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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPLKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLP
TRYTLDVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF

The query sequence (length=134) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8aaf:M 135 134 1.0000 0.9926 1.0000 2.60e-94 8agt:M, 8agu:M, 8agv:M, 8agw:M, 8agx:M, 8agz:M, 5apn:Z, 5apo:Z, 7azy:O, 7b7d:LV, 8bip:LZ, 8bjq:LZ, 8bn3:N7, 8bqd:AN, 8bqx:AN, 7bt6:Z, 7btb:Z, 6cb1:Z, 8ccs:L, 8cdl:L, 8cdr:L, 8ceh:L, 8cf5:L, 8cg8:L, 8cgn:L, 8civ:L, 8cku:L, 8cmj:L, 5dat:N7, 5dat:n7, 5dc3:N7, 5dc3:n7, 5dge:N7, 5dge:n7, 5dgf:N7, 5dgf:n7, 5dgv:N7, 5dgv:n7, 6elz:Z, 8eub:AZ, 8evp:AZ, 8evq:AZ, 8evr:AZ, 8evs:AZ, 8evt:AZ, 8ewb:AZ, 8ewc:AZ, 5fci:N7, 5fci:n7, 5fcj:N7, 5fcj:n7, 6ft6:Z, 5gak:b, 6gq1:Z, 6gqb:Z, 6gqv:Z, 5h4p:Z, 6hd7:b, 8hfr:Zq, 6hhq:AA, 6hhq:DB, 5i4l:N7, 5i4l:n7, 6i7o:AN, 6i7o:XN, 5it7:ZZ, 3j6x:67, 3j6y:67, 3j77:77, 3j78:77, 3jct:Z, 5jcs:Z, 5juo:EA, 5jup:EA, 5jus:EA, 5jut:EA, 5juu:EA, 8k2d:LZ, 8k82:LZ, 5lyb:N7, 5lyb:n7, 5m1j:Z5, 6m62:Z, 5mc6:AN, 5mei:AA, 5mei:DB, 7mpi:AZ, 7mpj:AZ, 6n8j:Z, 6n8k:Z, 6n8l:Z, 6n8m:m, 6n8n:m, 6n8o:m, 7n8b:AZ, 7nac:Z, 7nad:Z, 5ndg:N7, 5ndg:n7, 5ndv:N7, 5ndv:n7, 5ndw:N7, 5ndw:n7, 7nrc:Lb, 7nrd:Lb, 5obm:N7, 5obm:n7, 7of1:Z, 7oh3:Z, 7ohq:Z, 7ohr:Z, 7ohv:Z, 6oig:Z, 5on6:AA, 5on6:DB, 7osa:eL27, 7osm:eL27, 8p8m:QZ, 8p8n:QZ, 8p8u:QZ, 8pfr:QZ, 6q8y:AN, 6qik:Y, 6qt0:Y, 6qtz:Y, 7r72:Z, 7r7a:Z, 6r84:b, 6r86:b, 6r87:b, 6ri5:Y, 7rr5:LZ, 6rzz:Y, 6s05:Y, 6s47:Ab, 6snt:aq, 6sv4:AN, 6sv4:XN, 6sv4:zN, 6t4q:LZ, 5t62:m, 5t6r:m, 6t7i:LZ, 6t7t:LZ, 6t83:Zy, 6t83:K, 5tbw:AA, 5tbw:DB, 6tb3:AN, 5tga:N7, 5tga:n7, 5tgm:N7, 5tgm:n7, 6tnu:AN, 7too:AL27, 7top:AL27, 7u0h:Z, 4u3m:N7, 4u3m:n7, 4u3n:N7, 4u3n:n7, 4u3u:N7, 4u3u:n7, 4u4n:N7, 4u4n:n7, 4u4o:N7, 4u4o:n7, 4u4q:N7, 4u4q:n7, 4u4r:N7, 4u4r:n7, 4u4u:N7, 4u4u:n7, 4u4y:N7, 4u4y:n7, 4u4z:N7, 4u4z:n7, 4u50:N7, 4u50:n7, 4u51:N7, 4u51:n7, 4u52:N7, 4u52:n7, 4u53:N7, 4u53:n7, 4u55:N7, 4u55:n7, 4u56:N7, 4u56:n7, 4u6f:N7, 4u6f:n7, 7ug6:Z, 7uoo:Z, 7uqb:Z, 7uqz:Z, 6uz7:AZ, 7v08:Z, 4v6i:Ba, 4v7f:Y, 4v88:BZ, 4v88:DZ, 4v8t:Z, 4v8y:BZ, 4v8z:BZ, 8v87:Z, 4v91:Z, 6woo:Z, 6xiq:Z, 6xir:Z, 8y0u:LZ, 6ylg:Z, 6ylh:Z, 6ylx:Z, 6yly:Z, 7z34:Z, 6z6j:LZ, 6z6k:LZ, 7zpq:BY, 7zrs:BY, 7zs5:Ba, 7zuw:BY, 7zux:EY, 7zw0:Lc
2 8c3a:AA 135 134 0.8060 0.8000 0.8060 1.47e-71 8c3a:BU, 8cq7:AA, 8cq7:BU, 8cqw:AA, 8cqw:BU, 8cre:AA, 8cre:BU, 8oeq:AA, 8oeq:BU, 7pzy:AA, 7q08:AA, 7q0f:AA, 7q0p:AA, 7q0r:AA, 8q5i:AA
3 8i9x:LZ 135 134 0.6493 0.6444 0.6493 9.29e-68 8i9y:LZ, 8i9z:LZ, 8ia0:LZ, 7olc:LZ, 7old:LZ, 8oo0:LZ, 8pv1:LZ, 8pv2:LZ, 8pv3:LZ, 8pv4:LZ, 8pv5:LZ, 8pv6:LZ, 8pv7:LZ, 8pv8:LZ, 8pvk:LZ, 8pvl:LZ, 7z3n:LZ, 7z3o:LZ
4 8esq:Z 134 134 0.6343 0.6343 0.6343 1.16e-65 8esr:Z, 8etc:Z, 8eug:Z, 8eui:Z
5 7r81:b1 135 134 0.6418 0.6370 0.6418 2.63e-64
6 4d5y:Z 136 134 0.5597 0.5515 0.5597 3.81e-53 7a01:22, 8a3d:T, 5aj0:AZ, 8b5l:Z, 8b6c:Z, 9bdl:AL27, 9bdn:AL27, 9bdp:AL27, 7bhp:LZ, 8bhf:M1, 8bpo:Y2, 8btk:BZ, 7cpu:LZ, 7cpv:LZ, 4d67:Z, 6d90:Z, 6d9j:Z, 9f1b:BZ, 9f1c:BZ, 9f1d:BZ, 7f5s:LZ, 8fky:LJ, 8fkz:LJ, 8fl2:LJ, 8fl3:LJ, 8fl4:LJ, 8fl6:LJ, 8fl7:LJ, 8fl9:LJ, 8fla:LJ, 8flb:LJ, 8flc:LJ, 8fld:LJ, 8fle:LJ, 8flf:LJ, 6frk:Z, 6ftg:Z, 6fti:Z, 6ftj:Z, 8g5y:LZ, 8g5z:LZ, 8g60:LZ, 8g61:LZ, 8g6j:LZ, 8glp:LZ, 6gz3:AZ, 6gz4:AZ, 6gz5:AZ, 6hcf:Z3, 6hcj:Z3, 6hcm:Z3, 6hcq:Z3, 8idt:i, 8idy:i, 8ie3:i, 8ifd:2T, 8ife:2T, 8ine:i, 8inf:i, 8ink:i, 6ip5:2T, 6ip6:2T, 6ip8:2T, 8ipd:i, 8ipx:i, 8ipy:i, 8ir1:i, 8ir3:i, 3j7o:Z, 3j7p:Z, 3j7q:Z, 3j7r:Z, 3j92:Z, 3jag:Z, 3jah:Z, 3jai:Z, 3jaj:Z, 3jan:Z, 8jdj:e, 8jdk:e, 8jdl:e, 8jdm:e, 8k2c:LZ, 5lks:LZ, 6lqm:i, 6lsr:i, 6lss:i, 7ls1:T2, 7ls2:T2, 6lu8:i, 5lzs:Z, 5lzt:Z, 5lzu:Z, 5lzv:Z, 5lzw:Z, 5lzx:Z, 5lzy:Z, 5lzz:Z, 7mdz:Z, 6mtb:Z, 6mtc:Z, 6mtd:Z, 6mte:Z, 7nfx:Z, 7nwg:Z3, 7nwh:Z, 7nwi:Z, 7o7y:BZ, 7o7z:BZ, 7o80:BZ, 7o81:BZ, 7obr:Z, 8ohd:LZ, 8oj0:LZ, 8oj5:LZ, 8oj8:LZ, 6ole:a, 6olf:a, 6olg:AZ, 6oli:a, 6olz:AZ, 6om0:a, 6om7:a, 7ow7:T, 7oya:Z1, 7oyb:Z1, 7oyc:Z1, 7oyd:Z, 8p2k:BZ, 6p5i:AZ, 6p5j:AZ, 6p5k:AZ, 6p5n:AZ, 8q7z:BZ, 8q87:BZ, 8qfd:Z, 7qgg:a, 8qoi:LZ, 7qvp:LZ, 7qvp:MZ, 7qwq:Z, 7qwr:Z, 7qws:Z, 6qzp:LZ, 6r5q:Z, 6r6g:Z, 6r6p:Z, 6r7q:Z, 8rjb:Z, 8rjc:Z, 8rjd:Z, 8scb:Z, 6sgc:Z2, 6swa:X, 5t2c:T, 6t59:Z3, 7tm3:Z, 7toq:AL27, 7tor:AL27, 7tut:Z, 7ucj:Z, 7uck:Z, 4ug0:LZ, 4ujc:BZ, 4ujd:AZ, 4uje:CZ, 4v6x:CZ, 6w6l:a, 6xa1:LZ, 7xnx:LZ, 7xny:LZ, 8xsx:LZ, 8xsy:LZ, 8xsz:LZ, 6y0g:LZ, 8y0w:LZ, 8y0x:LZ, 6y2l:LZ, 6y57:LZ, 6y6x:LZ, 8yoo:LZ, 8yop:LZ, 6z6l:LZ, 6z6m:LZ, 6z6n:LZ, 7zjw:Lc, 7zjx:Lc, 6zm7:LZ, 6zme:LZ, 6zmi:LZ, 6zmo:LZ, 6zvk:22
7 9bh5:CZ 135 134 0.5522 0.5481 0.5522 3.91e-51 9cai:CZ
8 6zj3:Ln 133 135 0.5597 0.5639 0.5556 3.30e-49
9 8azw:M 134 134 0.5149 0.5149 0.5149 1.23e-48 8b2l:M3, 7qiw:b, 7qiz:b
10 8ip8:CA 136 136 0.4925 0.4853 0.4853 6.42e-44 8ipa:CA, 8ipb:CA, 8jiv:CZ, 4v3p:La, 4v7e:CZ
11 4v8p:AN 143 143 0.5000 0.4685 0.4685 1.44e-39 4v8p:DN, 4v8p:FN, 4v8p:HN
12 4v6w:CZ 134 134 0.5149 0.5149 0.5149 4.28e-39 6xu6:CZ, 6xu7:CZ, 6xu8:CZ
13 8ova:Ba 132 134 0.4254 0.4318 0.4254 6.44e-39 8ove:Ba, 4v8m:Ba
14 8rxh:LY 133 134 0.4328 0.4361 0.4328 1.85e-36 8a3w:Y, 8a98:Y, 6az3:Y, 3jcs:Y, 8ovj:Y, 8rxx:LY, 5t2a:Y
15 5t5h:a 105 134 0.4179 0.5333 0.4179 2.29e-32
16 5xxb:Y 144 126 0.4403 0.4097 0.4683 2.16e-30
17 3j79:1 140 100 0.3507 0.3357 0.4700 2.16e-26 3jbn:A1, 3jbo:A1, 3jbp:A1, 8tpu:A1, 5umd:1
18 8fru:Z 134 134 0.3731 0.3731 0.3731 4.46e-25 8brm:La, 8bsi:La, 8bsj:La, 8btd:La, 8btr:La, 7pwg:Z, 7pwo:Z2
19 5xy3:Z 135 137 0.3582 0.3556 0.3504 8.07e-22
20 8br8:La 119 134 0.3657 0.4118 0.3657 2.56e-21
21 6zu5:LZ0 127 133 0.3731 0.3937 0.3759 7.88e-19
22 6rm3:LZ0 125 121 0.2463 0.2640 0.2727 7.45e-09
23 7qep:N7 118 139 0.3060 0.3475 0.2950 9.31e-06
24 8p5d:LZ0 118 120 0.2313 0.2627 0.2583 0.003 8p60:LZ0, 8p60:KZ0, 7qca:LZ0
25 7olc:LE 194 30 0.0970 0.0670 0.4333 0.13 8i9p:LE, 8i9r:LE, 8i9t:LE, 8i9v:LE, 8i9w:LE, 8i9x:LE, 8i9y:LE, 8i9z:LE, 8ia0:LE, 7old:LE, 8oo0:LE, 8pv1:LE, 8pv2:LE, 8pv3:LE, 8pv4:LE, 8pv5:LE, 8pv6:LE, 8pv7:LE, 8pv8:LE, 8pvk:LE, 8pvl:LE, 7z3n:LE, 7z3o:LE
26 4v4n:A5 81 26 0.0970 0.1605 0.5000 0.21 4v4n:AK, 4v6u:B5, 4v6u:BK
27 7r81:H1 194 28 0.0896 0.0619 0.4286 0.56
28 8hku:L141 86 26 0.0970 0.1512 0.5000 0.63 8hku:L142, 8hkv:L141, 8hkv:L142, 8hky:L141, 8hky:L142, 8hkz:L141, 8hkz:L142, 8hl1:L141, 8hl1:L142, 8hl2:L141, 8hl2:L142, 8hl3:L141, 8hl3:L142, 8hl4:L141, 8hl4:L142, 8hl5:L141, 8hl5:L142
29 7oya:E1 206 69 0.1716 0.1117 0.3333 0.68 7oyb:E1
30 6skf:BM 81 26 0.0896 0.1481 0.4615 0.68 6skf:BN, 6skg:BM, 6skg:BN, 6th6:BM, 6th6:BN
31 5t5h:v 132 92 0.1791 0.1818 0.2609 0.74
32 3j79:I 207 30 0.0821 0.0531 0.3667 0.95 3jbn:AI, 3jbo:AI, 3jbp:AI, 8tpu:AI, 5umd:I
33 8q7z:BM 130 43 0.1269 0.1308 0.3953 1.1 8q87:BM
34 7oyc:E1 214 51 0.1343 0.0841 0.3529 1.7
35 6qps:A 447 40 0.0821 0.0246 0.2750 1.8 6qps:B
36 4v3p:LG 219 133 0.2537 0.1553 0.2556 3.5 8ip8:LB, 8ipa:LB, 8ipb:LB, 4v7e:CE
37 8qfs:A 1183 55 0.1343 0.0152 0.3273 3.9 8qhc:A
38 4o6r:A 489 65 0.1493 0.0409 0.3077 4.2 4o6r:B, 4o6r:C, 4o6r:D
39 9bh5:CE 139 53 0.1418 0.1367 0.3585 4.3 9cai:CE
40 8esq:M 125 28 0.0821 0.0880 0.3929 5.1 8esr:M, 8etc:M, 8etg:M, 8eth:M, 8eti:M, 8etj:M, 8eug:M, 8eui:M, 8eup:M, 8euy:M, 8ev3:M
41 1r6z:Z 499 79 0.1343 0.0361 0.2278 5.7 3mj0:A, 1r6z:P, 1r6z:A, 1t2r:A, 1t2s:A
42 8jiv:CE 175 28 0.0821 0.0629 0.3929 7.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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