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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KGWKFQGEQGEFRLEQPEHNSYLYFPLVNEAGMMSAVTPNLHGEITSGHNTFLMEPVSAESLHNSKASRNFWVFIEGYGA
WSVSGNSARQNAARFTGEEERSAVEAGFLWHAVTRENEKAGLKARTVSFVPVTDDKIELMRVTLTNTGNAPLKLTPTAAI
PLYGRSADDLRDHRHVTSLLHRIFTSEYGIEVQPALSFDERGHRVNKVTYGVFGAEAGGTAPAGFFPVTEDFIGEGGALD
WPEAVVANREPDAQAGTAVEGYEAVGALRFAPVELAPGKSVSYVVAMVISGDRIDVGRYAADYLAAGRFDALLEQNRAYW
RDKLDTVRFSSGDGEQDLWMKWVTLQPILRRLYGNSFLPYHDYGRGGRGWRDLWQDCLALMVMEPAEVRHLLLNNYAGVR
MDGSNATIIGAGPGEFVADRNNIPRVWMDHGAWPLMTTLLYLHQSGDLDLLFQPQSYFRDVFVKRCRERDASWTPEQGNK
LLTADGQIYEGTILEHILLQNIVPFFNVGEHGNIKLEGADWNDGLDLAPERGESVAFTAFYASNLMELSELLLELQKRTG
KDSLDIAEEMALLLDTLGKPISYDSIQEKRSLLDRYYDAVTPRVSGKKLLLDIRKVAEDLKRKADWAVAHLRGSEWIQSK
EGYAWFNGYYNNDGERVEGDHPDGVRMTLTGQVFAIMGGVATDEQTEKISQAVNRYLKDERIGYRLNSRFGGIQQNLGRA
FGFAFGHKENGAMFSHMTVMYANALYKRGFVQEGFEVLDSIYRLSADFENSRIYPGVPEYINERGRGMYTYLTGSASWLL
LTQLTEVYGVKGRFGDLRLEPKLVQAQFDGSGEAAVETLFAGRMLRVVYRNPQAAEHGQYRVDSVSLNGQSVDCQNDGAG
CLIGRSLIEALPADGVHELIVTLGR

The query sequence (length=905) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gh2:A 908 905 1.0000 0.9967 1.0000 0.0 6gh2:B, 6gh3:A, 6gh3:B
2 3qde:A 811 800 0.1912 0.2133 0.2162 3.29e-18 8ho8:A, 8ho8:B, 3qde:B
3 3s4a:A 822 757 0.1945 0.2141 0.2325 1.54e-16 3s4a:B, 3s4b:A, 3s4b:B, 3s4d:A
4 3acs:A 822 750 0.1878 0.2068 0.2267 8.41e-15 3acs:B, 3act:A, 3act:B, 3afj:A, 3afj:B, 2cqs:A, 2cqs:B, 2cqt:A, 2cqt:B, 3qfy:A, 3qfy:B, 3qfz:A, 3qfz:B, 3qg0:A, 3qg0:B
5 8rf0:A 2780 616 0.1514 0.0493 0.2224 5.42e-14 8rfe:A, 8rfg:A
6 1v7v:A 779 763 0.1768 0.2054 0.2097 6.95e-11 1v7w:A, 1v7x:A
7 4zlf:A 785 248 0.0663 0.0764 0.2419 6.79e-09 4zlg:A, 4zli:A
8 8h2w:B 984 378 0.0961 0.0884 0.2302 2.19e-05 8h2w:A, 5nz8:B
9 5nz8:A 884 215 0.0564 0.0577 0.2372 4.94e-05
10 7ylr:A 326 152 0.0453 0.1258 0.2697 0.89
11 8fia:A 1772 87 0.0343 0.0175 0.3563 2.0
12 1isg:A 250 29 0.0155 0.0560 0.4828 2.1 1isg:B, 1ish:A, 1ish:B, 1isi:A, 1isi:B, 1isj:A, 1isj:B, 1ism:A, 1ism:B
13 5tje:G 112 73 0.0221 0.1786 0.2740 2.3
14 3fg2:P 404 51 0.0210 0.0470 0.3725 3.5
15 8q6p:5 321 44 0.0199 0.0561 0.4091 4.3
16 7m4u:e 155 100 0.0298 0.1742 0.2700 5.4 7m4w:e, 7m4x:e, 7m4y:e, 7m4z:e, 7ryf:e, 7ryg:e, 7ryh:e, 7uvv:e, 7uvw:e, 7uvx:e, 7uvy:e, 7uvz:e, 7uw1:e, 6v39:e, 6v3a:e, 6v3b:e, 6v3e:e, 6ypu:f, 6yt9:f
17 5fal:A 435 47 0.0144 0.0299 0.2766 7.0 5fan:A, 4kec:A
18 3azq:A 661 104 0.0354 0.0484 0.3077 7.1 3azq:B
19 8wr4:B 1442 63 0.0254 0.0160 0.3651 7.4
20 5l3z:A 280 43 0.0166 0.0536 0.3488 7.8 5l4l:A
21 8wmm:B 1212 63 0.0254 0.0190 0.3651 8.2 8iyq:A, 8wmh:A, 8wmm:A, 8wmn:A, 8wmn:B, 8wr4:A
22 4v8p:BB 386 60 0.0210 0.0492 0.3167 8.5 4v8p:CB, 4v8p:EB, 4v8p:GB
23 4uer:b 572 130 0.0365 0.0577 0.2538 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218