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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KGWKFQGEQGEFRLEQPEHNSYLYFPLVNEAGMMSAVTPNLHGEITSGHNTFLMEPVSAESLHNSKASRNFWVFIEGYGA
WSVSGNSARQNAARFTGEEERSAVEAGFLWHAVTRENEKAGLKARTVSFVPVTDDKIELMRVTLTNTGNAPLKLTPTAAI
PLYGRSADDLRDHRHVTSLLHRIFTSEYGIEVQPALSFDERGHRVNKVTYGVFGAEAGGTAPAGFFPVTEDFIGEGGALD
WPEAVVANREPDAQAGTAVEGYEAVGALRFAPVELAPGKSVSYVVAMVISGDRIDVGRYAADYLAAGRFDALLEQNRAYW
RDKLDTVRFSSGDGEQDLWMKWVTLQPILRRLYGNSFLPYHDYGRGGRGWRDLWQDCLALMVMEPAEVRHLLLNNYAGVR
MDGSNATIIGAGPGEFVADRPRVWMDHGAWPLMTTLLYLHQSGDLDLLFQPQSYFRDVFVKRCRERDASWTPEQGNKLLT
ADGQIYEGTILEHILLQNIVPFFNVGEHGNIKLEGADWNDGLDLAPERGESVAFTAFYASNLMELSELLLELQKRTGKDS
LDIAEEMALLLDTLGKPISYDSIQEKRSLLDRYYDAVTPRVSGKKLLLDIRKVAEDLKRKADWAVAHLRGSEWIQSKEGY
AWFNGYYNNDGERVEGDHPDGVRMTLTGQVFAIMGGVATDEQTEKISQAVNRYLKDERIGYRLNSRFGGIQQNLGRAFGF
AFGHKENGAMFSHMTVMYANALYKRGFVQEGFEVLDSIYRLSADFENSRIYPGVPEYINERGRGMYTYLTGSASWLLLTQ
LTEVYGVKGRFGDLRLEPKLVQAQFDGSGEAAVETLFAGRMLRVVYRNPQAAEHGQYRVDSVSLNGQSVDCQAGCLIGRS
LIEALPADGVHELIVTLGR

The query sequence (length=899) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gh2:A 908 905 1.0000 0.9901 0.9934 0.0 6gh2:B, 6gh3:A, 6gh3:B
2 3qde:A 811 789 0.1869 0.2072 0.2129 1.01e-16 8ho8:A, 8ho8:B, 3qde:B
3 3s4a:A 822 748 0.1924 0.2105 0.2313 4.08e-16 3s4a:B, 3s4b:A, 3s4b:B, 3s4d:A
4 3acs:A 822 743 0.1858 0.2032 0.2248 2.01e-14 3acs:B, 3act:A, 3act:B, 3afj:A, 3afj:B, 2cqs:A, 2cqs:B, 2cqt:A, 2cqt:B, 3qfy:A, 3qfy:B, 3qfz:A, 3qfz:B, 3qg0:A, 3qg0:B
5 8rf0:A 2780 613 0.1524 0.0493 0.2235 2.77e-14 8rfe:A, 8rfg:A
6 1v7v:A 779 789 0.1846 0.2131 0.2104 2.80e-11 1v7w:A, 1v7x:A
7 4zlf:A 785 247 0.0679 0.0777 0.2470 6.23e-09 4zlg:A, 4zli:A
8 8h2w:B 984 378 0.0968 0.0884 0.2302 2.13e-05 8h2w:A, 5nz8:B
9 5nz8:A 884 215 0.0567 0.0577 0.2372 4.66e-05
10 7ylr:A 326 152 0.0456 0.1258 0.2697 0.87
11 8wo8:A 463 60 0.0211 0.0410 0.3167 2.0
12 8fia:A 1772 87 0.0345 0.0175 0.3563 2.0
13 1isg:A 250 29 0.0156 0.0560 0.4828 2.1 1isg:B, 1ish:A, 1ish:B, 1isi:A, 1isi:B, 1isj:A, 1isj:B, 1ism:A, 1ism:B
14 5tje:G 112 73 0.0222 0.1786 0.2740 2.3
15 3fg2:P 404 51 0.0211 0.0470 0.3725 3.5
16 8q6p:5 321 44 0.0200 0.0561 0.4091 4.5
17 6gw3:A 383 92 0.0300 0.0705 0.2935 5.6 6gw3:B, 6gw3:C, 6gw3:D, 7w6g:C, 7w6g:D
18 5fal:A 435 47 0.0145 0.0299 0.2766 6.7 5fan:A, 4kec:A
19 7w78:B 344 80 0.0245 0.0640 0.2750 7.5 7w7a:B, 7w7a:D, 7w7a:F, 7w7a:H, 7w7b:B, 7w7b:D, 7w7b:F, 7w7b:H, 7w7d:B, 7w7d:D, 7w7d:F, 7w7d:H
20 3azq:A 661 104 0.0356 0.0484 0.3077 7.7 3azq:B
21 7tem:B 405 79 0.0267 0.0593 0.3038 7.8 7tem:A
22 5l3z:A 280 43 0.0167 0.0536 0.3488 8.0 5l4l:A
23 4v8p:BB 386 60 0.0211 0.0492 0.3167 8.0 4v8p:CB, 4v8p:EB, 4v8p:GB
24 8wr4:B 1442 63 0.0256 0.0160 0.3651 8.0
25 8wmm:B 1212 63 0.0256 0.0190 0.3651 8.8 8iyq:A, 8wmh:A, 8wmm:A, 8wmn:A, 8wmn:B, 8wr4:A
26 4uer:b 572 130 0.0367 0.0577 0.2538 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218