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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRV
EEFKLKQMWKSPNGTIRNILGGTVFREAIICKNPIIIGHHATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVGFIWA
CKNLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSI
ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ

The query sequence (length=367) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4i3k:A 367 367 1.0000 1.0000 1.0000 0.0 4i3k:B, 4i3l:A, 4i3l:B
2 3mar:A 393 388 1.0000 0.9338 0.9459 0.0 5sun:A, 5sun:B, 8t7d:B, 8t7d:C, 8t7d:D, 4umy:A, 4umy:B, 4xrx:A, 4xrx:B, 4xs3:A, 4xs3:B
3 8vhe:B 421 408 0.9973 0.8694 0.8971 0.0 6adg:A, 6adg:B, 6b0z:A, 6b0z:C, 6b0z:B, 6b0z:D, 8bay:A, 8bay:B, 8bay:C, 6bkx:C, 6bkx:B, 6bkx:A, 6bky:D, 6bky:C, 6bky:E, 6bky:A, 6bky:B, 6bky:F, 6bkz:A, 6bkz:B, 6bl0:A, 6bl0:B, 6bl0:C, 6bl1:B, 6bl1:A, 6bl1:C, 6bl2:C, 6bl2:A, 6bl2:B, 5de1:A, 5de1:B, 8hb9:AAA, 8hb9:BBB, 8hb9:CCC, 8hb9:DDD, 3inm:A, 3inm:B, 3inm:C, 6io0:A, 6io0:B, 5k10:A, 5k10:B, 5k11:A, 5k11:B, 8kib:A, 8kib:B, 8kib:C, 8kib:D, 4kzo:A, 4kzo:B, 4kzo:C, 4l03:A, 4l03:B, 4l03:C, 4l04:A, 4l04:B, 4l04:C, 4l04:D, 4l04:E, 4l04:F, 4l06:A, 4l06:B, 4l06:C, 4l06:D, 4l06:E, 4l06:F, 5l57:A, 5lge:A, 5lge:B, 5lge:C, 5lge:D, 3map:A, 3map:B, 3mar:B, 3mas:A, 3mas:B, 6o2y:A, 6o2y:B, 6o2y:C, 6o2z:A, 6o2z:B, 6pay:A, 6pay:D, 6pay:C, 7pjm:A, 7pjm:B, 7pjm:C, 7pjn:A, 7pjn:B, 7pjn:C, 7pjn:D, 6q6f:A, 6q6f:B, 5svf:A, 5svf:C, 5svf:B, 5svf:D, 1t09:A, 1t09:B, 1t0l:A, 1t0l:B, 1t0l:C, 1t0l:D, 8t7d:A, 8t7n:A, 8t7n:B, 8t7o:A, 8t7o:B, 5tqh:A, 5tqh:B, 5tqh:C, 5tqh:D, 6u4j:A, 6u4j:B, 4umx:A, 4umx:B, 6vei:A, 6vei:B, 6vg0:A, 6vg0:B, 6vg0:C, 8vh9:A, 8vh9:B, 8vha:A, 8vha:B, 8vha:C, 8vha:D, 8vhb:A, 8vhb:B, 8vhb:C, 8vhb:D, 8vhc:A, 8vhc:B, 8vhd:A, 8vhd:B, 8vhd:C, 8vhd:D, 8vhe:A, 8vhe:C, 8vhe:D, 8w49:A, 8w49:B, 8w49:C, 8w49:D, 5yfm:A, 5yfm:B, 5yfm:C, 5yfn:A, 5yzh:A, 5yzh:B, 5yzi:A, 5yzi:B
4 6adg:C 390 408 0.9428 0.8872 0.8480 0.0
5 5l58:A 376 396 0.9210 0.8989 0.8535 0.0
6 6ajc:A 413 400 0.6785 0.6029 0.6225 5.83e-179 6ajc:B, 6ajc:C, 6ajc:D, 6ajc:E, 6ajc:F, 6ajc:G, 6ajc:H
7 6adi:A 418 403 0.6785 0.5957 0.6179 4.63e-175 6adi:B, 5h3e:B, 5h3f:A, 5h3f:B, 5i95:A, 5i96:A, 5i96:B, 4ja8:A, 4ja8:B, 5svn:A, 5svn:B, 5svo:A, 5svo:B, 6vfz:A, 6vfz:B
8 6aj6:A 413 409 0.6594 0.5860 0.5917 3.06e-169 6aj6:C, 6aj8:A, 6aj8:B, 6aja:A, 6aja:B, 6aja:C, 6aja:D, 6ajb:A, 6ajb:B, 6ajb:C, 6ajb:D, 7e3n:A
9 4hcx:A 402 399 0.6267 0.5721 0.5764 6.78e-159 4hcx:B
10 2qfy:A 411 401 0.6458 0.5766 0.5910 2.70e-158 2qfv:A, 2qfv:B, 2qfv:C, 2qfv:D, 2qfx:A, 2qfx:B, 2qfx:C, 2qfx:D, 2qfx:E, 2qfx:F, 2qfy:B, 2qfy:C, 2qfy:D, 2qfy:E, 2qfy:F
11 4aou:A 401 392 0.5586 0.5112 0.5230 1.38e-127
12 2uxq:A 402 398 0.4850 0.4428 0.4472 7.51e-107 4aov:A, 2uxr:B
13 6ixn:A 405 414 0.3106 0.2815 0.2754 9.37e-30 7e2w:A, 6ixn:B, 6ixn:C, 6ixn:D, 6ixt:A, 6ixt:C
14 7olc:Sa 104 43 0.0409 0.1442 0.3488 0.58 7old:Sa, 8oo0:Sa, 7r81:b2, 7z3n:Sa, 7z3o:Sa
15 3blv:C 344 185 0.1281 0.1366 0.2541 2.5 3blv:A, 3blv:E, 3blv:G, 3blw:A, 3blw:C, 3blw:E, 3blw:G, 3blw:I, 3blw:K, 3blw:M, 3blw:O
16 4ccz:A 611 77 0.0736 0.0442 0.3506 4.6
17 8ity:B 1105 96 0.0654 0.0217 0.2500 5.5 7a6h:B, 7ae1:B, 7ae3:B, 7aea:B, 7d58:B, 7d59:B, 7fji:B, 7fjj:B, 8iue:B, 8iuh:B
18 6wxp:F 144 58 0.0518 0.1319 0.3276 6.2
19 5cc2:A 256 29 0.0272 0.0391 0.3448 7.8 2v3t:A, 2v3t:B, 2v3u:A
20 6xwb:A 319 97 0.0654 0.0752 0.2474 8.8 6xwb:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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