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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ISVPQLDCPLSRPVHPEGERADAYAVEWLRGVGLMADEADAAPVLAVGLGRLAACYVDENASWDTLAFMTILLAWYAEYD
DRAIDSTDGLTDAEVAELHRALGEILRDRPAPDPSDPVQRGLADVWRTLNGLASDWDRAAFVDTTLRYFEANRYERVNIR
RGIPPTPSAHIGMRRHGGHVYGMYILGAAVNGYRPERRVLDHAAVRELETLAANYTSWANDLHSFAREHRMGQVNNLVWS
VHHHEGLTFQQAADRVADLCDKELAAYLELRQTLPELGIPLTGATGRHVRFLEDMMWSMVDWSARSAR

The query sequence (length=308) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8b4l:C 311 307 0.9968 0.9871 1.0000 0.0 8b4l:E, 8b4l:A, 8b4l:B, 8b4l:D, 8b4l:F, 8b4m:B, 8b4m:D, 8b4m:E, 8b4m:F
2 7zrn:A 301 307 0.2500 0.2558 0.2508 1.40e-18 7zrn:B
3 5dz2:A 322 327 0.2857 0.2733 0.2691 2.89e-18 5dz2:B
4 5nx5:A 287 269 0.2305 0.2474 0.2639 3.17e-14
5 4okm:A 346 311 0.2240 0.1994 0.2219 1.78e-12 4okm:B, 4okm:C, 4okz:A, 4okz:B, 4okz:C, 4okz:D
6 5nx7:A 308 311 0.2500 0.2500 0.2476 8.00e-11 5nx6:A, 5nx6:B, 5nx7:B
7 6oh6:A 311 143 0.1461 0.1447 0.3147 3.34e-09 6oh7:A
8 7ofl:A 335 168 0.1266 0.1164 0.2321 4.44e-09 7ofl:B
9 6wkd:A 280 228 0.1916 0.2107 0.2588 2.22e-08 6wkf:A, 6wkh:A
10 8h6u:A 338 200 0.1364 0.1243 0.2100 6.12e-08 8h6u:B, 8h6u:C, 8h6u:D
11 6wkj:A 251 134 0.1331 0.1633 0.3060 3.74e-06
12 6ax9:A 340 300 0.2468 0.2235 0.2533 4.05e-06 6axm:A, 6axn:A, 6axu:A, 3kb9:A, 7kj8:A, 7kj9:A, 7kjd:A, 7kje:A, 7kjf:A, 7kjg:A, 3lg5:A, 4ltz:A, 4luu:A, 4lxw:A, 4lz0:A, 4lz3:A, 4lzc:A, 6ofv:A, 8su1:A, 8su2:A, 8su3:A, 8su4:A, 8su5:A, 8v3k:A
13 8gr7:A 326 310 0.1981 0.1871 0.1968 8.72e-05 8gr7:B
14 4mc3:A 287 295 0.2240 0.2404 0.2339 0.30
15 5y4c:A 249 94 0.0714 0.0884 0.2340 0.91
16 5jb3:R 113 66 0.0682 0.1858 0.3182 1.1 5jbh:R, 6sw9:R, 6swc:R, 6swd:R, 4v4n:BR, 4v6u:AR, 7zag:R, 7zah:R, 7zai:R, 7zhg:R
17 7uus:R 170 50 0.0649 0.1176 0.4000 2.3 7utd:R, 7utd:S, 7utd:T, 7utd:Q, 7uus:Q, 7uus:T, 7uus:S
18 3e3u:A 196 69 0.0682 0.1071 0.3043 3.1
19 7pah:f 145 59 0.0487 0.1034 0.2542 7.0 7ood:f, 7p6z:f, 7pai:f, 7paj:f, 7pak:f, 7pal:f, 7pam:f, 7pan:f, 7pao:f, 7paq:f, 7par:f, 7pas:f, 7pat:f, 7pau:f, 7ph9:f, 7pha:f, 7phb:f, 7phc:f, 7pi8:f, 7pi9:f, 7pia:f, 7pib:f, 7pic:f, 7pio:f, 7pip:f, 7piq:f, 7pir:f, 7pis:f, 7pit:f
20 7dve:A 498 109 0.1104 0.0683 0.3119 7.5
21 4y28:G 91 51 0.0519 0.1758 0.3137 7.6
22 1ahp:A 796 29 0.0487 0.0188 0.5172 8.4 1ahp:B, 2asv:A, 2asv:B, 2av6:A, 2av6:B, 2aw3:A, 2aw3:B, 2azd:A, 2azd:B, 1e4o:A, 1e4o:B, 2ecp:A, 2ecp:B, 1l5v:A, 1l5v:B, 1l5w:A, 1l5w:B, 1l6i:A, 1l6i:B, 1qm5:A, 1qm5:B, 8rvk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218