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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
KATLPDLKYDYGALEPYISARIMELHHSKHHQTYVNGLNSALEATAEAEAKGDFTKAASLAPLLNFHGGGHLNHTLFWEN
LAPASREGGGEPDGALKKAIEADFGSFETFRKQMNAALTGIQGSGWAWLAKDKDSGNLAIVTRANQDPVTGQLVPLMGID
AWEHAYYLQYENRKAEYFEAIWNVINWKTVAQRFEK

The query sequence (length=196) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4br6:B 197 196 1.0000 0.9949 1.0000 1.07e-146 4br6:A, 4br6:C, 4br6:D
2 7kks:A 199 196 0.5765 0.5678 0.5765 2.06e-82 2adp:A, 2adq:B, 1ap5:A, 1ap5:B, 1ap6:A, 1ap6:B, 3c3s:A, 3c3s:B, 3c3t:A, 3c3t:B, 1em1:A, 1em1:B, 2gds:A, 2gds:B, 2gds:C, 2gds:D, 5gxo:A, 5gxo:B, 1ja8:A, 1ja8:B, 7kks:B, 7kku:A, 7kku:B, 7kkw:A, 7kkw:B, 7klb:A, 7klb:B, 1luv:A, 1luv:B, 1luw:A, 1luw:B, 1msd:A, 1msd:B, 1n0j:A, 1n0j:B, 1n0n:A, 1n0n:B, 2p4k:A, 2p4k:B, 2p4k:C, 2p4k:D, 1pl4:A, 1pl4:B, 1pl4:C, 1pl4:D, 1pm9:A, 1pm9:B, 2qka:A, 2qka:C, 2qkc:A, 2qkc:C, 1qnm:A, 1qnm:B, 8sks:A, 8sks:B, 8sks:C, 8sks:D, 1szx:A, 1szx:B, 5t30:A, 5t30:B, 1var:A, 1var:B, 5vf9:A, 5vf9:B, 8vhw:A, 8vhw:B, 8vhy:A, 8vhy:B, 8vj0:A, 8vj0:B, 8vj4:A, 8vj4:B, 8vj5:A, 8vj5:B, 8vj8:A, 8vj8:B, 1xdc:A, 1xdc:B, 1xil:A, 1xil:B, 1zsp:A, 1zsp:B, 1zte:A, 1zte:B, 1zte:C, 1zte:D, 1zuq:A, 1zuq:B
3 4e4e:B 207 203 0.5663 0.5362 0.5468 6.78e-78 3bfr:A, 4e4e:A, 4e4e:C, 4e4e:D, 4f6e:A, 4f6e:B, 4f6e:C, 4f6e:D, 3lsu:A, 3lsu:B, 3lsu:C, 3lsu:D, 3rn4:A
4 4c7u:A 203 197 0.5459 0.5271 0.5431 9.66e-77 4c7u:B, 4c7u:C, 4c7u:D, 4c7u:E, 4c7u:F, 4c7u:G, 4c7u:H
5 1kkc:A 200 194 0.5663 0.5550 0.5722 4.21e-74 1kkc:B, 1kkc:X, 1kkc:Y
6 3dc6:C 198 198 0.5357 0.5303 0.5303 8.33e-73 3dc6:A
7 5ag2:C 195 194 0.5153 0.5179 0.5206 5.24e-71 5ag2:A, 3dc5:A, 3dc5:C, 6elk:A, 6elk:C, 6qzm:A, 6qzm:C, 6qzn:A, 6qzn:C, 6s0d:A, 6s0d:C, 4x9q:A, 4x9q:C
8 6cyp:A 211 195 0.5459 0.5071 0.5487 8.26e-68 6cyl:A, 6cyl:B, 6cyl:C, 6cyl:D, 6cyp:B, 6cyp:C, 6cyp:D, 6cyp:E, 6cyp:F, 6cys:A, 6cys:B, 6cys:C, 6cys:D, 6cyx:A, 6cyx:B, 6cyx:C, 6cyx:D, 6cyx:E, 6cyx:F, 6dqy:A, 6dqy:B, 6dqy:C, 6dqy:D, 6dqy:E, 6dqy:F, 6dqy:G, 6dqy:H, 6dqy:I, 6dqy:J, 6dqy:K, 6dqy:L, 6dqy:M, 6dqy:N, 6dqy:O, 6dqy:P, 6dqy:Q, 6dqy:R, 6dqy:S, 6dqy:T, 6dqy:U, 6dqy:V, 6dqy:W, 6dqy:X, 7svs:A, 7svs:B, 7svs:C, 7svs:D, 7svs:E, 7svs:F, 7svs:G, 7svs:H, 5tir:A, 5tir:B, 5tir:C, 5tir:D
9 4gun:A 205 198 0.5102 0.4878 0.5051 8.77e-67 4gun:B, 4gun:C, 4gun:D, 4gun:E, 4gun:F, 4gun:G, 4gun:H, 4gun:I, 4gun:J, 4gun:K, 4gun:L, 4gun:M, 4gun:N, 4gun:O, 4gun:P, 3qvn:A
10 8bhx:A 203 194 0.5357 0.5172 0.5412 4.57e-66 8bhx:B
11 1ar4:A 201 197 0.4898 0.4776 0.4873 6.51e-59 1ar4:B, 1ar5:A, 1ar5:B, 1avm:A, 1avm:B, 1bs3:A, 1bs3:B, 1bsm:A, 1bsm:B, 1bt8:A, 1bt8:B
12 3mds:A 203 201 0.4796 0.4631 0.4677 2.89e-58 3mds:B, 1mng:A, 1mng:B
13 6bej:E 201 200 0.4847 0.4726 0.4750 1.25e-57 6bej:A
14 1gn2:A 198 193 0.4796 0.4747 0.4870 6.22e-57 1gn2:B, 1gn2:C, 1gn2:D, 1gn2:E, 1gn2:F, 1gn2:G, 1gn2:H, 1gn3:A, 1gn3:B, 1gn4:A, 1gn4:B, 1gn4:C, 1gn4:D, 1gn6:A, 1gn6:B, 1gn6:C, 1gn6:D, 1ids:A, 1ids:B, 1ids:C, 1ids:D
15 6pro:A 202 201 0.4694 0.4554 0.4577 1.16e-56 6pro:B
16 1gv3:A 213 202 0.4541 0.4178 0.4406 8.55e-55 1gv3:B
17 2rcv:A 200 201 0.4643 0.4550 0.4527 1.22e-54 2rcv:B, 2rcv:C, 2rcv:D, 2rcv:E, 2rcv:F, 2rcv:G, 2rcv:H
18 1y67:D 214 207 0.4745 0.4346 0.4493 1.44e-54 2aw9:A, 2aw9:B, 2cdy:A, 2cdy:B, 2cdy:C, 2cdy:D, 2ce4:A, 2ce4:B, 3kky:A, 3kky:B, 1y67:A, 1y67:B, 1y67:C
19 1xuq:A 200 204 0.4541 0.4450 0.4363 3.18e-54 1xuq:B
20 1ma1:A 201 194 0.4541 0.4428 0.4588 4.03e-54 1ma1:B, 1ma1:C, 1ma1:D, 1ma1:E, 1ma1:F
21 6ex4:A 198 199 0.4388 0.4343 0.4322 2.40e-52 6ex4:B, 6ex5:A, 6ex5:B, 5n57:A, 5n57:B, 6qv8:A, 6qv8:B
22 8kb3:A 206 207 0.4694 0.4466 0.4444 1.03e-51 1d5n:A, 1d5n:B, 1d5n:C, 1d5n:D, 1en4:A, 1en4:B, 1en4:C, 1en4:D, 1en5:A, 1en5:B, 1en5:C, 1en5:D, 1en6:A, 1en6:B, 1en6:C, 1en6:D, 1i08:A, 1i08:B, 1i08:C, 1i08:D, 1i0h:A, 1i0h:B, 1ix9:A, 1ix9:B, 3k9s:A, 3k9s:B, 3k9s:C, 3k9s:D, 8kb3:B, 1mmm:A, 1mmm:B, 1vew:A, 1vew:B, 1vew:C, 1vew:D, 1zlz:B
23 8avl:A 192 193 0.4592 0.4688 0.4663 9.12e-51 8avl:B, 8avl:C, 8avl:D, 8avl:E, 8avl:F, 8avl:G, 8avl:H, 8avm:A, 8avm:B, 8avm:C, 8avm:D, 8avm:E, 8avm:F
24 8avk:A 202 201 0.4286 0.4158 0.4179 1.33e-50 8avk:B, 8avn:A, 8avn:B
25 1xre:A 201 199 0.4133 0.4030 0.4070 3.79e-50 1xre:B
26 7wnk:D 202 199 0.4388 0.4257 0.4322 5.83e-50 7ddw:A, 7ddw:B, 7ddw:C, 7ddw:D, 7ddw:E, 7ddw:F, 6m30:A, 6m30:B, 6m30:C, 6m30:D, 6m30:E, 6m30:F, 7w6w:A, 7w6w:B, 7w6w:D, 7wnk:A, 7wnk:B, 7wnk:C, 7wnl:A, 7wnl:B, 7wnl:C, 7wnl:D, 5x2j:A
27 5n56:A 198 199 0.4337 0.4293 0.4271 6.87e-50 6ex3:A, 6ex3:B, 6ex3:C, 6ex3:D, 5n56:B, 6qv9:A, 6qv9:B, 7w6w:C
28 1jr9:A 201 204 0.4337 0.4229 0.4167 7.43e-50
29 4yip:A 203 198 0.4694 0.4532 0.4646 1.12e-49 4yip:B, 4yip:C, 4yip:D
30 4yio:A 202 198 0.4592 0.4455 0.4545 2.88e-49 4yio:B
31 4jyy:A 202 203 0.4235 0.4109 0.4089 1.62e-48 4jz2:A, 4jzg:A, 3tjt:A
32 5a9g:A 206 197 0.4337 0.4126 0.4315 1.17e-47 5a9g:B, 6gsb:A, 6gsb:B, 6gsc:A, 6gsc:B
33 1dt0:A 197 203 0.4235 0.4213 0.4089 4.57e-46 1dt0:B, 1dt0:C, 3sdp:A, 3sdp:B
34 3ak3:B 213 195 0.4388 0.4038 0.4410 6.39e-46 3ak2:A, 3ak2:B, 3ak2:C, 3ak2:D, 3ak3:A, 3ak3:C, 3ak3:D
35 2cw2:A 199 205 0.4337 0.4271 0.4146 1.00e-45 2cw2:B
36 3tqj:A 192 194 0.3980 0.4062 0.4021 1.99e-45 3tqj:B
37 2bkb:A 192 199 0.4235 0.4323 0.4171 5.51e-45 2bkb:B, 2bkb:C, 2bkb:D, 1isa:A, 1isa:B, 1isb:A, 1isb:B, 1isc:A, 1isc:B, 2nyb:A, 2nyb:B, 2nyb:C, 2nyb:D, 1za5:A, 1za5:B
38 2bpi:A 197 196 0.3878 0.3858 0.3878 1.38e-44 2bpi:B
39 3evk:A 211 197 0.4184 0.3886 0.4162 1.14e-43 3evk:B, 3evk:C, 3evk:D
40 1qnn:A 191 192 0.3980 0.4084 0.4062 1.37e-43 1qnn:B, 1qnn:C, 1qnn:D, 1uer:A, 1uer:B, 1uer:C, 1uer:D, 1ues:A, 1ues:B, 1ues:C, 1ues:D
41 4ffk:A 212 196 0.4235 0.3915 0.4235 2.74e-43
42 3h1s:B 192 195 0.3929 0.4010 0.3949 1.36e-42 3h1s:A
43 2a03:A 197 196 0.3673 0.3655 0.3673 5.48e-42 2a03:B, 2goj:A, 2goj:B
44 1wb7:A 205 201 0.4337 0.4146 0.4229 1.72e-41 1wb7:B, 1wb8:A, 1wb8:B
45 4l2a:A 192 203 0.3980 0.4062 0.3842 1.22e-40 4l2a:B, 4l2b:A, 4l2b:B, 4l2c:A, 4l2c:B, 4l2c:D, 4l2c:C, 4l2d:A, 4l2d:D, 4l2d:C, 4l2d:B, 3lio:A, 3lio:B, 3lj9:B, 3lj9:A, 3ljf:A, 3ljf:C, 3ljf:B, 3ljf:D
46 2gpc:A 194 196 0.3827 0.3866 0.3827 1.59e-40 2gpc:B
47 6jov:C 198 202 0.3980 0.3939 0.3861 2.08e-39 6jov:A, 6jov:B, 6jov:D
48 3cei:A 213 200 0.3724 0.3427 0.3650 9.46e-39 3cei:B
49 8w9z:G 218 198 0.3776 0.3394 0.3737 2.99e-38 8wa0:G, 8wa1:G
50 2w7w:A 193 202 0.4082 0.4145 0.3960 4.68e-38 2w7w:B
51 6j55:L 203 198 0.3776 0.3645 0.3737 5.72e-38 6j55:A, 6j55:B, 6j55:C, 6j55:D, 6j55:E, 6j55:F, 6j55:G, 6j55:H, 6j55:I, 6j55:J, 6j55:K
52 4f2n:B 210 211 0.3776 0.3524 0.3507 3.21e-37 4f2n:A, 4f2n:C, 4f2n:D, 4f2n:E, 4f2n:F, 4f2n:G, 4f2n:H, 4f2n:I, 4f2n:J, 4f2n:K, 4f2n:L
53 3esf:A 197 198 0.3622 0.3604 0.3586 4.30e-37 3esf:B, 3esf:C, 3esf:D
54 1my6:A 198 195 0.3827 0.3788 0.3846 5.85e-37 1my6:B
55 1b06:A 208 201 0.3980 0.3750 0.3881 6.12e-37 1b06:B, 1b06:C, 1b06:D, 1b06:E, 1b06:F
56 4yet:B 200 194 0.3622 0.3550 0.3660 4.70e-36 4yet:A
57 8r6s:N 224 209 0.3724 0.3259 0.3493 8.30e-35 7bjk:A, 7bjk:B, 7bjk:C, 7bjk:D, 7bjk:E, 8qma:L, 8r5o:N, 8ras:N, 8rdj:N
58 8r5o:I 215 199 0.3622 0.3302 0.3568 1.38e-34 8qma:G, 8r6s:I, 8ras:I, 8rdj:I
59 8wa0:L 235 210 0.3724 0.3106 0.3476 1.45e-34 8w9z:L, 8wa1:L
60 4h3e:A 214 208 0.3622 0.3318 0.3413 1.74e-34 4dvh:A, 4dvh:B, 4h3e:B
61 3js4:A 207 205 0.3827 0.3623 0.3659 8.67e-34 3js4:B, 3js4:C, 3js4:D
62 7sbh:A 208 199 0.3878 0.3654 0.3819 4.42e-33
63 2cw3:A 200 196 0.3418 0.3350 0.3418 5.45e-30 2cw3:B
64 7azq:A 199 199 0.3367 0.3317 0.3317 5.49e-30 7azq:E, 7azr:A, 7azr:E
65 1unf:X 214 207 0.3724 0.3411 0.3527 1.22e-28
66 1coj:A 211 187 0.3316 0.3081 0.3476 1.85e-25
67 6yw5:44 260 81 0.1173 0.0885 0.2840 0.005 6ywe:44, 6ywx:44, 6ywy:44
68 6yw5:44 260 51 0.0714 0.0538 0.2745 0.27 6ywe:44, 6ywx:44, 6ywy:44
69 8om2:3 257 183 0.1837 0.1401 0.1967 0.019 8d8k:3, 8d8l:3, 5mrc:33, 5mre:33, 5mrf:33, 8om3:3, 8om4:3
70 7aor:y 253 126 0.1786 0.1383 0.2778 0.071
71 2yeq:A 522 129 0.1480 0.0556 0.2248 0.69 2yeq:B
72 4tlm:D 753 55 0.0969 0.0252 0.3455 1.0
73 4tll:D 757 55 0.0969 0.0251 0.3455 1.0 4tll:B, 4tlm:B, 5un1:B
74 5iov:B 798 55 0.0969 0.0238 0.3455 1.1 5iou:B, 5iou:D, 5iov:D, 5un1:D, 5un1:H
75 7pub:Cr 267 86 0.1173 0.0861 0.2674 1.4 6hiv:Cr, 6hiw:Cr, 6hiy:Cr
76 1frv:A 262 42 0.0612 0.0458 0.2857 1.5 1frv:C, 2frv:S, 2frv:A, 2frv:C, 2frv:E, 2frv:G, 2frv:I, 1yq9:A, 1yq9:B
77 4pe5:D 727 55 0.0918 0.0248 0.3273 3.3 4pe5:B
78 8x0v:E 189 85 0.1224 0.1270 0.2824 3.7 8x0v:A, 8x0v:B, 8x0v:C, 8x0v:D, 8x0v:F, 8x0v:G, 8x0v:H, 8x0v:I, 8x0v:J, 8x0v:K, 8x0v:L
79 9are:B 789 55 0.0918 0.0228 0.3273 3.7 9are:D, 9arf:B, 9arf:D, 9ari:B, 9ari:D, 9bib:B, 9bib:D, 6e7r:B, 6e7r:D, 6e7s:B, 6e7s:D, 6e7t:B, 6e7t:D, 6e7u:B, 6e7u:D, 6e7v:B, 6e7v:D, 6e7w:B, 6e7w:D, 6e7x:B, 6e7x:D, 5ewj:B, 5ewj:D, 5ewl:B, 5ewl:D, 5ewm:B, 5ewm:D, 8g18:B, 8g18:D, 3jpy:A, 3qel:B, 3qel:D, 3qem:B, 3qem:D, 7saa:B, 7saa:D, 7sac:B, 7sac:D, 6whu:B, 6whu:D, 6whv:B, 6whv:D, 6whw:B, 6whw:D, 6whx:B, 6whx:D
80 5nm9:B 123 57 0.0867 0.1382 0.2982 6.0 5nm9:A
81 2d2m:D 145 120 0.1633 0.2207 0.2667 6.9 2d2n:D, 7e96:D, 7e97:D, 7e98:D, 7e99:D, 2zfo:D, 2zs0:D, 2zs1:D
82 6q8n:A 321 86 0.1071 0.0654 0.2442 8.3 6q8n:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218