402 3.55e-08 5f52:A, 5f52:B, 5f52:C, 5f52:D, 1hfw:A, 1hfw:B, 1hfw:C, 1hfw:D, 1hg0:A, 1hg0:B, 1hg0:C, 1hg0:D, 1hg1:A, 1hg1:B, 1hg1:C, 1hg1:D, 5hw0:A, 5hw0:B, 5hw0:C, 5hw0:D, 5i3z:A, 5i3z:B, 5i3z:C, 5i3z:D, 5i48:A, 5i48:B, 5i48:C, 5i48:D, 5i4b:A, 5i4b:B, 5i4b:C, 1jsl:A, 1jsl:B, 1jsl:C, 1jsl:D, 1jsr:A, 1jsr:B, 1jsr:C, 1jsr:D, 6pae:A, 6pae:B, 6pae:C, 6pae:D, 7u6m:A, 7u6m:B, 7u6m:D
13 2gvn:A 325 153 0.1349 0.1262 0.2680 6.64e-08 2gvn:B, 2gvn:C, 2gvn:D, 2gvn:E, 2gvn:F, 2gvn:G, 2gvn:H, 2hln:A, 2hln:B, 2hln:E, 2hln:F, 2hln:C, 2hln:D, 2hln:G, 2hln:H, 2hln:I, 2hln:J, 2hln:K, 2hln:L, 2jk0:A, 2jk0:B, 2jk0:C, 2jk0:D, 2jk0:E, 2jk0:F, 2jk0:G, 2jk0:H
14 8uou:A 169 74 0.0822 0.1479 0.3378 6.20e-05 8uou:B, 8up3:E, 8up3:F, 8up6:B, 8up6:C, 8up8:A, 8up8:B, 8up8:C
15 8x6f:D 1176 89 0.0789 0.0204 0.2697 0.78 8x6g:D
16 9cpo:A 930 41 0.0395 0.0129 0.2927 0.95
17 3jvv:C 337 38 0.0395 0.0356 0.3158 2.4 3jvv:A, 3jvv:B
18 1fx7:A 230 66 0.0789 0.1043 0.3636 2.4 1b1b:A, 1fx7:B, 1fx7:C, 1fx7:D, 2isz:A, 2isz:B, 2isz:C, 2isz:D, 2it0:A, 2it0:B, 2it0:C, 2it0:D, 1u8r:A, 1u8r:B, 1u8r:C, 1u8r:D, 1u8r:G, 1u8r:H, 1u8r:I, 1u8r:J
19 7unv:x 593 64 0.0691 0.0354 0.3281 2.6 7unq:x, 7unr:x, 7unt:x, 7unu:x, 7unw:x
20 5meh:A 438 59 0.0559 0.0388 0.2881 6.7 4ayp:A, 4ayq:A, 4ayr:A, 8b5m:A, 5ne5:A
21 5a3j:C 327 41 0.0362 0.0336 0.2683 6.8 5a3j:D, 5a3j:B, 5a3j:A, 5a3j:E, 5a3j:H, 5a3j:F, 5a3j:G, 5a3j:I, 5a3j:J, 5a3j:K, 5a4d:A, 5a4d:B, 5a4d:C, 5a4d:D, 5a4d:E, 5a4d:F, 5a4d:G, 5a4d:H
22 8em4:A 3818 23 0.0296 0.0024 0.3913 7.7 8em4:B
23 8em7:A 4378 23 0.0296 0.0021 0.3913 7.7 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
24 1sez:A 465 83 0.0691 0.0452 0.2530 8.0 1sez:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218