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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAGEIDL
YIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYRE
QTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL

The query sequence (length=220) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4m8l:A 220 220 1.0000 1.0000 1.0000 6.67e-160 3kwm:D, 4m8l:B, 4m8l:D, 4m8l:C
2 3env:A 217 211 0.5636 0.5714 0.5877 2.22e-83 3enw:A, 3enw:B
3 1o8b:B 212 211 0.5273 0.5472 0.5498 9.03e-75 1o8b:A
4 6mc0:A 218 210 0.5182 0.5229 0.5429 1.37e-73 6mc0:B
5 3uw1:A 232 219 0.4682 0.4440 0.4703 1.77e-64
6 4gmk:A 227 220 0.3955 0.3833 0.3955 1.41e-40 4gmk:B
7 1lk7:A 229 222 0.4182 0.4017 0.4144 4.13e-40 1lk7:B, 1lk7:C, 1lk7:D
8 1uj5:A 225 213 0.3864 0.3778 0.3991 6.16e-33 1uj6:A
9 3hhe:A 233 230 0.4045 0.3820 0.3870 4.65e-32 3hhe:B
10 2f8m:A 237 236 0.3545 0.3291 0.3305 2.80e-23 2f8m:B
11 8asw:A 1255 63 0.0955 0.0167 0.3333 1.3
12 6v1s:E 276 52 0.0818 0.0652 0.3462 1.4 6v1s:A, 6v1s:B, 6v1s:C, 6v1s:D, 6v1s:F, 6v1s:G
13 8ekk:A 533 52 0.0818 0.0338 0.3462 1.6 8ekk:B, 8ekk:C, 8ekk:D, 8ekk:E, 8ekk:F, 8ekk:G, 8ekl:A, 8ekl:B, 8ekl:C, 8ekl:D, 8ekl:E, 8ekl:F, 8ekl:G
14 8dcm:C 695 52 0.0818 0.0259 0.3462 1.8
15 7vnn:D 641 52 0.0818 0.0281 0.3462 1.9 8ekm:A, 8ekm:B, 8ekm:C, 8ekm:D, 8ekm:E, 8ekm:F, 8ekm:G, 7vnj:A, 7vnj:B, 7vnj:C, 7vnj:D, 7vnj:E, 7vnj:F, 7vnj:G, 7vnn:A, 7vnn:B, 7vnn:C, 7vnn:E, 7vnn:F, 7vnn:G, 7yvq:A, 7yvq:B, 7yvq:C, 7yvq:D, 7yvq:E, 7yvq:F, 7yvq:G, 7yvs:A, 7yvs:B, 7yvs:C, 7yvs:D, 7yvs:E, 7yvs:F, 7yvs:G
16 6uwr:A 660 52 0.0818 0.0273 0.3462 1.9 6uwi:A, 6uwi:h, 6uwi:G, 6uwi:n, 6uwi:F, 6uwi:m, 6uwi:E, 6uwi:l, 6uwi:D, 6uwi:k, 6uwi:C, 6uwi:j, 6uwi:B, 6uwi:i, 6uwi:H, 6uwi:a, 6uwi:I, 6uwi:b, 6uwi:J, 6uwi:c, 6uwi:K, 6uwi:d, 6uwi:L, 6uwi:e, 6uwi:M, 6uwi:f, 6uwi:N, 6uwi:g, 6uwr:B, 6uwr:C, 6uwr:D, 6uwr:E, 6uwr:F, 6uwr:G, 6uwr:H, 6uwr:I, 6uwr:J, 6uwr:K, 6uwr:L, 6uwr:M, 6uwr:N, 6uwt:H, 6uwt:I, 6uwt:J, 6uwt:K, 6uwt:L, 6uwt:M, 6uwt:N, 6uwt:A, 6uwt:B, 6uwt:C, 6uwt:D, 6uwt:E, 6uwt:F, 6uwt:G
17 7nqf:B 219 40 0.0727 0.0731 0.4000 2.3 7nqe:A, 7nqf:A, 7p9j:B, 7p9j:A, 7p9j:C, 7qaz:B, 7qaz:A, 7qaz:C
18 2y9z:B 595 39 0.0636 0.0235 0.3590 2.6
19 6klo:A 368 54 0.0864 0.0516 0.3519 3.2 6klo:B, 6klo:C, 6klo:D, 6klo:E, 6klo:F, 6klo:G, 6klx:A, 6klx:B, 6klx:C, 6klx:D, 6klx:E, 6klx:F, 6klx:G
20 6klw:A 406 54 0.0864 0.0468 0.3519 4.0 6klw:B, 6klw:C, 6klw:D, 6klw:E, 6klw:F, 6klw:G
21 2xze:A 141 34 0.0500 0.0780 0.3235 5.5 2xze:B
22 8adb:A 209 81 0.1045 0.1100 0.2840 5.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218