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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IRSVTEEDYLKIIQELVLYKGYATLADISRSLNVKRQSVRDEINHLISLSMAEKIERGKYRLTPSGDREANRFLRKHRTA
EILLSRCIGIPWERVDEEAMGIEHGMTEEIIQRTIERFGVDRCPHGNPIPDPEGNVEPVADVRITSLLPDSTARISRIVY
ETDDILHFLALNGLIPGKDIKIESVKDTVRVLVDGRSIEIPTDIAMAIMVTVD

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4o5v:A 213 213 1.0000 1.0000 1.0000 1.76e-155 4o6j:A
2 3hru:A 211 213 0.2911 0.2938 0.2911 1.48e-15 3hru:B
3 8pw0:A 137 135 0.2066 0.3212 0.3259 8.15e-15
4 5zr6:A 214 214 0.2488 0.2477 0.2477 3.85e-14 5zr6:B
5 7b20:B 228 222 0.3192 0.2982 0.3063 1.02e-12 7b1v:A, 7b1v:B, 7b1y:A, 7b1y:B, 7b1y:C, 7b1y:D, 7b1y:dd, 7b1y:aa, 7b20:A, 7b20:C, 7b20:D, 7b20:dd, 7b20:aa, 7b23:A, 7b23:B, 7b23:C, 7b23:D, 7b23:dd, 7b23:aa, 7b24:A, 7b24:B, 7b24:C, 7b24:D, 7b24:dd, 7b24:aa, 7b25:A, 7b25:B, 7b25:C, 7b25:D, 7b25:dd, 7b25:aa
6 6o5c:A 215 213 0.2629 0.2605 0.2629 6.77e-12 6o5c:B
7 1fx7:A 230 221 0.2817 0.2609 0.2715 4.49e-11 1b1b:A, 1fx7:B, 1fx7:C, 1fx7:D, 2isz:A, 2isz:B, 2isz:C, 2isz:D, 2it0:A, 2it0:B, 2it0:C, 2it0:D, 1u8r:A, 1u8r:B, 1u8r:C, 1u8r:D, 1u8r:G, 1u8r:H, 1u8r:I, 1u8r:J
8 5cvi:B 215 212 0.2254 0.2233 0.2264 4.75e-11 5cvi:A
9 1c0w:D 175 115 0.1784 0.2171 0.3304 3.48e-10
10 1c0w:B 219 156 0.2254 0.2192 0.3077 8.63e-10 1bi0:A, 1bi3:A, 1bi3:B, 1c0w:A, 1c0w:C, 1ddn:A, 1ddn:B, 1ddn:C, 1ddn:D, 2dtr:A, 1f5t:A, 1f5t:B, 1f5t:C, 1f5t:D, 1fwz:A, 1g3w:A, 1g3y:A
11 2x4h:C 131 109 0.1690 0.2748 0.3303 4.02e-09 2x4h:A, 2x4h:B, 2x4h:D
12 9c4d:E 140 110 0.1737 0.2643 0.3364 5.95e-07 9c4c:E, 9c4c:F, 9c4c:G, 9c4c:H, 9c4d:F, 9c4d:G, 9c4d:I, 9c4d:D, 9c4d:H, 9c4d:J, 9c4d:C, 2ev0:A, 2ev0:B, 2ev5:A, 2ev5:B, 2ev6:A, 2ev6:B, 2f5c:A, 2f5d:A, 2f5d:B, 2f5e:A, 2f5e:B, 2f5f:A, 2f5f:B, 4hv5:A, 4hv5:B, 4hv6:A, 4hv6:B, 4hx4:A, 4hx4:B, 1on1:A, 1on1:B, 1on2:A, 1on2:B, 3r60:A, 3r60:B, 3r61:A, 3r61:B
13 6ktb:B 138 110 0.1643 0.2536 0.3182 6.42e-07
14 7ale:A 419 134 0.1737 0.0883 0.2761 1.2 7ale:B, 6yb8:A, 6yb8:B, 6yb9:A, 6yb9:B
15 6iy8:A 469 79 0.0986 0.0448 0.2658 3.1 6iy8:B, 6iy8:C, 6iy8:D
16 4hr3:A 407 41 0.0704 0.0369 0.3659 3.4
17 5wqo:A 234 28 0.0516 0.0470 0.3929 3.5 5wqp:A
18 5kay:A 201 38 0.0657 0.0697 0.3684 5.6 5kay:B
19 8h2w:B 984 43 0.0657 0.0142 0.3256 6.1 8h2w:A, 5nz8:B
20 5d1w:D 196 44 0.0516 0.0561 0.2500 7.4 5d1w:A, 5d1w:B, 5d1w:C
21 5t13:A 376 123 0.1221 0.0691 0.2114 7.6
22 7oya:T2 137 34 0.0657 0.1022 0.4118 9.4 7oyb:T2
23 3r7d:A 291 78 0.0939 0.0687 0.2564 9.6 3r7d:C, 3r7d:B, 3r7f:A, 3r7f:B, 3r7f:C, 3r7l:A, 3r7l:B, 3r7l:C, 3r7l:D, 3r7l:E, 3r7l:F
24 7pay:A 329 67 0.0845 0.0547 0.2687 9.7 7pax:A, 7pb0:A, 7pb1:A, 6w2l:A, 6z1n:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218