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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KDLAFPTAEELRTTCKRKRLIPQNNSYFLYLRCKSCDIIILAYSHSQTRRTCPGCNMVMLMPKGGKARIEGDVKIKKIKR

The query sequence (length=80) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6zu5:SBB 80 80 1.0000 1.0000 1.0000 7.05e-56
2 7qep:D7 82 80 0.4375 0.4268 0.4375 1.12e-20
3 8p5d:SBB 81 72 0.3750 0.3704 0.4167 1.61e-17 8p60:SBB, 8p60:RBB, 7qca:SBB
4 6rm3:SBB 82 77 0.4125 0.4024 0.4286 2.58e-17
5 8br8:Se 80 73 0.3625 0.3625 0.3973 2.55e-14 8brm:Se, 8bsi:Se, 8bsj:Se, 8btd:Se, 8btr:Se, 8fvy:b, 8g4s:b, 7pwf:b, 7pwo:b1
6 8jiw:Bb 86 68 0.3875 0.3605 0.4559 7.48e-14 8auv:K, 8b2l:K1, 8ip8:xa, 8ip9:xa, 8ipa:xa, 8ipb:xa, 8r6f:b, 4v3p:SX, 4v7e:Bb
7 8ova:AW 85 68 0.3375 0.3176 0.3971 1.22e-13 7ase:S, 5opt:S, 8ove:AW, 4v8m:AW
8 8rxh:Sc 85 71 0.3625 0.3412 0.4085 6.32e-13 8a3w:Sc, 8a98:Sc, 6az1:c, 8ovj:Sc, 8rxx:Sc, 5t2a:AW
9 5xxu:b 79 76 0.3375 0.3418 0.3553 2.87e-12
10 4v6w:Ab 84 69 0.3250 0.3095 0.3768 3.85e-12 6xu6:Ab, 6xu7:Ab, 6xu8:Ab
11 6zj3:Sc 84 76 0.3250 0.3095 0.3421 5.22e-12
12 4bts:A6 80 76 0.3375 0.3375 0.3553 5.71e-12 4bts:B6, 4bts:C6, 4bts:D6, 4v5o:A6, 4v5o:B6
13 5xyi:b 82 75 0.3375 0.3293 0.3600 6.68e-12
14 5it7:b 82 77 0.3375 0.3293 0.3506 1.01e-11 7a1g:f, 7ajt:Db, 7aju:Db, 7b7d:f, 8bn3:D7, 8bqd:f, 8bqx:f, 8c00:f, 8c01:f, 8c83:f, 8cah:f, 8cas:f, 8cbj:b, 8ccs:3, 8cdl:3, 8cdr:3, 8ceh:3, 8cf5:3, 8cg8:3, 8cgn:3, 8civ:3, 8cku:3, 8cmj:3, 7d4i:Sc, 7d5t:Sc, 7d63:Sc, 5dat:D7, 5dat:d7, 5dc3:D7, 5dc3:d7, 5dge:D7, 5dge:d7, 5dgf:D7, 5dgf:d7, 5dgv:D7, 5dgv:d7, 6eml:f, 8eub:Bb, 8evp:Bb, 8evq:Bb, 8evr:Bb, 8evs:Bb, 8evt:Bb, 8ewb:Bb, 8ewc:Bb, 6fai:b, 5fci:D7, 5fci:d7, 5fcj:D7, 5fcj:d7, 6fyx:b, 6fyy:b, 6gq1:AR, 6gqb:AR, 6gqv:AR, 6gsm:b, 6gsn:b, 6hhq:c, 6hhq:d7, 5i4l:D7, 5i4l:d7, 6i7o:f, 6i7o:fb, 8i7j:b, 5it9:b, 3j6x:27, 3j6y:27, 3j77:27, 3j78:27, 3j80:b, 3j81:b, 3jam:b, 3jap:b, 5juo:YB, 5jup:YB, 5jus:YB, 5jut:YB, 5juu:YB, 8k2d:Sb, 8k82:Sb, 6ke6:Sc, 5ll6:f, 6lqp:Sc, 6lqq:Sc, 6lqr:Sc, 6lqs:Sc, 6lqt:Sc, 5lyb:D7, 5lyb:d7, 5m1j:b2, 5mc6:f, 5mei:d7, 5mei:c, 7mpi:Bb, 7mpj:Bb, 7n8b:Bb, 5ndg:D7, 5ndg:d7, 5ndv:D7, 5ndv:d7, 5ndw:D7, 5ndw:d7, 7nrc:Sf, 7nrd:Sf, 5obm:D7, 5obm:d7, 5on6:d7, 5on6:c, 7osa:eS27, 7osm:eS27, 6q8y:f, 6rbd:b, 6rbe:b, 7rr5:Sb, 8rw1:b, 6s47:Bc, 8s8d:b, 8s8e:b, 8s8f:b, 8s8g:b, 8s8h:b, 8s8i:b, 8s8j:b, 6snt:b, 6sv4:f, 6sv4:fb, 6sv4:fc, 6t4q:Sb, 6t7i:Sb, 6t7t:Sb, 6t83:bb, 6t83:2, 5tbw:c, 5tbw:d7, 6tb3:f, 5tga:D7, 5tga:d7, 5tgm:D7, 5tgm:d7, 6tnu:f, 4u3m:D7, 4u3m:d7, 4u3n:D7, 4u3n:d7, 4u3u:D7, 4u3u:d7, 4u4n:D7, 4u4n:d7, 4u4o:D7, 4u4o:d7, 4u4q:D7, 4u4q:d7, 4u4r:D7, 4u4r:d7, 4u4u:D7, 4u4u:d7, 4u4y:D7, 4u4y:d7, 4u4z:D7, 4u4z:d7, 4u50:D7, 4u50:d7, 4u51:D7, 4u51:d7, 4u52:D7, 4u52:d7, 4u53:D7, 4u53:d7, 4u55:D7, 4u55:d7, 4u56:D7, 4u56:d7, 4u6f:D7, 4u6f:d7, 4uer:6, 6uz7:b, 4v6i:AX, 4v88:Ab, 4v88:Cb, 4v8y:A1, 4v8z:A1, 4v92:Bb, 6wdr:b, 6woo:bb, 7wtl:Sb, 7wtm:Sb, 7wtn:Sb, 7wto:Sb, 7wtp:Sb, 7wtq:Sb, 7wtr:Sb, 5wyj:Sc, 5wyk:Sc, 6xiq:AR, 6xir:AR, 8y0u:Sb, 6y7c:b, 6z6j:Sb, 6z6k:Sb, 6zce:c, 7zpq:Ab, 6zqa:Db, 6zqb:Db, 6zqc:Db, 6zqd:Db, 6zqe:Db, 6zqf:Db, 6zqg:Db, 7zrs:Ab, 6zu9:f, 7zuw:Ab, 7zux:Db, 6zvi:L, 7zw0:sf
15 6fec:Y 84 69 0.3875 0.3690 0.4493 1.48e-11 7a01:L3, 7a09:R, 5a2q:b, 5aj0:Bb, 9bdl:AS27, 9bdn:AS27, 9bdp:AS27, 8bhf:c3, 9bkd:H, 9bln:H, 8btk:AA, 7cpu:Sb, 7cpv:Sb, 4d5l:b, 4d61:b, 6d90:cc, 6d9j:cc, 9f1b:AA, 9f1c:AA, 9f1d:AA, 5flx:b, 6g18:b, 6g4s:b, 6g4w:b, 6g51:b, 6g53:b, 6g5h:b, 6g5i:b, 8g5y:Sb, 8g5z:Sb, 8g60:Sb, 8g61:Sb, 8g6j:Sb, 8glp:Sb, 6gz3:Bb, 6gz4:Bb, 6gz5:Bb, 6hcf:c1, 6hcj:c2, 6hcm:c1, 6hcq:c2, 8ifd:3P, 8ife:3P, 6ip5:3P, 6ip6:3P, 6ip8:3P, 3j7p:Sb, 3j7r:Sb, 3jag:bb, 3jah:bb, 3jai:bb, 3jaj:Sb, 3jan:Sb, 8jdj:AN, 8jdk:AN, 8jdl:AN, 8jdm:AN, 7jqb:e, 7jqc:e, 5k0y:Y, 8k2c:Sb, 7k5i:b, 4kzx:b, 4kzy:b, 4kzz:b, 5lks:Sb, 7ls1:S3, 7ls2:S3, 5lzs:bb, 5lzt:bb, 5lzu:bb, 5lzv:bb, 5lzw:bb, 5lzx:bb, 5lzy:bb, 5lzz:bb, 7mdz:bb, 7mq8:NQ, 7mq9:NQ, 7mqa:NQ, 6mtb:bb, 6mtc:bb, 6mtd:bb, 6mte:bb, 7nwg:c2, 7nwh:bb, 7nwi:bb, 7o7y:AA, 7o7z:AA, 7o80:AA, 7o81:AA, 5oa3:b, 6ole:Sb, 6olf:Sb, 6olg:Bb, 6oli:Sb, 6olz:Bb, 6om0:Sb, 6om7:Sb, 7oya:b2, 7oyb:b2, 7oyc:b2, 7oyd:Bb, 8oz0:M, 8p03:c, 8p09:c, 8p2k:AA, 6p4g:c, 6p4h:c, 6p5i:c, 6p5j:c, 6p5k:c, 6p5n:c, 8pj1:H, 8pj2:H, 8pj3:H, 8pj4:H, 8pj5:H, 8pj6:H, 8ppk:b, 8ppl:Ab, 8q7z:AA, 8q87:AA, 7qgg:Sb, 8qoi:Sb, 7qp6:H, 7qp7:H, 7qvp:Sb, 7qvp:Rb, 6qzp:Sb, 7r4x:b, 6r5q:JJ, 6r6g:JJ, 6r6p:JJ, 6r7q:JJ, 8rg0:H, 8scb:bb, 6sgc:c1, 7syg:c, 7syh:c, 7syi:c, 7syj:c, 7syk:c, 7syl:c, 7sym:c, 7syn:c, 7syo:c, 7syp:c, 7syq:c, 7syr:c, 7sys:c, 7syt:c, 7syu:c, 7syv:c, 7syw:c, 7syx:c, 5t2c:AV, 8t4s:b, 7toq:AS27, 7tor:AS27, 7tql:b, 7ucj:Bb, 7uck:Bb, 4ug0:Sb, 4ujc:Cb, 4ujd:Cb, 4uje:Bb, 4v6x:Ab, 5vyc:b1, 5vyc:b2, 5vyc:b3, 5vyc:b4, 5vyc:b5, 5vyc:b6, 6w2s:c, 6w2t:c, 7wts:b, 7wtt:b, 7wtu:b, 7wtv:b, 7wtw:b, 7wtx:b, 7wtz:b, 7wu0:b, 6xa1:Sb, 7xnx:Sb, 7xny:Sb, 8xsx:Sb, 8xsy:Sb, 8xsz:Sb, 8xxl:Sb, 8xxm:Sb, 8xxn:Sb, 6y0g:Sb, 8y0w:Sb, 8y0x:Sb, 6y2l:Sb, 6y57:Sb, 6yal:c, 6yam:c, 6yan:c, 6ybw:H, 8yoo:Sb, 8yop:Sb, 6z6l:Sb, 6z6m:Sb, 6z6n:Sb, 7zjw:SB, 7zjx:SB, 6zlw:b, 6zm7:Sb, 6zme:Sb, 6zmi:Sb, 6zmo:Sb, 6zmt:b, 6zmw:H, 6zn5:b, 6zoj:b, 6zok:b, 6zon:R, 6zp4:R, 6zuo:b, 6zv6:b, 6zvh:b, 6zvj:R, 6zvk:L3, 6zxd:b, 6zxe:b, 6zxf:b, 6zxg:b, 6zxh:b
16 8c3a:d 81 72 0.3375 0.3333 0.3750 2.49e-11 8c3a:DO, 8cq7:d, 8cq7:DO, 8cqw:d, 8cqw:DO, 8cre:d, 8cre:DO, 8oeq:d, 8oeq:DO, 7pzy:c, 7q08:c, 7q0f:c, 7q0p:c, 7q0r:c, 8q5i:c
17 7olc:Sb 81 71 0.3500 0.3457 0.3944 2.60e-11 7old:Sb, 8oo0:Sb, 7r81:c2, 6rxx:Cq, 7z3n:Sb, 7z3o:Sb
18 3j7a:4 76 62 0.3000 0.3158 0.3871 6.23e-11 3jbn:4, 3jbo:4, 3jbp:4, 6okk:d, 8tpu:S4
19 9bh5:Ab 82 76 0.3375 0.3293 0.3553 1.18e-10 9cai:Ab
20 8hkx:S27E 59 56 0.2625 0.3559 0.3750 7.60e-08 8hky:S27E, 8hkz:S27E, 8hl1:S27E, 8hl2:S27E, 8hl3:S27E, 8hl4:S27E, 8hl5:S27E, 8wkp:S27E, 8wq2:S27E, 8wq4:S27E
21 6sw9:W 63 56 0.2250 0.2857 0.3214 2.92e-05 6swc:W, 6swd:W, 7zag:W, 7zah:W, 7zai:W, 7zhg:W
22 5jb3:W 63 56 0.2125 0.2698 0.3036 8.24e-05 5jbh:W, 4v4n:BW, 4v6u:AW
23 6tmf:Y 63 56 0.2250 0.2857 0.3214 4.17e-04 6skf:Ax, 6skg:Ax, 6th6:Ax
24 6dgd:A 704 73 0.2750 0.0312 0.3014 0.073 6dgd:B, 4nl4:H
25 4nl8:A 549 56 0.2250 0.0328 0.3214 0.092
26 4nl8:E 571 56 0.2250 0.0315 0.3214 0.092 4nl8:B
27 2cm6:A 149 58 0.2125 0.1141 0.2931 0.17 2cm5:A, 2cm6:B, 5lo8:A, 5lo8:B, 5lob:A, 5lob:B, 5lob:C, 5low:A, 5low:B, 5low:C, 5low:H, 5low:I, 5low:J
28 6dcr:B 600 42 0.1875 0.0250 0.3571 0.25
29 8fak:H 643 42 0.1875 0.0233 0.3571 0.25 2d7g:A, 2d7g:B, 2d7g:C, 2d7g:D, 2d7h:A, 6dcr:A, 2dwl:A, 2dwl:B, 2dwl:C, 2dwl:D, 2dwm:A, 2dwm:C, 2dwm:D, 2dwn:A, 2dwn:C
30 7qix:V 68 71 0.3250 0.3824 0.3662 0.74 7qiz:LA
31 1xfu:A 735 39 0.1250 0.0136 0.2564 2.8 1k90:A, 1k90:C, 1lvc:A, 1lvc:C, 1pk0:A, 1pk0:C, 1s26:A, 1s26:C, 1sk6:C, 1xfu:B, 1xfu:C, 1xfu:D, 1xfu:E, 1xfu:F, 1xfv:A, 1xfv:B, 1xfv:C, 1xfv:D, 1xfv:E, 1xfv:F, 1xfw:A, 1xfw:B, 1xfw:C, 1xfw:D, 1xfw:E, 1xfw:F, 1xfx:A, 1xfx:B, 1xfx:C, 1xfx:D, 1xfx:E, 1xfx:F, 1xfy:A, 1xfy:B, 1xfy:C, 1xfy:D, 1xfy:E, 1xfy:F, 1xfz:A, 1xfz:B, 1xfz:C, 1xfz:D, 1xfz:E, 1xfz:F, 1y0v:A, 1y0v:B, 1y0v:C, 1y0v:D, 1y0v:E, 1y0v:F
32 7mhd:A 282 34 0.1500 0.0426 0.3529 3.6 7mhe:AAA, 2px6:B, 3tjm:A
33 3j1o:J 159 33 0.1750 0.0881 0.4242 3.6 3rj1:J, 3rj1:Q, 7ui9:h, 7uif:h, 7uig:h, 7uio:Ah, 7uio:Bh
34 8e4y:A 651 50 0.2125 0.0261 0.3400 4.0 8e50:A
35 1sk6:B 454 38 0.1250 0.0220 0.2632 4.2
36 3bh6:B 314 38 0.1625 0.0414 0.3421 4.4 3bh7:B
37 4l1w:A 325 42 0.1750 0.0431 0.3333 4.7 6a7a:A, 3c3u:A, 3gug:A, 2hdj:A, 2hdj:B, 1ihi:A, 1ihi:B, 6ijx:A, 2ipj:A, 2ipj:B, 1j96:A, 1j96:B, 8jp2:A, 4jq1:A, 4jq1:B, 4jq2:A, 4jq2:B, 4jq3:A, 4jq3:B, 4jq4:A, 4jq4:B, 4jqa:A, 4jqa:B, 4jtq:A, 4jtq:B, 4jtr:A, 4jtr:B, 4l1w:B, 4l1x:A, 4l1x:B, 1mrq:A, 3nty:A, 1xjb:A, 1xjb:B, 4xo6:A, 4xo6:B, 4xo7:A, 4xo7:B, 4yvp:A, 4yvp:B
38 1sk6:A 481 36 0.1250 0.0208 0.2778 6.6 1k90:B, 1pk0:B, 1s26:B
39 3cv6:A 323 42 0.1750 0.0433 0.3333 6.7 3cv6:B, 2he5:A, 2he5:B, 2he5:C, 2he5:D, 2hej:A, 2hej:B, 2ipf:A, 2ipf:B, 2ipg:A, 2ipg:B, 2p5n:A, 2p5n:B
40 8pmq:9 412 43 0.1625 0.0316 0.3023 6.8
41 6u7l:A 460 40 0.1750 0.0304 0.3500 7.7 6u7l:B, 6u7l:C, 6u7l:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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