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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KEKIDLFYGALLHDIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLGNDHLAYITYIADNIASG
SAKIWDTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQAQIDSLLNL
FEAILSFVPSSTNSKEIADISLAEHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKASAFYEEEAFLLASFDLSGIQDFIY
NIATSGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANLLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTR
LYVAFGWGSFAAKDIMSELNSPESYRQIYQKASRMISEKKISRYDYRTLMLLNRGGKSSERECEICHSVENLVSYHDQKV
CDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQESFSRVYVKNDYKAGTIKATHVFVGDYQCDEIHKY
AALSKNEDGLGIKRLAVVRLDVDDLGAAFMAGFSRQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDD
VFAIGSWQDIIAFTVELRQNFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRF
ITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNYESEEKMNVARLAYYLTRLEELTDKDERDKFKQFKKLFFKWYTN
NESDRKEAELALLLYVYEIRK

The query sequence (length=741) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6nud:J 741 741 1.0000 1.0000 1.0000 0.0 6ifk:A, 6ifn:A, 6ify:A, 6ifz:A, 6ig0:A, 6nue:J
2 6ifu:A 706 744 0.9042 0.9490 0.9005 0.0
3 6ifr:A 694 742 0.8893 0.9496 0.8881 0.0 6ifl:A
4 8wfx:A 801 805 0.4305 0.3983 0.3963 0.0
5 9ash:A 753 778 0.4170 0.4104 0.3972 8.99e-170 9asi:A, 6xn3:A, 6xn4:A, 6xn5:A, 6xn7:A
6 7v00:F 695 750 0.3603 0.3842 0.3560 1.65e-140 7v01:F
7 7v02:F 650 740 0.3455 0.3938 0.3459 2.08e-133
8 6kc0:A 674 768 0.3117 0.3427 0.3008 5.87e-93 6kbd:A
9 6muu:A 780 730 0.2524 0.2397 0.2562 5.24e-57 6iqw:A, 6mur:A, 6mus:A, 6mut:A, 6o7e:A, 6o7h:A
10 6o7i:A 741 755 0.2632 0.2632 0.2583 5.29e-55
11 6o75:A 710 709 0.2429 0.2535 0.2539 4.28e-49 6o74:A, 6o78:A, 6o79:A, 6o7b:A, 6o7d:A
12 4doz:A 557 266 0.0850 0.1131 0.2368 6.73e-05 3ung:C, 3ur3:C
13 3w2w:A 618 231 0.0769 0.0922 0.2468 8.66e-04 4h4k:C, 3w2v:A
14 4w8y:A 835 216 0.0715 0.0635 0.2454 0.012 4w8y:B
15 3x1l:A 573 166 0.0580 0.0750 0.2590 0.086
16 3csl:A 753 182 0.0567 0.0558 0.2308 0.20 3csl:B, 3ddr:A, 3ddr:B
17 1i9z:A 336 75 0.0283 0.0625 0.2800 2.8
18 6npa:A 188 57 0.0256 0.1011 0.3333 2.9 6npa:B, 6npa:C, 6npa:D
19 6zhp:B 341 36 0.0202 0.0440 0.4167 4.7 7fdy:A, 7fdy:B, 7fdy:C, 7ff7:A, 7ff7:B, 7ff7:C, 3fyx:A, 4gcp:A, 4gcp:B, 4gcq:A, 4gcq:B, 4gcs:A, 1gfm:A, 1gfn:A, 1gfo:A, 1gfp:A, 1gfq:A, 4lse:A, 4lse:B, 4lse:C, 4lsi:A, 4lsi:B, 4lsi:C, 1mpf:A, 5nuo:C, 5nuo:A, 5nuo:E, 5nuq:A, 5nuq:B, 5nuq:D, 5nuq:F, 5nur:E, 5nur:C, 5nur:A, 3o0e:A, 3o0e:F, 3o0e:C, 3o0e:D, 3o0e:E, 3o0e:B, 2omf:A, 2zfg:A, 6zhv:B, 6zhv:A, 6zhv:C, 2zld:A, 2zld:B
20 9ayh:A 1056 70 0.0202 0.0142 0.2143 6.5 9ayg:A, 9ayj:A, 9ayk:A, 9ayl:A
21 6i7p:A 883 104 0.0297 0.0249 0.2115 8.8 5goz:A, 5goz:B, 5goz:C, 5gp1:A, 5gp1:B, 5gp1:C, 6i7p:B, 6i7p:C, 6i7p:D, 6i7p:E, 6i7p:F, 5kqr:A, 5kqs:A, 5m2x:A, 5m2x:B, 5m2x:C, 5m2x:D, 5m2x:E, 5m2x:F, 5m2z:A, 5m2z:C, 5m2z:B, 5m2z:D, 5m2z:E, 5m2z:F, 5m5b:A, 5m5b:B, 5mrk:A, 5mrk:B, 5nju:A, 5nju:B, 5njv:A, 5njv:B, 5njv:C, 5njv:D, 8pem:A, 5tfr:A, 5tfr:B, 5tmh:A, 5tmh:B, 5u0b:A, 5u0b:B, 5u0c:A, 5u0c:B, 5u0c:C, 5u0c:D, 5u0c:E, 5u0c:F, 5u0c:G, 5u0c:H, 5ulp:A, 5ulp:B, 6ux2:B, 5vim:A, 5vim:B, 6wcz:B, 5wxb:A, 5wz1:A, 5wz1:B, 5wz1:C, 5wz1:D, 5wz1:E, 5wz1:F, 5wz1:G, 5wz1:H, 5wz2:A, 5wz2:B, 5wz2:C
22 6s6b:K 1024 37 0.0189 0.0137 0.3784 9.1 6s8b:K, 6s8e:K, 6s91:K, 6sh8:K, 6shb:K, 6sic:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218