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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEP
SVVAAASYASKIIKRAGGFTAQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQI
KGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTASCRIAFRYLSRQKDQGREIAE
KIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPV
ATKGGSIGLNPRVALSHDLLGNPSARELAQIIESIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAPLVE
RLISDKTFNLETAQRYLENLRS

The query sequence (length=422) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5wpk:B 422 422 1.0000 1.0000 1.0000 0.0 5wpj:A, 5wpk:A
2 7m1z:B 425 417 0.4408 0.4376 0.4460 1.09e-112 7m1z:A, 7m1z:C, 7m1z:D, 7m3h:A, 7m3h:B, 7m66:A, 7m66:C, 7m66:B, 7m66:D
3 1qax:A 425 400 0.3957 0.3929 0.4175 5.39e-100 8gdn:A, 8gdn:B, 4i4b:A, 4i4b:B, 4i56:A, 4i56:B, 4i6a:A, 4i6a:B, 4i6w:A, 4i6w:B, 4i6y:A, 4i6y:B, 1qax:B, 1qay:A, 1qay:B, 1r31:A, 1r31:B, 8sz6:A, 8sz6:B, 1t02:A, 8vlq:A, 8vlq:B
4 6dio:C 428 419 0.4005 0.3949 0.4033 3.51e-99 6dio:A, 6dio:B, 6eev:A
5 6p7k:A 375 366 0.3460 0.3893 0.3989 5.12e-83
6 3cd5:A 425 173 0.0972 0.0965 0.2370 2.35e-04 3bgl:A, 3bgl:B, 3bgl:C, 3bgl:D, 3cct:A, 3cct:B, 3cct:C, 3cct:D, 3ccw:A, 3ccw:B, 3ccw:C, 3ccw:D, 3ccz:A, 3ccz:B, 3ccz:C, 3ccz:D, 3cd0:A, 3cd0:B, 3cd0:C, 3cd0:D, 3cd5:B, 3cd5:C, 3cd5:D, 3cd7:A, 3cd7:B, 3cd7:C, 3cd7:D, 3cda:A, 3cda:B, 3cda:C, 3cda:D, 3cdb:A, 3cdb:B, 3cdb:C, 3cdb:D, 1dq8:A, 1dq8:B, 1dq8:C, 1dq8:D, 1dq9:A, 1dq9:B, 1dq9:C, 1dq9:D, 1dqa:A, 1dqa:B, 1dqa:C, 1dqa:D, 1hw8:A, 1hw8:B, 1hw8:C, 1hw8:D, 1hw9:A, 1hw9:B, 1hw9:C, 1hw9:D, 1hwi:A, 1hwi:B, 1hwi:C, 1hwi:D, 1hwj:A, 1hwj:B, 1hwj:C, 1hwj:D, 1hwk:A, 1hwk:B, 1hwk:C, 1hwk:D, 1hwl:A, 1hwl:B, 1hwl:C, 1hwl:D, 2q1l:A, 2q1l:B, 2q1l:C, 2q1l:D, 2q6b:A, 2q6b:B, 2q6b:C, 2q6b:D, 2q6c:A, 2q6c:B, 2q6c:C, 2q6c:D, 2r4f:A, 2r4f:B, 2r4f:C, 2r4f:D
7 8ecg:A 357 169 0.0995 0.1176 0.2485 3.10e-04
8 8tg9:A 426 36 0.0379 0.0376 0.4444 1.6 8tg9:B
9 5dnd:D 357 65 0.0616 0.0728 0.4000 2.5 5dnc:A, 5dnc:B, 5dnc:C, 5dnc:D, 5dnd:A, 5dnd:B, 5dnd:C, 5dne:A, 5dne:B, 5dne:C, 5dne:D, 4r8l:A, 4r8l:B, 4r8l:C, 4r8l:D
10 3odh:A 194 82 0.0521 0.1134 0.2683 5.9 3odh:B, 3odh:E, 3odh:F
11 9fcx:A 214 58 0.0498 0.0981 0.3621 6.7 9fcd:A, 9fcl:A, 9fcq:A, 9fcs:A, 9fcs:B, 9fcu:A, 9fcu:B, 9fcu:C, 9fcu:D, 9fcx:B, 9fcy:A, 9fcy:B, 9fcy:C, 9fcy:D, 9fd3:A, 9g0k:A, 9g0k:B
12 7usf:A 265 83 0.0592 0.0943 0.3012 9.1 5cz2:A, 5cz2:B, 5cz2:C, 5cz2:D, 5cz2:E, 5cz2:G, 5cz2:H, 5cz2:I, 5cz2:J, 5cz2:K, 5cz2:L, 3jca:A, 3jca:D, 3jca:E, 3jca:G, 3jca:C, 3jca:H, 3jca:B, 3jca:F, 7usf:B, 7ut1:a, 7ut1:d, 7ut1:e, 7ut1:A, 7ut1:D, 7ut1:E, 7ut1:C
13 7tm9:A 441 54 0.0403 0.0385 0.3148 9.4 7tm9:B, 7tm9:C, 7tm9:D, 7tm9:E, 7tm9:F, 7tm9:G, 7tm9:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218