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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGV
DRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEAT
LSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINI
ATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLY
VAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCD
ICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAA
LSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVF
AIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFIT
NVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKD
RKEAELALLLYIYEIRK

The query sequence (length=737) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ifu:A 706 737 0.9552 0.9972 0.9552 0.0
2 6nud:J 741 744 0.9457 0.9406 0.9368 0.0 6ifk:A, 6ifn:A, 6ify:A, 6ifz:A, 6ig0:A, 6nue:J
3 6ifr:A 694 737 0.9403 0.9986 0.9403 0.0 6ifl:A
4 8wfx:A 801 806 0.4342 0.3995 0.3970 0.0
5 9ash:A 753 779 0.4179 0.4090 0.3954 1.59e-163 9asi:A, 6xn3:A, 6xn4:A, 6xn5:A, 6xn7:A
6 7v00:F 695 756 0.3650 0.3871 0.3558 1.06e-136 7v01:F
7 7v02:F 650 740 0.3460 0.3923 0.3446 1.91e-129
8 6kc0:A 674 764 0.3134 0.3427 0.3024 3.36e-92 6kbd:A
9 6muu:A 780 731 0.2578 0.2436 0.2599 2.50e-56 6iqw:A, 6mur:A, 6mus:A, 6mut:A, 6o7e:A, 6o7h:A
10 6o7i:A 741 761 0.2700 0.2686 0.2615 1.84e-54
11 6o75:A 710 705 0.2415 0.2507 0.2525 5.57e-47 6o74:A, 6o78:A, 6o79:A, 6o7b:A, 6o7d:A
12 4doz:A 557 252 0.0787 0.1041 0.2302 4.35e-05 3ung:C, 3ur3:C
13 3w2w:A 618 217 0.0733 0.0874 0.2488 6.05e-04 4h4k:C, 3w2v:A
14 4w8y:A 835 157 0.0543 0.0479 0.2548 0.020 4w8y:B
15 3x1l:A 573 152 0.0543 0.0698 0.2632 0.18
16 3csl:A 753 182 0.0570 0.0558 0.2308 0.36 3csl:B, 3ddr:A, 3ddr:B
17 1i9z:A 336 77 0.0285 0.0625 0.2727 2.3
18 2nx9:B 453 126 0.0407 0.0662 0.2381 2.9 2nx9:A
19 6zhp:B 341 36 0.0204 0.0440 0.4167 5.4 7fdy:A, 7fdy:B, 7fdy:C, 7ff7:A, 7ff7:B, 7ff7:C, 3fyx:A, 4gcp:A, 4gcp:B, 4gcq:A, 4gcq:B, 4gcs:A, 1gfm:A, 1gfn:A, 1gfo:A, 1gfp:A, 1gfq:A, 4lse:A, 4lse:B, 4lse:C, 4lsi:A, 4lsi:B, 4lsi:C, 1mpf:A, 5nuo:C, 5nuo:A, 5nuo:E, 5nuq:A, 5nuq:B, 5nuq:D, 5nuq:F, 5nur:E, 5nur:C, 5nur:A, 3o0e:A, 3o0e:F, 3o0e:C, 3o0e:D, 3o0e:E, 3o0e:B, 2omf:A, 2zfg:A, 6zhv:B, 6zhv:A, 6zhv:C, 2zld:A, 2zld:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218