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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KGITCVMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNASEIEELSIIKELHIRT
VKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGECLSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTN
GDILEATYPAVAKRLYDDWMHDPAVPIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPT
IYKRATPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKNSYNPKAPGTIITKTRDMTKSILTSIVLKRNVTML
DIASTRMLGQVGFLAKVFSIFEELGISVDVVATSEVSISLTLDPSKLWSRELIQQELDHVVEELEKIAVVNLLKGRAIIS
LIGNVQHSSLILERAFHVLYTKGVNVQMISQGASKVNISFIVNEAEAEGCVQALHKSFFESGDLSELLIQ

The query sequence (length=470) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2cdq:A 470 470 1.0000 1.0000 1.0000 0.0 2cdq:B
2 3c1m:C 468 476 0.3596 0.3611 0.3550 2.10e-82 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
3 2j0w:A 447 463 0.3553 0.3736 0.3607 9.65e-64 2j0x:A, 2j0x:B
4 3tvi:E 439 464 0.2851 0.3052 0.2888 6.28e-49 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
5 5yei:C 397 463 0.2660 0.3149 0.2700 1.45e-32 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
6 3aaw:C 392 468 0.2745 0.3291 0.2756 5.81e-29 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
7 3l76:A 585 470 0.2553 0.2051 0.2553 9.65e-25 3l76:B
8 3l76:A 585 53 0.0319 0.0256 0.2830 0.20 3l76:B
9 3ab4:A 370 471 0.2553 0.3243 0.2548 1.11e-19 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
10 2dt9:A 153 149 0.0872 0.2680 0.2752 5.08e-06 2dt9:B
11 4go7:X 165 130 0.0787 0.2242 0.2846 0.010 3s1t:A, 3s1t:B
12 2j4j:F 226 120 0.0681 0.1416 0.2667 0.013 2j4j:A, 2j4j:E, 2j4j:B, 2j4j:D, 2j4j:C, 2j4k:A, 2j4k:B, 2j4k:D, 2j4k:E, 2j4k:F, 2j4l:A, 2j4l:B, 2j4l:C, 2j4l:D, 2j4l:E, 2j4l:F, 2j4l:G, 2j4l:I, 2j4l:J, 2j4l:K, 2j4l:L
13 2re1:A 148 45 0.0340 0.1081 0.3556 0.040
14 2re1:A 148 37 0.0298 0.0946 0.3784 0.091
15 3ek5:A 241 90 0.0574 0.1120 0.3000 0.046 3ek5:B, 3ek5:C, 3ek5:F, 3ek5:E, 3ek5:D
16 2bne:B 238 78 0.0553 0.1092 0.3333 0.084 2bnd:A, 2bnd:B, 2bne:A, 2bnf:A, 2bnf:B, 2v4y:A, 2v4y:E, 2v4y:F, 2v4y:B, 2v4y:D, 2v4y:C
17 2j4k:C 206 154 0.0809 0.1845 0.2468 0.13 2j4l:H
18 4rgp:A 255 59 0.0426 0.0784 0.3390 0.92 4rgp:B
19 8asa:B 282 45 0.0383 0.0638 0.4000 1.2 8asa:A, 8asa:C, 8asa:D, 8asa:E, 8asa:F, 8asa:G, 8asa:H, 8avq:A, 8avq:B, 8avq:C, 8avq:D, 8q8i:A
20 4a7x:C 234 97 0.0511 0.1026 0.2474 3.4 4a7w:A, 4a7w:B, 4a7x:B, 4a7x:D, 4a7x:E
21 3uyy:B 337 149 0.0851 0.1187 0.2685 4.2 3uyy:A, 3uzb:A, 3uzb:B, 3uzb:C, 3uzb:D, 3uzo:A, 3uzo:B
22 3cin:A 382 37 0.0362 0.0445 0.4595 6.8
23 8y9c:B 1609 81 0.0489 0.0143 0.2840 8.7
24 5bv5:D 327 71 0.0511 0.0734 0.3380 8.8 5bv5:A, 5bv5:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218