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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPL
EDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFRE
KDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLE
SRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDY
WYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMD
NDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF

The query sequence (length=473) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5gub:A 474 473 1.0000 0.9979 1.0000 0.0 5gub:B, 5gub:C, 5gx6:A, 5gx6:B, 5gx6:C, 5gx7:A, 5gx7:B, 5gx7:C, 5gx8:A, 5gx8:B, 6inz:A, 5xs8:A, 5xs8:B, 5xs8:C, 5xs8:D
2 3a09:A 490 467 0.4059 0.3918 0.4111 1.18e-109 3vlu:A, 3vlv:A, 3vlw:A, 3vlw:B, 1y3n:A, 1y3p:A, 1y3q:A
3 5h71:B 492 476 0.3953 0.3801 0.3929 2.70e-107 5h6u:A, 5h6u:B, 5h71:A, 1j1n:A, 1j1n:B, 6jhx:A, 6jhx:B, 1kwh:A, 4tqu:Q, 4xig:Q, 4xtc:Q
4 5g5y:A 494 492 0.2981 0.2854 0.2866 3.16e-37 5g5y:B, 5g5z:A, 5g5z:B, 5g5z:C, 5g5z:D, 5g60:A, 5g60:B, 5g60:C, 5g60:D, 5g61:A, 5g61:B, 5g61:C, 5g61:D, 5g62:A, 5g62:B
5 3omb:A 503 169 0.1247 0.1173 0.3491 3.39e-18
6 3omb:A 503 73 0.0486 0.0457 0.3151 0.041
7 7ehq:A 406 207 0.1099 0.1281 0.2512 0.014 7ehu:A
8 4r9f:A 402 104 0.0655 0.0771 0.2981 0.035 4r9g:A, 4r9g:B
9 4r2b:A 395 129 0.0698 0.0835 0.2558 0.040 4r2b:B
10 7qhv:AAA 390 141 0.0803 0.0974 0.2695 0.055 7ofy:A, 7ofy:B, 7qhv:BBB, 8s5b:A, 7yzs:AAA, 7yzu:A
11 4g68:A 392 72 0.0550 0.0663 0.3611 0.15 4g68:B
12 5dvi:A 396 88 0.0529 0.0631 0.2841 0.52 5dvi:B, 5dvj:A, 5dvj:B
13 3gnr:A 478 109 0.0465 0.0460 0.2018 0.53 3wba:A, 3wbe:A
14 5mwk:A 1040 66 0.0423 0.0192 0.3030 0.66 5mqm:A, 5mqn:A
15 7vfq:C 397 73 0.0486 0.0579 0.3151 0.88 7vfq:A, 7vfq:B, 7vfq:D, 7vfr:A
16 6pre:A 386 137 0.0740 0.0907 0.2555 1.5 2i58:A, 2i58:B, 6pql:A, 6pql:B, 6pql:C, 6pql:D, 6pre:B, 6pre:C, 6pre:D, 6prg:A, 6prg:B
17 4rk9:A 384 71 0.0486 0.0599 0.3239 2.5 4rk9:B
18 1n04:A 683 53 0.0338 0.0234 0.3019 2.9 2d3i:A, 8fei:A, 1iej:A, 1iq7:A, 1nft:A, 1nnt:A, 1ovt:A, 8x3h:A
19 6gjc:A 2770 49 0.0317 0.0054 0.3061 4.9 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
20 8urw:C 1080 87 0.0529 0.0231 0.2874 6.4 8syi:C
21 3s99:A 330 83 0.0465 0.0667 0.2651 6.5
22 2fni:A 374 42 0.0317 0.0401 0.3571 6.5 2fni:B, 2fnu:A, 2fnu:B
23 3o26:A 294 73 0.0465 0.0748 0.3014 7.4
24 7k78:E 98 53 0.0254 0.1224 0.2264 7.7 7on1:e, 7on1:a, 8ow0:e, 8ow0:a, 8ow1:e, 8ow1:a, 6uph:E
25 4u5k:A 304 143 0.0677 0.1053 0.2238 10.0 4u5i:A, 4u5i:B, 4u5k:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218