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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KFSEECRSAAAEWWEGSFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTGRMASHAQGTYEA
EMALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPGHPIYQKWIG
TYGGDWFRQQVEEQINRFDELAENSTEEVRAKMKENFVISSYYEYQFWGMAYRKEGWSD

The query sequence (length=219) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2qcx:B 227 219 0.9954 0.9604 0.9954 2.98e-166 2qcx:A, 1to9:A, 1to9:B, 1yak:A, 1yak:B, 1yak:C, 1yak:D
2 2gm8:A 217 211 0.3242 0.3272 0.3365 2.43e-27 2gm8:B, 2gm8:C, 2gm8:D
3 1z72:B 215 185 0.2100 0.2140 0.2486 1.80e-10
4 1rtw:B 209 217 0.2420 0.2536 0.2442 8.03e-05 1rtw:A, 1rtw:C, 1rtw:D
5 2f2g:A 215 205 0.2055 0.2093 0.2195 1.1 2f2g:B, 2q4x:A, 2q4x:B
6 7yhn:A 415 60 0.0822 0.0434 0.3000 2.9 8otz:KO, 7rro:KO
7 2oba:B 121 109 0.1096 0.1983 0.2202 3.7 2oba:A, 2oba:C, 2oba:D, 2oba:E, 2oba:F
8 3t0u:B 668 86 0.1050 0.0344 0.2674 7.6 1a2v:A, 1a2v:B, 1a2v:C, 1a2v:F, 1a2v:E, 1a2v:D, 1ekm:A, 1ekm:B, 1ekm:C, 4ev2:A, 4ev2:B, 4ev2:C, 4ev2:D, 4ev2:E, 4ev2:F, 4ev5:A, 4ev5:B, 4ev5:C, 4ev5:D, 4ev5:E, 4ev5:F, 4kfd:A, 4kfd:B, 4kfd:C, 4kfd:D, 4kfd:E, 4kfd:F, 4kfe:A, 4kfe:B, 4kfe:C, 4kfe:D, 4kfe:E, 4kfe:F, 4kff:A, 4kff:B, 4kff:C, 3n9h:A, 3n9h:B, 3n9h:C, 3n9h:D, 3n9h:E, 3n9h:F, 3nbb:A, 3nbb:B, 3nbb:C, 3nbb:D, 3nbb:E, 3nbb:F, 3nbj:A, 3nbj:B, 3nbj:C, 3nbj:D, 3nbj:E, 3nbj:F, 2oov:A, 2oov:B, 2oov:C, 2oov:D, 2oov:E, 2oov:F, 2oqe:A, 2oqe:B, 2oqe:C, 2oqe:D, 2oqe:E, 2oqe:F, 3sxx:A, 3sxx:B, 3sxx:C, 3sxx:D, 3sxx:E, 3sxx:F, 3t0u:A, 3t0u:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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