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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IRVKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYA
DYNNFYSLYLVKEELANSYVIDADNYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVS
FWDAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDYRKLEEILK

The query sequence (length=228) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1jyl:A 228 228 1.0000 1.0000 1.0000 1.48e-165 1jyl:B, 1jyl:C, 1jyl:D
2 7whs:A 366 97 0.1798 0.1120 0.4227 1.95e-16 7whs:B, 7whs:C, 7whs:D, 7whs:E, 7whs:F, 7wht:A, 7wht:B, 7wht:C, 7wht:D, 7wht:E, 7wht:F
3 7d72:K 360 122 0.1623 0.1028 0.3033 1.22e-13 7d72:I, 7d72:E, 7d72:F, 7d72:G, 7d72:H, 7d72:J, 7d72:L, 7d73:E, 7d73:F, 7d73:G, 7d73:I, 7d73:J, 7d73:K, 7d73:L, 7d73:H, 7d74:E, 7d74:F, 7d74:G, 7d74:H, 7d74:I, 7d74:J, 7d74:K, 7d74:L
4 4y7u:A 224 79 0.1491 0.1518 0.4304 3.07e-13 4y7v:A
5 2ggq:A 401 53 0.1404 0.0798 0.6038 5.31e-13 5z09:A, 5z09:B, 5z09:C, 5z09:D
6 7x8k:B 367 122 0.1711 0.1063 0.3197 3.13e-12 7x8k:A, 7x8k:D
7 6pd2:C 616 99 0.1316 0.0487 0.3030 6.68e-10 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
8 1mc3:A 291 123 0.1623 0.1271 0.3008 3.10e-09 1mc3:B
9 5i1f:A 290 61 0.1096 0.0862 0.4098 1.32e-08
10 5ve7:A 282 69 0.1184 0.0957 0.3913 7.52e-08
11 1wvc:A 254 54 0.1053 0.0945 0.4444 1.27e-07 1tzf:A
12 6jq8:A 225 52 0.0877 0.0889 0.3846 1.97e-07
13 3hl3:A 246 134 0.1711 0.1585 0.2910 2.47e-07 4ecm:A
14 8f73:E 281 64 0.1140 0.0925 0.4062 3.24e-07 8f73:A, 8f73:B, 8f73:C, 8f73:D, 8f73:F, 8f73:G, 8f73:H
15 1lvw:A 295 53 0.1053 0.0814 0.4528 3.37e-07 1lvw:B, 1lvw:C, 1lvw:D
16 6b5e:B 286 104 0.1491 0.1189 0.3269 3.52e-07 6b5e:A, 6b5e:C, 6b5e:D, 6b5e:E, 6b5e:F, 6b5e:G, 6b5e:H, 6b5k:A, 6b5k:B
17 2ux8:A 255 64 0.1096 0.0980 0.3906 5.37e-07 2ux8:H
18 5ify:A 293 51 0.1096 0.0853 0.4902 5.59e-07 5ify:B, 5ify:C, 5ify:D, 5ify:E, 5ify:F
19 4ho9:A 294 52 0.1096 0.0850 0.4808 6.10e-07 4ho3:A, 4ho4:A, 4ho5:A, 4ho5:B, 4ho6:A, 4ho8:A, 4ho8:B, 4ho8:C, 4ho8:D, 4ho9:B, 4hoc:A, 4hoc:B
20 2ux8:G 288 64 0.1096 0.0868 0.3906 7.27e-07 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F
21 6n0u:A 295 51 0.1096 0.0847 0.4902 7.86e-07 6n0u:B, 6n0u:C, 6n0u:D
22 3juk:A 265 67 0.1096 0.0943 0.3731 9.97e-07 3juk:B, 3juk:C, 3juk:D
23 1h5s:B 291 51 0.1096 0.0859 0.4902 1.78e-06 1h5r:A, 1h5r:B, 1h5r:C, 1h5r:D, 1h5s:A, 1h5s:D, 1h5s:C, 1h5t:A, 1h5t:D, 1h5t:B, 1h5t:C, 1iim:A, 1iim:B, 1iin:A, 1iin:B, 1iin:C, 1iin:D, 1mp3:A, 1mp3:B, 1mp4:A, 1mp4:B, 1mp5:A, 1mp5:B, 1mp5:C, 1mp5:D, 3pkp:A, 3pkp:B, 3pkp:C, 3pkp:D, 3pkp:I, 3pkp:J, 3pkp:K, 3pkp:L, 3pkq:A, 3pkq:B, 3pkq:C, 3pkq:D
24 4b2x:B 302 54 0.1096 0.0828 0.4630 2.36e-06 4arw:A, 4arw:B, 4arw:C, 4arw:D, 4asj:A, 4asj:B, 4asj:C, 4asj:D, 4asy:A, 4asy:B, 4asy:C, 4asy:D, 4b2w:A, 4b2w:B, 4b2w:C, 4b2w:D, 4b2x:A, 4b2x:C, 4b2x:D, 4b3u:A, 4b3u:B, 4b3u:C, 4b3u:D, 4b42:A, 4b42:B, 4b42:C, 4b42:D, 4b4b:A, 4b4b:B, 4b4b:C, 4b4b:D, 4b4g:A, 4b4g:B, 4b4g:C, 4b4g:D, 4b4m:A, 4b4m:B, 4b4m:C, 4b4m:D, 4b5b:A, 4b5b:B, 4b5b:C, 4b5b:D, 5fts:A, 5fts:B, 5fts:C, 5fts:D, 5ftv:A, 5ftv:B, 5ftv:C, 5ftv:D, 5fu0:A, 5fu0:B, 5fu0:C, 5fu0:D, 5fu8:A, 5fu8:B, 5fu8:C, 5fu8:D, 5fuh:A, 5fuh:B, 5fuh:C, 5fuh:D, 1fxo:A, 1fxo:C, 1fxo:B, 1fxo:D, 1fxo:E, 1fxo:H, 1fxo:F, 1fxo:G, 5fye:A, 5fye:B, 5fye:C, 5fye:D, 1g0r:A, 1g0r:B, 1g0r:C, 1g0r:D, 1g0r:E, 1g0r:G, 1g0r:H, 1g1l:A, 1g1l:C, 1g1l:B, 1g1l:D, 1g1l:E, 1g1l:H, 1g1l:F, 1g1l:G, 1g23:A, 1g23:B, 1g23:C, 1g23:D, 1g23:E, 1g23:F, 1g23:G, 1g23:H, 1g2v:A, 1g2v:C, 1g2v:B, 1g2v:D, 1g2v:E, 1g2v:G, 1g2v:F, 1g2v:H, 1g3l:A, 1g3l:C, 1g3l:B, 1g3l:D, 6t37:A, 6t37:B, 6t37:C, 6t37:D, 6t38:A, 6t38:B, 6t38:C, 6t38:D, 6tqg:A, 6tqg:B, 6tqg:C, 6tqg:D, 3zlk:A, 3zlk:B, 3zlk:C, 3zlk:D, 3zll:A, 3zll:B, 3zll:C, 3zll:D
25 6k8d:A 290 51 0.0965 0.0759 0.4314 3.12e-06 6ikz:B, 6k8d:B, 6k8d:C, 6k8d:D, 6knj:A, 6knj:B, 6knl:A, 6knl:B
26 7d72:A 407 115 0.1447 0.0811 0.2870 7.81e-06 7d72:B, 7d72:C, 7d72:D, 7d73:A, 7d73:B, 7d73:C, 7d73:D, 7d74:A, 7d74:D, 7d74:B, 7d74:C
27 6jlz:I 430 49 0.0833 0.0442 0.3878 2.59e-05
28 8b6d:A 291 58 0.0921 0.0722 0.3621 3.53e-05 8b68:A, 8b6d:B
29 4jd0:A 245 159 0.1886 0.1755 0.2704 3.75e-05
30 2xwl:B 222 50 0.0877 0.0901 0.4000 1.80e-04 2xwl:A, 2xwm:A, 2xwm:B
31 4mnd:A 408 119 0.1360 0.0760 0.2605 2.19e-04
32 1vpa:A 221 75 0.1096 0.1131 0.3333 3.73e-04 1vpa:B
33 6jly:E 414 57 0.0877 0.0483 0.3509 0.003 6jly:F, 6jlz:E, 6jlz:F
34 2pa4:B 299 49 0.0877 0.0669 0.4082 0.008 2pa4:A, 2pa4:C, 2pa4:D
35 4e1k:A 450 55 0.0833 0.0422 0.3455 0.018 4knr:A, 4knx:A, 4kpx:A, 4kpz:A, 4kql:A, 2v0i:A, 2v0j:A, 2v0k:A, 2v0l:A, 2vd4:A, 2w0v:A, 2w0w:A
36 3d8v:A 478 60 0.0658 0.0314 0.2500 0.071 3dj4:A, 4g3p:A, 4g3q:A, 4g3s:A, 4g87:A, 6ge9:A, 4hcq:A, 4k6r:A, 2qkx:A, 3spt:A, 3st8:A
37 3foq:A 439 60 0.0658 0.0342 0.2500 0.074
38 2x65:A 334 56 0.0921 0.0629 0.3750 0.082 2x5z:A, 2x5z:B, 2x60:A, 2x60:B, 2x65:B
39 1x3s:A 177 70 0.0877 0.1130 0.2857 0.17
40 4fce:A 441 55 0.0746 0.0385 0.3091 0.21
41 1xdq:C 264 78 0.1009 0.0871 0.2949 0.28 1xdq:A, 1xdq:B, 1xdq:D, 1xdq:E
42 6r8u:A 425 54 0.0833 0.0447 0.3519 0.38 5l6s:C, 5l6s:G, 5l6s:I, 5l6s:L, 5l6v:A, 5l6v:E, 5l6v:G, 5l6v:H, 5l6v:J, 5l6v:K, 5l6v:N, 5l6v:B, 5l6v:C, 5l6v:D, 5l6v:F, 5l6v:L, 5l6v:M, 5l6v:O, 5l6v:P, 6r8b:D, 6r8b:B, 6r8b:A, 6r8b:C, 6r8u:B, 6r8u:D, 6r8u:C, 6shj:D, 6shj:A, 6shj:B, 6shj:C, 6shn:D, 6shn:C, 6shq:A, 6shq:D, 6shq:C, 6shq:B, 6si8:A, 6si8:B, 6si8:D, 6si8:C
43 5l6v:I 400 54 0.0833 0.0475 0.3519 0.48
44 5lj3:C 882 118 0.1184 0.0306 0.2288 1.2 6exn:C, 5gam:C, 5gan:C, 5lj5:C, 5lqw:B, 5mps:C, 5mq0:C, 5nrl:C
45 3oaj:A 310 58 0.0833 0.0613 0.3276 1.4 3oaj:B
46 2oi6:B 452 62 0.0833 0.0420 0.3065 1.7 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
47 5ojg:A 260 76 0.1053 0.0923 0.3158 1.8 5ojg:B, 5oji:A, 5oji:B
48 1hm8:A 458 56 0.0789 0.0393 0.3214 2.7 4aaw:A, 4ac3:A, 1g97:A, 1hm8:B, 1hm9:A, 1hm9:B, 7kr9:A
49 2xwn:B 227 45 0.0789 0.0793 0.4000 3.2 3okr:D, 3q7u:A, 3q7u:B, 3q80:A, 3q80:B, 2xwn:A
50 3k8d:A 246 29 0.0526 0.0488 0.4138 3.9 3k8d:B, 3k8d:C, 3k8d:D
51 2z67:A 434 83 0.0921 0.0484 0.2530 5.8 2z67:B, 2z67:C, 2z67:D
52 3fwr:B 146 56 0.0570 0.0890 0.2321 7.2 3fwr:A, 3fws:A, 3fws:B
53 7oxy:A 473 51 0.0482 0.0233 0.2157 8.6 4b0s:A, 5lrt:A, 7oy3:A, 7oyf:A, 7oyh:A
54 5zw4:A 216 64 0.0833 0.0880 0.2969 8.9 5zw3:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218