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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKLWQKGGGWLLEVPERVYTPEDFDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPEEYG
GLDLPKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAYCLTEPGSGSDALAAKTRA
TLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVDGEHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVEN
VLGEIGKGHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESAVYRTV
GLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYSQEYPIERAYRDARINRIFEGTNEIN
RLLIPGMLLRREDLELHQVQNLKKLALMVAGLAVQKYGQGVEEEQEVLGAVADILIDAYAAESALLRARRLGGLAPVLAR
IYLAQALDRAQAGALSVLPRLVEGDEARVVYSAARRLTKREPGDLVALRRQAAEAVLEAGGYPIPR

The query sequence (length=546) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2z1q:B 549 549 1.0000 0.9945 0.9945 0.0 2z1q:A
2 3owa:C 587 585 0.5751 0.5349 0.5368 0.0 3owa:A, 3owa:B, 3owa:D
3 8phe:A 551 435 0.3553 0.3521 0.4460 5.62e-112 8phe:B, 8phf:A, 8phf:B
4 7s7g:A 571 452 0.3370 0.3222 0.4071 3.79e-92 3b96:A, 2uxw:A
5 5lnx:D 374 382 0.3040 0.4439 0.4346 4.52e-89 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
6 5ol2:F 378 379 0.2894 0.4180 0.4169 7.60e-88 5ol2:C
7 8ca1:B 589 464 0.3370 0.3124 0.3966 3.67e-87 8ca1:A
8 1ukw:A 379 393 0.2949 0.4248 0.4097 5.34e-84 1ukw:B
9 7y0a:C 387 398 0.2802 0.3953 0.3844 1.63e-83 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
10 4n5f:A 378 391 0.2802 0.4048 0.3913 7.47e-79 4n5f:B
11 4l1f:A 380 395 0.2875 0.4132 0.3975 4.40e-78 4l1f:B
12 2a1t:C 388 390 0.2637 0.3711 0.3692 1.30e-76 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
13 1buc:A 383 390 0.2821 0.4021 0.3949 1.85e-76 1buc:B
14 3mdd:A 385 390 0.2619 0.3714 0.3667 3.76e-75 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
15 7w0j:E 382 341 0.2418 0.3455 0.3871 1.30e-72 8i4p:A, 8i4r:A, 7w0j:B, 7w0j:C, 7w0j:H
16 3pfd:C 369 379 0.2546 0.3767 0.3668 3.21e-72 3pfd:A, 3pfd:B, 3pfd:D
17 6fah:D 379 395 0.2637 0.3799 0.3646 3.57e-72 6fah:C
18 2dvl:A 370 373 0.2802 0.4135 0.4102 4.31e-72 2dvl:B
19 4m9a:B 376 391 0.2766 0.4016 0.3862 1.69e-71 4m9a:A
20 1rx0:A 384 390 0.2436 0.3464 0.3410 5.23e-71 1rx0:C, 1rx0:B, 1rx0:D
21 2jif:A 381 392 0.2564 0.3675 0.3571 8.68e-68 2jif:C, 2jif:B, 2jif:D
22 8sgr:A 393 389 0.2454 0.3410 0.3445 1.79e-66 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
23 2pg0:A 380 379 0.2546 0.3658 0.3668 2.31e-65 2pg0:B
24 4iv6:B 383 398 0.2601 0.3708 0.3568 2.82e-63 4iv6:A
25 7szv:A 372 386 0.2436 0.3575 0.3446 9.85e-63 7szv:B
26 3nf4:A 369 382 0.2436 0.3604 0.3482 4.21e-62 3nf4:B
27 4irn:A 378 382 0.2527 0.3651 0.3613 4.73e-62 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
28 3mpi:C 395 395 0.2399 0.3316 0.3316 6.48e-61 3mpi:A, 3mpi:B, 3mpi:D, 3mpj:B, 3mpj:A, 3mpj:D, 3mpj:E, 3mpj:F, 3mpj:G
29 4kto:A 377 381 0.2546 0.3687 0.3648 2.10e-60 4kto:C, 4kto:B, 4kto:D
30 2d29:A 386 398 0.2894 0.4093 0.3970 2.20e-60 2d29:B
31 7p9a:A 380 348 0.2125 0.3053 0.3333 4.98e-56 7p98:A, 7p98:B, 7p9a:B, 7p9x:A, 7p9x:B, 7p9x:C, 7p9x:D
32 8w0t:A 398 396 0.2289 0.3141 0.3157 6.53e-53 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
33 6es9:A 545 402 0.2436 0.2440 0.3308 4.55e-51 6es9:B
34 3r7k:A 378 396 0.2381 0.3439 0.3283 1.11e-50 3r7k:B, 3r7k:C, 3r7k:D
35 2r0m:A 390 377 0.2253 0.3154 0.3263 2.85e-50 2r0n:A, 1siq:A, 1sir:A
36 3gqt:C 385 272 0.1886 0.2675 0.3787 3.70e-50 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
37 5idu:C 405 375 0.2326 0.3136 0.3387 1.86e-49 5idu:A, 5idu:B, 5idu:D
38 3sf6:A 387 382 0.2418 0.3411 0.3455 6.29e-46
39 5jsc:A 388 322 0.2033 0.2861 0.3447 1.25e-45 5jsc:B, 5jsc:C, 5jsc:D
40 2eba:A 380 392 0.2234 0.3211 0.3112 3.66e-44 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
41 3oib:A 381 372 0.2308 0.3307 0.3387 7.17e-44 3oib:B, 3p4t:A, 3p4t:B
42 6af6:A 383 356 0.2033 0.2898 0.3118 1.16e-42 5zw2:A, 5zw7:A, 5zw8:A
43 7xp7:B 376 367 0.2271 0.3298 0.3379 1.36e-41 7xp7:A, 7xp7:C, 7xp7:D
44 3swo:A 388 287 0.1740 0.2448 0.3310 3.92e-41 3swo:D, 3swo:B, 3swo:C
45 6cxt:B 372 353 0.1795 0.2634 0.2776 1.29e-39 6cy8:B
46 2ix6:A 416 387 0.2070 0.2716 0.2920 5.67e-37 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
47 8ciw:A 555 422 0.2234 0.2198 0.2891 4.40e-33 8ciw:B
48 5af7:B 391 376 0.1978 0.2762 0.2872 1.12e-32 5af7:A, 5ahs:A, 5ahs:B, 5ahs:C, 5ahs:E, 5ahs:F, 5ahs:D
49 6u1v:B 389 376 0.1832 0.2571 0.2660 5.36e-29 6u1v:A, 6u1v:C, 6u1v:D
50 4hr3:A 407 403 0.2033 0.2727 0.2754 4.33e-26
51 2wbi:B 398 307 0.1593 0.2186 0.2834 6.56e-26 2wbi:A
52 6kse:A 607 379 0.1996 0.1796 0.2876 1.68e-22 6kse:B
53 4x28:A 386 409 0.2015 0.2850 0.2689 3.08e-21 4x28:B
54 6ksa:B 611 379 0.1886 0.1686 0.2718 1.21e-20 6kpt:A, 6kpt:B, 6kri:A, 6kri:B, 6ks9:A, 6ks9:B, 6ksa:A, 6ksb:A, 6ksb:B, 6lpy:A, 6lpy:B, 6lq0:A, 6lq0:B, 6lq1:A, 6lq1:B, 6lq2:A, 6lq2:B, 6lq3:A, 6lq3:B, 6lq4:A, 6lq4:B, 6lq5:A, 6lq5:B, 6lq6:A, 6lq6:B, 6lq7:A, 6lq7:B, 6lq8:A, 6lq8:B
55 1r2j:A 353 363 0.1813 0.2805 0.2727 1.38e-20
56 6wy8:B 384 237 0.1355 0.1927 0.3122 1.75e-19 6wy8:D, 6wy9:A
57 8hk0:B 379 208 0.1227 0.1768 0.3221 1.04e-16 8hk0:A
58 6wy8:C 364 358 0.1813 0.2720 0.2765 4.94e-16 6wy8:A, 6wy9:B
59 6sd8:X 503 323 0.1484 0.1610 0.2508 1.31e-15 6sd8:A, 6sda:A, 6sda:B
60 5ys9:A 692 349 0.1557 0.1228 0.2436 4.20e-15 5ys9:B
61 3u33:A 540 261 0.1209 0.1222 0.2529 1.78e-14 3djl:A, 3u33:B, 3u33:C, 3u33:D, 3u33:E, 3u33:F, 3u33:G, 3u33:H, 3u33:I, 3u33:J, 3u33:K, 3u33:L
62 4y9j:B 593 407 0.1758 0.1619 0.2359 7.80e-14 4y9j:A, 4y9l:A, 4y9l:B
63 5z8t:A 395 336 0.1575 0.2177 0.2560 3.40e-13 5z8t:B, 5z8t:C
64 5ez3:B 541 272 0.1264 0.1275 0.2537 3.57e-13 5ez3:A, 5ez3:C, 5ez3:D
65 5y9d:A 687 327 0.1502 0.1194 0.2508 1.10e-11 5y9d:B
66 3x0y:A 402 183 0.0989 0.1343 0.2951 2.63e-11 3x0y:F, 3x0y:C, 3x0y:E, 3x0y:B, 3x0y:D
67 4zyj:D 392 363 0.1777 0.2474 0.2672 1.62e-10 4zyj:A, 4zyj:B, 4zyj:C
68 4x28:D 364 393 0.1813 0.2720 0.2519 7.14e-09 4x28:C
69 4kcf:A 407 338 0.1429 0.1916 0.2308 4.20e-08 3m9v:A
70 3d9d:A 432 371 0.1557 0.1968 0.2291 2.05e-07 2c0u:A, 2c0u:B, 2c0u:C, 2c0u:D, 2c12:A, 2c12:B, 2c12:C, 2c12:D, 2c12:E, 2c12:F, 3d9d:B, 3d9d:C, 3d9d:D, 3d9e:A, 3d9e:B, 3d9e:C, 3d9e:D, 3d9f:A, 3d9f:B, 3d9f:C, 3d9f:D, 3d9g:A, 3d9g:B, 3d9g:C, 3d9g:D, 3fcj:A, 3fcj:B, 3fcj:C, 3fcj:D, 2reh:A, 2reh:B, 2reh:C, 2reh:D, 2zaf:A, 2zaf:B, 2zaf:C, 2zaf:D
71 7q86:A 612 347 0.1538 0.1373 0.2421 4.64e-06 7q86:B
72 3mkh:A 426 382 0.1703 0.2183 0.2435 9.06e-06 3mkh:B, 3mkh:C, 3mkh:D
73 1w07:B 658 201 0.0861 0.0714 0.2338 1.01e-04 1w07:A
74 1is2:A 637 457 0.1758 0.1507 0.2101 1.69e-04 2ddh:A, 1is2:B
75 4xvx:B 373 319 0.1300 0.1903 0.2226 6.92e-04 4xvx:A
76 2fon:B 656 205 0.0861 0.0716 0.2293 8.25e-04 2fon:A, 2fon:C
77 5k3i:A 661 293 0.1190 0.0983 0.2218 0.002 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
78 2rfq:A 388 211 0.0842 0.1186 0.2180 0.062 2rfq:B, 2rfq:C, 2rfq:D
79 5k3j:A 662 156 0.0678 0.0559 0.2372 0.27 5k3j:B
80 5mr6:A 396 191 0.0806 0.1111 0.2304 0.45 5lvw:A, 5mr6:D, 5mr6:B, 5mr6:C, 5mr6:E, 5mr6:H, 5mr6:F, 5mr6:G, 5mr6:I, 5mr6:L, 5mr6:J, 5mr6:K, 5mr6:M, 5mr6:P, 5mr6:N, 5mr6:O, 5mr6:Q, 5mr6:R, 5mr6:S, 5mr6:T, 5mr6:U, 5mr6:V, 5mr6:W, 5mr6:X
81 6tfo:C 424 82 0.0476 0.0613 0.3171 1.7 6tfd:A, 6tfd:C, 6tfd:B, 6tfo:A, 6tfo:B
82 6ks6:b 518 35 0.0256 0.0270 0.4000 8.3 6ks6:B, 4v81:B, 4v81:J, 4v81:b, 4v8r:AB, 4v8r:Ab, 4v8r:BB, 4v8r:Bb, 4v94:B, 4v94:J, 4v94:b, 4v94:j, 7ylw:B, 7ylw:b, 7ylx:B, 7ylx:b, 7yly:B, 7yly:b

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218