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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKPNVLILLFDDMRFDTFSYRNGPVSTPNIDALANEGTRFDQAMTSTGLSSPSRAAMFTGRWGHKTGLDDNVGLYHSRLS
ELSLSEGSVIKRATSIGYDVSYVGKWHLGAQGPALRGANFMWGHDKDEERNGRPFTPYQTQKNVARMNAGERDKNGEKHD
YYKTLPGTYADTVTAKEVNEGKLMLQNAAKSDKPFFGIVSFEQPHPPYRVPEPYASMYDYKDIKLPKNFGIKRKHKPMAQ
DDIWWPWHDVSHMSETDWRKAHSFYYGAIAMIDHAVGELINTAKEEGLYDDLHIILVGDQGSMLGEHNLYDKGPYAYDEL
MRMPLIIRDPSLEPKIINRQVSMLDIAPTLRQWMTLPLDGDEDGRSLLPLMKQGDSADAGKDDISLYAYEWYNGGWFGIR
AIRTPEMKFVWNPGDSRDELYDLKNDPYEITNQIDNPKYKKQLTDLVHKMAGELNRIDDPSLTKFNHHMKAFL

The query sequence (length=473) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6pt4:B 473 473 0.9979 0.9979 0.9979 0.0 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
2 7oz8:AAA 474 476 0.2812 0.2806 0.2794 8.50e-36
3 7lj2:A 507 518 0.2664 0.2485 0.2432 1.57e-33 7lha:A, 7lha:B, 7lj2:B
4 4uph:A 504 474 0.2770 0.2599 0.2764 1.72e-33 4uph:B, 4uph:C, 4uph:D
5 7ebp:A 526 531 0.2981 0.2681 0.2655 2.14e-33 7ebp:B, 7ebq:A
6 7pth:A 517 463 0.2622 0.2398 0.2678 3.90e-33 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
7 7sno:A 506 485 0.2706 0.2530 0.2639 1.21e-30
8 7stt:A 445 479 0.2770 0.2944 0.2735 1.43e-29 7stu:A, 7stv:A
9 8di0:B 426 371 0.2178 0.2418 0.2776 1.12e-28
10 6hr5:A 376 459 0.2664 0.3351 0.2745 9.59e-27
11 2w8s:B 513 513 0.2664 0.2456 0.2456 2.55e-26 2w8s:A, 2w8s:C, 2w8s:D
12 6s21:A 486 479 0.2537 0.2469 0.2505 4.33e-26 6s21:B, 6s21:C
13 6hhm:A 459 488 0.2579 0.2658 0.2500 6.81e-25
14 4upl:A 555 502 0.2748 0.2342 0.2590 1.01e-24 4upl:C
15 4upi:A 548 425 0.2431 0.2099 0.2706 1.44e-24
16 2vqr:A 512 540 0.2770 0.2559 0.2426 4.01e-24
17 7all:AAA 498 524 0.2685 0.2550 0.2424 8.44e-24
18 6j66:B 476 481 0.2622 0.2605 0.2578 3.33e-22 6j66:A
19 8eg3:A 554 449 0.2304 0.1968 0.2428 6.07e-22 1p49:A
20 5fql:A 507 351 0.1818 0.1696 0.2450 3.16e-21 6ioz:A
21 4cys:A 534 520 0.2579 0.2285 0.2346 4.00e-21 5aj9:A, 5aj9:B, 4cxk:A, 4cxk:B, 4cxs:A, 4cxs:B, 4cxu:A, 4cxu:B, 4cyr:A, 4cyr:B, 4cys:B, 1hdh:A, 1hdh:B
22 3b5q:B 467 475 0.2410 0.2441 0.2400 5.52e-21 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
23 6psm:C 448 474 0.2727 0.2879 0.2722 3.74e-20 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
24 6b0j:A 452 474 0.2410 0.2522 0.2405 1.58e-19 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
25 6ust:C 464 491 0.2558 0.2608 0.2464 1.67e-18 6ust:A, 6ust:B, 6ust:D
26 7ana:AAA 475 479 0.2474 0.2463 0.2443 2.52e-18 7ana:BBB, 7anb:AAA, 7anb:BBB
27 1fsu:A 475 377 0.2030 0.2021 0.2546 4.07e-18
28 5g2v:A 494 189 0.1247 0.1194 0.3122 4.33e-17
29 5g2v:A 494 109 0.0803 0.0769 0.3486 9.17e-16
30 7p24:AAA 494 202 0.1332 0.1275 0.3119 3.31e-16
31 7p24:AAA 494 241 0.1226 0.1174 0.2407 5.45e-09
32 1n2l:A 483 437 0.2347 0.2298 0.2540 3.80e-15 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
33 7an1:AAA 483 389 0.1924 0.1884 0.2339 1.62e-14 7oqd:AAA
34 4miv:A 484 414 0.2135 0.2087 0.2440 1.72e-12 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
35 7aj0:A 501 246 0.1543 0.1457 0.2967 3.20e-12 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
36 4fdi:A 494 405 0.1987 0.1903 0.2321 1.12e-11 4fdi:B, 4fdj:A, 4fdj:B
37 7ozc:AAA 485 109 0.0825 0.0804 0.3578 8.93e-11
38 7ozc:AAA 485 37 0.0338 0.0330 0.4324 2.1
39 6s20:C 480 130 0.0973 0.0958 0.3538 2.02e-10
40 6s20:C 480 214 0.1099 0.1083 0.2430 6.49e-04
41 9fvt:A 519 481 0.2368 0.2158 0.2328 2.35e-10 9fvt:B, 9fvt:C, 9fvt:D
42 7p26:AAA 484 113 0.0825 0.0806 0.3451 3.49e-10
43 7p26:AAA 484 210 0.1057 0.1033 0.2381 0.58
44 7oza:CCC 488 530 0.2600 0.2520 0.2321 1.61e-09 7oza:AAA
45 7oze:AAA 487 111 0.0782 0.0760 0.3333 1.99e-08 7oze:EEE, 7oze:FFF, 7oze:GGG
46 7oze:AAA 487 233 0.1205 0.1170 0.2446 0.027 7oze:EEE, 7oze:FFF, 7oze:GGG
47 6uss:A 485 491 0.2220 0.2165 0.2138 1.65e-07 6uss:B
48 2w8d:B 421 98 0.0507 0.0570 0.2449 3.77e-04 2w8d:A
49 7oz9:BBB 483 136 0.0698 0.0683 0.2426 0.002 7oz9:AAA
50 2w5q:A 424 86 0.0571 0.0637 0.3140 0.003 2w5r:A, 2w5s:A, 2w5t:A
51 3zfj:A 119 81 0.0465 0.1849 0.2716 0.066
52 4tn0:A 308 74 0.0444 0.0682 0.2838 0.090 4tn0:B, 4tn0:C
53 5tcd:A 388 120 0.0655 0.0799 0.2583 0.15 5udy:A
54 6km9:B 845 66 0.0444 0.0249 0.3182 0.27 6km9:A, 6kma:A, 6kma:B, 6kma:C, 6kma:D
55 4uop:B 409 102 0.0486 0.0562 0.2255 0.29 4uop:A
56 6c01:A 819 34 0.0275 0.0159 0.3824 0.30 6c01:B, 6c02:A, 6c02:B
57 4uor:A 418 76 0.0402 0.0455 0.2500 0.72 4uoo:A, 4uoo:B, 4uoo:C, 4uoo:D, 4uoo:E, 4uor:B, 4uor:C, 4uor:D, 4uor:E, 4uor:F, 4uor:G, 4uor:H, 4uor:I, 4uor:J, 4uor:K
58 7tl7:A 531 65 0.0381 0.0339 0.2769 1.8 5kgl:A, 5kgl:B, 5kgm:A, 5kgm:B, 5kgn:A, 5kgn:B, 7knf:A, 7knf:B, 7kng:A, 7kng:B, 7tl7:B, 7tl7:C, 7tl7:D
59 2evx:A 382 101 0.0550 0.0681 0.2574 2.0
60 6zj3:SE 265 66 0.0359 0.0642 0.2576 3.2
61 8p5s:A 1087 68 0.0444 0.0193 0.3088 4.1 8p5x:A, 8p5x:B, 8p5x:C, 8p5x:D, 8p5x:E, 8p5x:F
62 5vpu:A 509 110 0.0507 0.0472 0.2182 4.7
63 8p5v:A 1121 68 0.0444 0.0187 0.3088 4.9 8p5t:A, 8p5t:B, 8p5t:C, 8p5t:D, 8p5t:E, 8p5t:F, 8p5u:A, 8p5u:B, 8p5u:C, 8p5u:D, 8p5u:E, 8p5u:F, 8p5v:B, 8p5v:E, 8p5v:D, 8p5v:C, 8p5v:F, 8p5w:A, 8p5w:B, 8p5w:C, 8p5w:D, 8p5w:E, 8p5w:F
64 3way:A 787 30 0.0254 0.0152 0.4000 7.2 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
65 6wev:AbA 817 43 0.0317 0.0184 0.3488 7.2 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
66 8p5r:C 1109 67 0.0423 0.0180 0.2985 7.3 6i2q:A, 6i2r:A, 6i2r:C, 6i2s:A, 8p5r:A, 8p5r:B, 8p5r:D, 8p5r:E, 8p5r:F, 6r2b:A, 6r2b:D, 6r2c:A, 6r2c:B, 6r2c:C, 6r2c:D, 6r2d:A, 6r2d:B, 6r2d:C, 6r2d:D, 2xt6:A, 2xt6:B, 2xta:A, 2xta:B, 2xta:C, 2xta:D, 2y0p:D, 2yic:A, 2yic:B, 2yic:C, 2yic:D, 2yid:A, 2yid:B, 2yid:C, 2yid:D, 3zhq:A, 3zhq:B, 3zhq:C, 3zhq:D, 3zhr:A, 3zhr:B, 3zhr:C, 3zhr:D, 3zhs:A, 3zhs:B, 3zhs:C, 3zhs:D, 3zht:A, 3zht:B, 3zht:C, 3zht:D, 3zhu:A, 3zhu:B, 3zhu:C, 3zhu:D, 3zhv:A, 3zhv:B, 3zhv:C, 3zhv:D
67 6g4g:C 742 34 0.0233 0.0148 0.3235 7.7
68 4lqy:A 379 30 0.0233 0.0290 0.3667 7.7 4lr2:A
69 6f2t:B 722 34 0.0233 0.0152 0.3235 7.8 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
70 6g4g:B 759 34 0.0233 0.0145 0.3235 8.1
71 6g4g:D 781 34 0.0233 0.0141 0.3235 8.1 6g4g:A
72 2y0p:C 856 67 0.0423 0.0234 0.2985 8.1 6r29:A, 6r29:B, 6r2a:A, 6r2a:B, 6r2b:B, 6r2b:C, 2y0p:A, 2y0p:B
73 5s9m:A 809 30 0.0254 0.0148 0.4000 8.8 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
74 2xrg:A 758 30 0.0254 0.0158 0.4000 8.9
75 4zg9:B 764 30 0.0254 0.0157 0.4000 9.3 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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