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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ISLNQQRMNGVVAALKQSNARRVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIAQERLDRLRLPRNQWERLQLIQ
GALTYQDKRFHGYDAATVIEVIEHLDLSRLGAFERVLFEFAQPKIVIVTTPNIEYNVKFAHRFEWTRSQFQNWANKITER
FAYNVQFQPIGEADPEVGSPTQMAVFIHRGH

The query sequence (length=191) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3jwh:A 191 191 1.0000 1.0000 1.0000 4.19e-143 3jwh:B
2 3jwg:A 195 191 0.6283 0.6154 0.6283 9.66e-80
3 4xcx:A 216 196 0.3665 0.3241 0.3571 2.97e-36 5wy0:A
4 3htx:D 795 198 0.3560 0.0855 0.3434 1.26e-30 3htx:A
5 5f8f:B 361 80 0.1309 0.0693 0.3125 0.002 5f8e:A, 5f8e:B, 5f8f:A, 5f8f:C
6 4kdr:A 208 87 0.1152 0.1058 0.2529 0.006 5dpm:A
7 6bqc:A 348 65 0.0995 0.0546 0.2923 0.010
8 1nbh:A 292 65 0.1099 0.0719 0.3231 0.016 1d2h:A, 1d2h:B, 1d2h:C, 1d2h:D, 2idk:B, 2idk:C, 2idk:D, 2idk:A, 1kia:A, 1kia:B, 1kia:C, 1kia:D, 1nbh:B, 1nbh:C, 1nbh:D, 1nbi:A, 1nbi:B, 1nbi:C, 1nbi:D, 3thr:A, 3thr:B, 3thr:C, 3thr:D, 3ths:B, 3ths:C, 3ths:D, 3ths:A, 1xva:A, 1xva:B
9 6uak:A 297 72 0.1099 0.0707 0.2917 0.017
10 3ggd:A 243 40 0.0890 0.0700 0.4250 0.020
11 2p35:A 245 52 0.1099 0.0857 0.4038 0.021 2p35:B
12 5dm2:A 258 39 0.0681 0.0504 0.3333 0.032 5dm1:A, 5dm4:A, 4kwc:A
13 7pd7:B 250 42 0.0838 0.0640 0.3810 0.033 7pd7:A, 7pd7:C, 7pd7:D
14 4xru:C 424 179 0.2147 0.0967 0.2291 0.034 4xru:F
15 5u1e:A 321 39 0.0785 0.0467 0.3846 0.044 5tyq:A, 5u0n:A, 5u0t:A, 5u18:A, 5u19:A, 5u1i:A, 5u4t:A
16 5mgz:A 230 144 0.1832 0.1522 0.2431 0.062 5mgz:B
17 6uk5:A 240 52 0.0838 0.0667 0.3077 0.100 6uk5:B
18 5gm2:B 282 112 0.1832 0.1241 0.3125 0.10 5gm1:A, 5gm1:B, 5gm1:C, 5gm1:D, 5gm1:E, 5gm1:F, 5gm1:G, 5gm1:H, 5gm1:I, 5gm1:J, 5gm1:K, 5gm1:L, 5gm1:M, 5gm1:N, 5gm1:O, 5gm1:P, 5gm1:Q, 5gm1:R, 5gm2:A, 5gm2:C, 5gm2:D, 5gm2:E, 5gm2:F, 5gm2:G, 5gm2:H, 5gm2:I, 5gm2:J, 5gm2:L, 5gm2:M, 5gm2:N, 5gm2:O, 5gm2:P, 5gm2:Q, 5gm2:R
19 8xd5:A 419 87 0.1204 0.0549 0.2644 0.10 8hho:A, 8hiq:A, 8hiz:A, 8hj9:A, 8xco:A, 8xcp:A, 8xcq:A, 8xcr:A, 8xcs:A, 8xct:A, 8xcu:A, 8xcv:A, 8xcw:A, 8xcx:A, 8xcy:A, 8xcz:A, 8xd0:A, 8xd1:A, 8xd2:A, 8xd3:A, 8xd4:A, 8xd6:A, 8znb:A, 8znc:A, 8znd:A, 8zne:A, 8zng:A
20 6p3o:A 341 87 0.1257 0.0704 0.2759 0.12 6p3m:A, 6p3n:A
21 5epe:A 248 61 0.1047 0.0806 0.3279 0.12
22 5dm0:B 272 41 0.0838 0.0588 0.3902 0.12 5dly:A, 5dm0:A, 4kvz:A
23 7whs:A 366 42 0.0681 0.0355 0.3095 0.13 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
24 5bp7:A 249 61 0.0942 0.0723 0.2951 0.17 5bp7:B, 5bp7:C
25 5z9o:A 373 107 0.1152 0.0590 0.2056 0.17 5z9o:B
26 7zkh:A 266 50 0.0838 0.0602 0.3200 0.17 7zkg:A, 7zkg:B
27 7qw6:A 556 48 0.0942 0.0324 0.3750 0.22 7qw5:A, 7qw7:A
28 5gm2:K 267 109 0.1675 0.1199 0.2936 0.22
29 3anx:B 313 51 0.0785 0.0479 0.2941 0.24 3anx:A
30 6ecx:A 283 50 0.0785 0.0530 0.3000 0.25 6ect:A
31 6mro:A 194 41 0.0681 0.0670 0.3171 0.41 8gdu:A
32 1m6y:A 293 53 0.0838 0.0546 0.3019 0.47 1m6y:B, 1n2x:A, 1n2x:B
33 5wp5:A 463 57 0.0838 0.0346 0.2807 0.64 5wp5:B
34 4ine:A 431 111 0.1571 0.0696 0.2703 0.74 4ine:B
35 3n9m:A 503 43 0.0942 0.0358 0.4186 0.75 3n9l:A, 3n9m:C, 3n9n:A, 3n9o:A, 3n9p:A, 3n9q:A, 3puq:A, 3puq:C, 3pur:A, 3pur:C
36 5m58:A 230 146 0.1885 0.1565 0.2466 0.77 5m58:B
37 3e8s:A 220 40 0.0890 0.0773 0.4250 0.79
38 4lrs:A 337 107 0.1937 0.1098 0.3458 0.90 4lrt:A, 4lrt:C
39 8khq:A 700 40 0.0733 0.0200 0.3500 0.92 8khq:B, 8khq:C, 8khq:D
40 7smc:C 347 133 0.1571 0.0865 0.2256 1.0 7smc:A, 7smd:A, 7sme:A, 7smf:A, 7smf:C, 4yoo:A, 4yos:A, 4yoz:A
41 3i9f:B 169 44 0.0681 0.0769 0.2955 1.2 3i9f:A
42 1p91:A 268 58 0.0995 0.0709 0.3276 1.3 1p91:B
43 3e23:A 198 149 0.1728 0.1667 0.2215 1.3
44 3dtn:A 220 41 0.0838 0.0727 0.3902 1.4 3dtn:B
45 7wzg:B 243 55 0.0995 0.0782 0.3455 1.7 7wzg:A, 7wzg:C, 7wzg:D, 7wzg:E, 7wzg:F
46 6qmm:B 280 42 0.0733 0.0500 0.3333 1.7 6qmm:A
47 7asm:E 206 76 0.1099 0.1019 0.2763 1.8 7asn:E, 7aso:J, 7asp:E, 6ddd:S, 6ddg:S, 6fxc:AE, 6fxc:BE, 5hkv:C, 5hl7:C, 6hma:E, 5li0:F, 5nd8:F, 5nd9:F, 5ngm:AE, 7nhl:I, 7nhm:I, 5nrg:C, 8p2f:I, 8p2g:I, 8p2h:I, 7p48:E, 6s0x:E, 6s0z:E, 6s12:E, 6s13:E, 6sj6:F, 5t7v:LJ, 5tcu:LJ, 7ttu:S, 7ttw:S, 4wce:C, 4wf9:C, 4wfa:C, 4wfb:C, 6wqn:S, 6wqq:S, 6wrs:S, 6wru:S, 8y36:E, 8y37:E, 8y38:E, 8y39:E, 6yef:F
48 4pne:B 272 40 0.0785 0.0551 0.3750 1.9 4pne:A
49 8tjj:C 330 51 0.0785 0.0455 0.2941 2.0 8tjj:A, 8tjj:B, 8tjj:D, 8tjk:A, 8tjk:B
50 8owy:A 172 65 0.0995 0.1105 0.2923 2.2 8owy:B
51 3pij:B 526 72 0.0942 0.0342 0.2500 2.7 3pij:A
52 5je1:A 244 43 0.0681 0.0533 0.3023 2.7 5jdy:A, 5jdy:B, 5jdz:A, 5jdz:B, 5je0:A, 5je0:B, 5je1:B, 5je2:A, 5je2:B, 5je3:A, 5je3:B, 5je4:A, 5je4:B, 5je5:A
53 6gkv:A 351 87 0.1257 0.0684 0.2759 2.9 6gkv:B, 6gky:A, 6gky:B, 6gkz:A, 6gkz:B, 6gkz:C, 6gkz:D
54 7ezg:A 275 65 0.0995 0.0691 0.2923 3.0 7f1e:A, 7f1e:B, 8owx:A, 8owx:B, 8p7b:A, 8p7c:A, 8p7c:C, 8p7d:A
55 5kok:A 348 87 0.1047 0.0575 0.2299 3.1 5koc:A, 5koc:B, 5kok:B, 5kpc:A, 5kpc:B, 5kpg:A, 5kpg:B
56 7ebx:A 256 47 0.0628 0.0469 0.2553 3.6 7ec0:A, 7ec0:D, 7ec0:G, 7ec0:J, 7ec0:M
57 5tgq:A 226 20 0.0366 0.0310 0.3500 3.6 5tgx:A, 5tgx:B, 5tgx:C, 5tgx:D, 5th3:A, 5th3:B, 5th3:C, 5th3:D
58 6sg9:F4 541 41 0.0785 0.0277 0.3659 4.0 6sgb:F4
59 5fad:A 160 37 0.0681 0.0813 0.3514 4.1 5fa8:A
60 4nec:B 244 42 0.0681 0.0533 0.3095 4.3 4nec:A, 4nec:C, 4nec:D
61 2vz9:B 2086 41 0.0681 0.0062 0.3171 4.3 2vz9:A
62 6yb5:A 243 87 0.1257 0.0988 0.2759 4.3 6yar:A, 6yar:B, 6yay:A, 6yay:B, 6yb3:A, 6yb3:B, 6yb5:B, 6ybb:A, 6ybb:B, 6ybu:A, 6ybu:B, 6ybu:G, 6ybu:H
63 6c5b:A 332 36 0.0733 0.0422 0.3889 5.3 6c5b:B
64 4h03:A 414 134 0.1675 0.0773 0.2388 5.3 3buz:A, 1giq:A, 1giq:B, 1gir:A, 4h0t:A, 4h0v:A, 4h0x:A, 4h0y:A
65 7yf2:A 275 55 0.0890 0.0618 0.3091 6.5 8gze:B, 8gze:A, 8gzf:A, 8gzf:B, 7y9c:A, 7y9c:B, 7yf2:B, 7yf3:A, 7yf3:B, 7yf4:A, 7yf4:B
66 5e8j:A 310 50 0.0838 0.0516 0.3200 6.5 3bgv:A, 3bgv:B, 3bgv:C, 3bgv:D, 5e8j:B, 5e9j:A, 5e9j:B, 5e9w:A, 5e9w:B, 5e9w:C, 5e9w:D, 3epp:A, 3epp:B, 8q69:A, 8q69:B, 8q8g:A, 8q8g:B, 8q9w:A, 8q9w:B
67 7xif:D 288 88 0.1152 0.0764 0.2500 6.7 7xif:A, 7xif:B, 7xif:C, 7xif:E, 7xif:F, 7xif:G, 7xif:H, 7xif:I, 7xif:J, 7xif:K, 7xif:L, 7xig:A, 7xig:B, 7xig:C, 7xig:D, 7xig:E, 7xig:F, 7xig:G, 7xig:H, 7xih:A, 7xih:B, 7xii:A, 7xii:B, 7xii:C, 7xii:D
68 7uch:A 636 17 0.0471 0.0142 0.5294 6.8 6b39:A, 6b3a:A, 6b3b:A
69 7ux7:A 378 29 0.0628 0.0317 0.4138 7.7 7ux6:A, 7ux6:B, 7ux7:B, 7ux8:A, 7ux8:B
70 6s6q:A 833 72 0.0995 0.0228 0.2639 8.1 6s6q:B
71 6j28:A 345 116 0.1518 0.0841 0.2500 8.5 6j27:A, 6j27:B, 6j27:C, 6j27:D, 6j28:C, 6j28:B, 6j28:D
72 8bx8:C 3947 38 0.0681 0.0033 0.3421 8.7 7k58:C, 7k5b:C, 7kek:C
73 6uv6:C 264 51 0.0838 0.0606 0.3137 8.8 6uv6:A, 6uv6:B
74 8eg0:A 230 46 0.0785 0.0652 0.3261 8.9 3ckk:A, 8cth:A, 8cti:A, 8d59:A, 8d5b:A, 8d9l:A, 7ogj:A, 7ogj:B, 7pl1:A
75 7y3h:A 396 117 0.1466 0.0707 0.2393 9.1 8gx4:A, 8gzi:A
76 9enh:A 544 45 0.0785 0.0276 0.3333 9.6 9enh:B, 9enh:C, 9enh:D, 9eni:A, 9eni:B, 9eni:C, 9eni:D, 9enj:A, 9enj:B, 9enj:C, 9enj:D, 9enk:A, 9enk:B, 9enk:C, 9enk:D, 9enn:A, 9enn:B, 9enn:C, 9enn:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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