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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KHRIEPVCLIIRGSPGTGKSLATGIIARAIADKYHSSVYSLPPDPDHFDGYKQQVVTVMDDLCQNPDGKDMSLFCQMVST
VDFIPPMASLAEAGVSFTSKFVIASTNATNIISDSDAIRRRFYMDCDIEVTDSYKTDLGRLDAGRAAKLCSENNTANFKR
CSPLVCGKAIQLRDRKSKVRYSVDTVVSELIREYSNRSAIGNTIEALF

The query sequence (length=208) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5grb:B 212 212 1.0000 0.9811 0.9811 1.60e-153 5gq1:A, 5gq1:B, 5gq1:C, 5gq1:D, 5grb:A, 5grb:C, 5grb:D, 5grb:E, 5grb:F
2 5gq1:F 173 207 0.8317 1.0000 0.8357 1.40e-113
3 5z3q:B 204 209 0.6346 0.6471 0.6316 2.94e-94 5z3q:A, 5z3q:D, 5z3q:C, 5z3q:E
4 6s3a:A 209 213 0.6058 0.6029 0.5915 7.09e-89 6t3w:A
5 8x3v:B 209 212 0.3654 0.3636 0.3585 6.64e-35 8x3v:A
6 7lar:D 183 102 0.1346 0.1530 0.2745 0.016 7lar:E, 7lar:A, 7lar:B, 7lar:C, 7las:D, 7las:E, 7las:A, 7las:B, 7las:C
7 2r65:A 249 36 0.0625 0.0522 0.3611 0.81 2r65:B, 2r65:C, 2r65:D, 2r65:E
8 5vc7:A 544 36 0.0721 0.0276 0.4167 1.3 5vc7:C, 5vc7:D, 5vc7:E, 5vc7:F, 5vc7:G
9 8bx8:C 3947 76 0.1058 0.0056 0.2895 1.6 7k58:C, 7k5b:C, 7kek:C
10 7udu:D 701 24 0.0577 0.0171 0.5000 1.9 7rb8:D
11 5t5q:C 245 103 0.1298 0.1102 0.2621 2.5 5t5q:A, 5t5q:B, 5t5q:D
12 7otj:A 438 38 0.0721 0.0342 0.3947 2.9 7otj:B
13 8ah3:A 375 68 0.0962 0.0533 0.2941 3.5
14 1y63:A 168 42 0.0673 0.0833 0.3333 4.9
15 6oif:A 282 58 0.0913 0.0674 0.3276 5.2 5j1s:A, 5j1t:A, 6oif:C, 6oif:B, 6oif:E, 6oif:D, 6oif:G, 6oif:F, 6oif:I, 6oif:H, 6oif:K, 6oif:J, 6oif:M, 6oif:L, 6oif:O, 6oif:N, 6oif:Q, 6oif:P, 6oif:S, 6oif:R, 6oif:U, 6oif:T, 6oif:W, 6oif:V, 6oif:Y, 6oif:X
16 7e34:B 142 47 0.0673 0.0986 0.2979 6.0
17 7zbh:B 374 36 0.0625 0.0348 0.3611 6.3 7zbh:A, 7zbh:D, 7zbh:F, 7zbh:I, 7zbh:K
18 7mhs:E 489 28 0.0625 0.0266 0.4643 6.7
19 6fvt:J 405 32 0.0673 0.0346 0.4375 6.7 6ef0:J, 6ef1:J, 6ef2:J, 6ef3:J, 6fvu:J, 6fvv:J, 6fvw:J, 6fvx:J, 6fvy:J, 5mp9:J, 5mpa:J, 5mpb:J, 5mpc:J, 7qo4:J, 7qo5:J, 7qo6:J
20 4p5w:A 312 16 0.0481 0.0321 0.6250 6.8 4p5w:B
21 7vcs:A 766 28 0.0625 0.0170 0.4643 6.9 8b5r:A, 8b5r:B, 8b5r:C, 5b6c:A, 9boq:A, 9boq:B, 9boq:C, 9boq:D, 9boq:E, 9boq:F, 9boq:G, 9boq:H, 9boq:I, 9boq:J, 9boq:K, 9boq:L, 7bp8:A, 7bp8:B, 7bp8:C, 7bp8:D, 7bp8:E, 7bp8:F, 7bp9:A, 7bp9:B, 7bp9:C, 7bp9:D, 7bp9:E, 7bp9:F, 7bpa:A, 7bpa:F, 7bpa:B, 7bpa:C, 7bpa:D, 7bpa:E, 7bpb:A, 7bpb:F, 7bpb:B, 7bpb:C, 7bpb:D, 7bpb:E, 5c18:A, 5c18:B, 5c18:C, 5c18:D, 5c18:E, 5c18:F, 5c1a:A, 5c1a:B, 5c1a:C, 5c1a:D, 5c1a:E, 5c1a:F, 5c1a:G, 5c1a:H, 5c1a:I, 5c1a:J, 5c1a:K, 5c1a:L, 5c1b:D, 5c1b:A, 5c1b:B, 5c1b:C, 5c1b:E, 5c1b:F, 3cf1:A, 3cf1:B, 3cf1:C, 3cf2:A, 3cf2:B, 3cf2:C, 3cf2:D, 3cf3:A, 3cf3:B, 3cf3:C, 5dyg:A, 5dyi:A, 5dyi:B, 5dyi:C, 5dyi:D, 5dyi:E, 5dyi:F, 5dyi:G, 5dyi:H, 5dyi:I, 5dyi:J, 5dyi:K, 5dyi:L, 1e32:A, 5epp:A, 8fcl:A, 8fcl:B, 8fcl:C, 8fcl:D, 8fcl:E, 8fcl:F, 8fcm:B, 8fcm:E, 8fcm:D, 8fcm:C, 8fcm:A, 8fcm:F, 8fcn:F, 8fcn:E, 8fcn:D, 8fcn:C, 8fcn:B, 8fcn:A, 8fco:C, 8fco:B, 8fco:A, 8fco:F, 8fco:E, 8fco:D, 8fcp:E, 8fcp:D, 8fcp:C, 8fcp:B, 8fcp:A, 8fcp:F, 8fcq:B, 8fcq:A, 8fcq:F, 8fcq:E, 8fcq:D, 8fcq:C, 8fcr:A, 8fcr:B, 8fcr:C, 8fcr:D, 8fcr:E, 8fcr:F, 8fct:F, 8fct:A, 8fct:B, 8fct:C, 8fct:D, 8fct:E, 5ftj:A, 5ftj:B, 5ftj:C, 5ftj:D, 5ftj:E, 5ftj:F, 5ftk:A, 5ftk:B, 5ftk:C, 5ftk:D, 5ftk:E, 5ftk:F, 5ftl:A, 5ftl:B, 5ftl:C, 5ftl:D, 5ftl:E, 5ftl:F, 5ftm:A, 5ftm:F, 5ftm:B, 5ftm:C, 5ftm:D, 5ftm:E, 5ftn:A, 5ftn:B, 5ftn:C, 5ftn:D, 5ftn:E, 5ftn:F, 5glf:A, 5glf:C, 5glf:E, 5glf:G, 6hd0:B, 6hd0:T, 6hd0:U, 6hd0:V, 6hd0:A, 6hd0:C, 8hl7:B, 8hrz:A, 8hrz:B, 8hrz:C, 8hrz:D, 8hrz:E, 8hrz:F, 8hrz:G, 8hrz:H, 8hrz:I, 8hrz:J, 8hrz:K, 8hrz:L, 3hu1:A, 3hu1:B, 3hu1:C, 3hu1:D, 3hu1:E, 3hu1:F, 3hu2:A, 3hu2:B, 3hu2:C, 3hu2:D, 3hu2:E, 3hu2:F, 3hu3:A, 3hu3:B, 5ifs:B, 5ifs:D, 7jy5:A, 7jy5:F, 7jy5:B, 7jy5:C, 7jy5:D, 7jy5:E, 8kg2:A, 8kg2:B, 8kg2:C, 8kg2:D, 8kg2:E, 8kg2:F, 8kg2:G, 8kg2:H, 8kg2:I, 8kg2:J, 8kg2:K, 8kg2:L, 5kiw:A, 5kiw:B, 5kiy:A, 4kln:A, 4kln:B, 4kln:C, 4kln:D, 4kln:E, 4kln:F, 4ko8:A, 4ko8:B, 4kod:A, 4kod:B, 4kod:C, 4kod:D, 4kod:E, 4kod:F, 4kod:G, 4kod:H, 4kod:I, 4kod:J, 4kod:K, 4kod:L, 7lmy:A, 7lmy:B, 7lmy:C, 7lmy:D, 7lmy:E, 7lmy:F, 7lmz:B, 7lmz:C, 7lmz:D, 7lmz:E, 7lmz:A, 7ln0:B, 7ln0:C, 7ln0:D, 7ln0:E, 7ln0:A, 7ln1:B, 7ln1:C, 7ln1:D, 7ln1:E, 7ln1:A, 7ln2:A, 7ln2:B, 7ln2:C, 7ln2:D, 7ln2:E, 7ln3:A, 7ln3:B, 7ln3:C, 7ln3:D, 7ln3:E, 7ln4:A, 7ln4:B, 7ln4:C, 7ln4:D, 7ln4:E, 7ln5:A, 7ln5:B, 7ln5:C, 7ln5:D, 7ln5:E, 7ln6:A, 7ln6:B, 7ln6:C, 7ln6:D, 7ln6:E, 7mdm:B, 7mdm:C, 7mdm:D, 7mdm:E, 7mdm:A, 7mdm:F, 7mdo:A, 7mdo:B, 7mdo:C, 7mdo:D, 7mdo:E, 7mdo:F, 7mhs:A, 7mhs:B, 7mhs:C, 7mhs:D, 7oat:B, 8ooi:A, 8ooi:F, 8ooi:B, 8ooi:D, 8ooi:C, 8ooi:E, 8pqx:A, 8pqx:B, 8pqx:C, 8pqx:D, 8pqx:E, 8pqx:F, 7pux:A, 3qq7:A, 1r7r:A, 7r7s:A, 7r7s:B, 7r7s:C, 7r7s:D, 7r7s:E, 7r7s:F, 7r7t:A, 7r7t:B, 7r7t:F, 7r7t:E, 7r7t:D, 7r7t:C, 7rl6:A, 7rl6:B, 7rl6:C, 7rl6:D, 7rl6:E, 7rl6:F, 7rl7:A, 7rl7:B, 7rl7:C, 7rl7:D, 7rl7:E, 7rl7:F, 7rl9:A, 7rl9:B, 7rl9:C, 7rl9:D, 7rl9:E, 7rl9:F, 7rla:A, 7rla:F, 7rla:B, 7rla:C, 7rla:D, 7rla:E, 7rlb:A, 7rlb:B, 7rlb:C, 7rlb:D, 7rlb:E, 7rlb:F, 7rlc:A, 7rlc:B, 7rlc:C, 7rlc:D, 7rlc:E, 7rlc:F, 7rld:A, 7rld:B, 7rld:C, 7rld:D, 7rld:E, 7rld:F, 7rlf:A, 7rlf:B, 7rlf:C, 7rlf:D, 7rlf:E, 7rlf:F, 7rlg:A, 7rlg:B, 7rlg:C, 7rlg:D, 7rlg:E, 7rlg:F, 7rlh:A, 7rlh:B, 7rlh:C, 7rlh:D, 7rlh:E, 7rlh:F, 7rli:A, 7rli:B, 7rli:C, 7rli:D, 7rli:E, 7rli:F, 7rli:G, 7rli:H, 7rli:I, 7rli:J, 7rli:K, 7rli:L, 7rlj:A, 7rlj:B, 7rlj:C, 7rlj:D, 7rlj:E, 7rlj:F, 7rlj:L, 7rlj:G, 7rlj:H, 7rlj:I, 7rlj:J, 7rlj:K, 8rsb:A, 8rsb:B, 8rsb:C, 8rsb:D, 8rsb:E, 8rsb:F, 8rsc:A, 8rsc:B, 8rsc:C, 8rsc:D, 8rsc:E, 8rsc:F, 1s3s:A, 1s3s:B, 1s3s:C, 1s3s:D, 1s3s:E, 1s3s:F, 3tiw:A, 3tiw:B, 8uv2:A, 8uv2:B, 8uv2:C, 8uv2:D, 8uv2:E, 8uv2:F, 8uvo:A, 8uvo:B, 8uvo:C, 8uvo:D, 8uvo:E, 8uvo:F, 8uvp:A, 8uvp:B, 8uvp:C, 8uvp:D, 8uvp:E, 8uvp:F, 8uvq:A, 8uvq:B, 8uvq:C, 8uvq:D, 8uvq:E, 8uvq:F, 7vcs:B, 7vcs:C, 7vcs:D, 7vcs:E, 7vcs:F, 7vcs:G, 7vcs:H, 7vcs:I, 7vcs:J, 7vcs:K, 7vcs:L, 7vct:A, 7vct:B, 7vct:C, 7vct:D, 7vct:E, 7vct:F, 7vcu:K, 7vcu:B, 7vcu:C, 7vcu:D, 7vcu:E, 7vcu:F, 7vcu:A, 7vcu:L, 7vcu:G, 7vcu:H, 7vcu:I, 7vcu:J, 7vcv:A, 7vcv:F, 7vcv:E, 7vcv:D, 7vcv:C, 7vcv:B, 7vcx:A, 7vcx:B, 7vcx:C, 7vcx:D, 7vcx:E, 7vcx:F, 7wub:A, 7wub:B, 7wub:C, 7wub:D, 7wub:E, 7wub:F, 7wub:G, 7wub:H, 7wub:I, 7wub:J, 7wub:K, 7wub:L, 7y4w:A, 7y4w:B, 7y4w:E, 7y4w:F, 7y53:A, 7y53:B, 7y53:C, 7y53:D, 7y53:E, 7y53:F, 7y59:A, 7y59:B, 7y59:C, 7y59:D, 7y59:E, 7y59:F
22 7ln6:F 714 28 0.0625 0.0182 0.4643 7.2 3cf0:A, 3cf0:B, 3cf0:C, 3cf0:D, 3cf0:E, 3cf0:F, 3cf0:G, 3cf0:H, 3cf0:I, 3cf0:J, 3cf0:K, 3cf0:L, 3cf0:M, 3cf0:N, 6g2v:A, 6g2w:A, 6g2x:A, 6g2y:A, 6g2z:A, 6g30:A, 7lmz:F, 7ln0:F, 7ln1:F, 7ln2:F, 7ln3:F, 7ln4:F, 7ln5:F, 6mck:A, 6mck:B, 6mck:C, 6mck:D, 6mck:E, 6mck:F, 6mck:G, 6mck:H, 6mck:I, 6mck:J, 6mck:K, 6mck:L, 8vku:A, 8vku:B, 8vku:C, 8vku:D, 8vku:E, 8vku:F, 8vls:A, 8vls:B, 8vls:C, 8vls:D, 8vls:E, 8vls:F, 8vls:G, 8vls:H, 8vls:I, 8vls:J, 8vls:K, 8vls:L, 8vov:A, 8vov:B, 8vov:C, 8vov:D, 8vov:E, 8vov:F
23 5ifw:B 702 28 0.0625 0.0185 0.4643 7.3
24 6fvt:I 385 28 0.0577 0.0312 0.4286 7.7 6ef0:I, 6ef1:I, 6ef2:I, 6ef3:I, 6fvu:I, 6fvv:I, 6fvw:I, 6fvx:I, 6fvy:I, 5mp9:I, 5mpa:I, 5mpb:I, 5mpc:I, 7qo4:I, 7qo5:I, 7qo6:I
25 6ugd:E 312 26 0.0625 0.0417 0.5000 8.6 6b5d:A, 6ugd:A, 6ugd:B, 6ugd:C, 6ugd:D, 6ugd:F, 6uge:B, 6uge:C, 6uge:D, 6uge:E, 6uge:F, 6ugf:B, 6ugf:C, 6ugf:D, 6ugf:E, 6ugf:F, 5wc0:A, 5wc0:B, 5wc0:C, 5wc0:D, 5wc0:E, 5wc0:F, 5wcb:B, 5wcb:C, 5wcb:D, 5wcb:E, 5wcb:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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