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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IRRIGKKKGATMKDVHPWRWVKLCSQHFKQEGKLMVPNCTEIVKSSHGRERAPQNPDWYYIRCAAILRAVYMRPGVGYGG
LSKRFSNKKNRGSRPEITVRASKGLLHWGCKSLTKLGLIEKCESSGHRITKNGRKLADAI

The query sequence (length=140) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ase:O 140 140 1.0000 1.0000 1.0000 1.16e-102 5opt:o
2 8ova:AO 154 140 0.8571 0.7792 0.8571 4.69e-91 8ove:AO, 4v8m:AO
3 6az1:X 152 140 0.7286 0.6711 0.7286 7.56e-77 8a3w:SX, 8a98:SX, 8ovj:SX, 8rxh:SX, 8rxx:SX, 5t2a:AO
4 5xxu:T 151 131 0.3857 0.3576 0.4122 4.06e-32
5 6zj3:SX 143 133 0.3500 0.3427 0.3684 1.76e-29
6 4v3p:SS 146 130 0.3500 0.3356 0.3769 6.65e-29 8ip8:ra, 8ip9:ra, 8ipa:ra, 8ipb:ra, 8jiw:BT, 8r57:T, 4v7e:BT
7 7qiy:K 140 130 0.3429 0.3429 0.3692 5.63e-28 8auv:E, 8b2l:E1, 7qiz:UA
8 7r81:U2 143 133 0.3714 0.3636 0.3910 1.62e-27
9 7olc:ST 142 133 0.3714 0.3662 0.3910 1.22e-25 7old:ST, 8oo0:ST, 6rxx:Cr, 7z3n:ST, 7z3o:ST
10 8c3a:V 141 133 0.3500 0.3475 0.3684 1.45e-25 8c3a:DG, 8cq7:V, 8cq7:DG, 8cqw:V, 8cqw:DG, 8cre:V, 8cre:DG, 8oeq:V, 8oeq:DG, 7pzy:U, 7q08:U, 7q0f:U, 7q0p:U, 7q0r:U, 8q5i:U
11 6fyx:T 143 133 0.3571 0.3497 0.3759 4.36e-25 6fyy:T, 6gsm:T, 6gsn:T, 8i7j:T, 5it7:T, 5it9:T, 3j80:T, 3j81:T, 3jam:T, 3jap:T, 8rw1:T, 8s8d:T, 8s8e:T, 8s8f:T, 8s8g:T, 8s8h:T, 8s8i:T, 8s8j:T, 6uz7:T
12 4v6i:AS 144 133 0.3357 0.3264 0.3534 5.44e-25 7a1g:J, 7aju:DT, 7b7d:I, 8bn3:C9, 8bqd:I, 8bqx:I, 8c00:I, 8c01:I, 8cah:J, 8cas:K, 8cbj:T, 8ccs:v, 8cdl:v, 8cdr:v, 8ceh:v, 8cf5:v, 8cg8:v, 8cgn:v, 8civ:v, 8cku:v, 8cmj:v, 7d4i:SU, 7d63:SU, 5dat:C9, 5dat:c9, 5dc3:C9, 5dc3:c9, 5dge:C9, 5dge:c9, 5dgf:C9, 5dgf:c9, 5dgv:C9, 5dgv:c9, 6eml:I, 8eub:BT, 8evp:BT, 8evq:BT, 8evr:BT, 8evs:BT, 8evt:BT, 8ewb:BT, 8ewc:BT, 6fai:T, 5fci:C9, 5fci:c9, 5fcj:C9, 5fcj:c9, 6gq1:AJ, 6gqb:AJ, 6gqv:AJ, 6hhq:U, 6hhq:c9, 5i4l:C9, 5i4l:c9, 6i7o:I, 6i7o:Ib, 3j6x:19, 3j6y:19, 3j77:19, 3j78:19, 5juo:QB, 5jup:QB, 5jus:QB, 5jut:QB, 5juu:QB, 8k2d:ST, 8k82:ST, 5lyb:C9, 5lyb:c9, 5m1j:T2, 5mc6:I, 5mei:c9, 5mei:U, 7mpi:BT, 7mpj:BT, 7n8b:BT, 5ndg:C9, 5ndg:c9, 5ndv:C9, 5ndv:c9, 5ndw:C9, 5ndw:c9, 7nrc:SI, 7nrd:SI, 5obm:C9, 5obm:c9, 5on6:c9, 5on6:U, 7osa:eS19, 7osm:eS19, 6q8y:I, 6rbd:T, 6rbe:T, 7rr5:ST, 6s47:BU, 6snt:T, 6sv4:I, 6sv4:Ib, 6sv4:Ic, 6t4q:ST, 6t7i:ST, 6t7t:ST, 6t83:Tb, 6t83:u, 5tbw:U, 5tbw:c9, 6tb3:I, 5tga:C9, 5tga:c9, 5tgm:C9, 5tgm:c9, 6tnu:I, 4u3m:C9, 4u3m:c9, 4u3n:C9, 4u3n:c9, 4u3u:C9, 4u3u:c9, 4u4n:C9, 4u4n:c9, 4u4o:C9, 4u4o:c9, 4u4q:C9, 4u4q:c9, 4u4r:C9, 4u4r:c9, 4u4u:C9, 4u4u:c9, 4u4y:C9, 4u4y:c9, 4u4z:C9, 4u4z:c9, 4u50:C9, 4u50:c9, 4u51:C9, 4u51:c9, 4u52:C9, 4u52:c9, 4u53:C9, 4u53:c9, 4u55:C9, 4u55:c9, 4u56:C9, 4u56:c9, 4u6f:C9, 4u6f:c9, 4uer:T, 4v7h:AT, 4v88:AT, 4v88:CT, 4v8y:AT, 4v8z:AT, 4v92:BT, 6wdr:T, 6woo:TT, 6xiq:AJ, 6xir:AJ, 8y0u:ST, 6y7c:T, 6z6j:ST, 6z6k:ST, 6zce:U, 7zpq:AT, 6zqd:DT, 6zqe:DT, 6zqf:DT, 6zqg:DT, 7zrs:AT, 6zu9:K, 7zuw:AT, 7zux:DT, 6zvi:B, 7zw0:sI
13 4v6w:AT 154 132 0.3286 0.2987 0.3485 1.93e-24 6xu6:AT, 6xu7:AT, 6xu8:AT
14 3j7a:Y 154 128 0.3286 0.2987 0.3594 8.74e-22 3jbn:Y, 3jbo:Y, 3jbp:Y, 6okk:Y, 8tpu:SY
15 5a2q:T 145 132 0.3000 0.2897 0.3182 1.52e-21 7a01:H5, 7a09:x, 5aj0:BT, 9bdl:AS19, 9bdn:AS19, 9bdp:AS19, 8bhf:U3, 9bkd:d, 9bln:d, 8btk:As, 7cpu:ST, 7cpv:ST, 4d5l:T, 4d61:T, 6d90:UU, 6d9j:UU, 9f1b:As, 9f1c:As, 9f1d:As, 6fec:R, 5flx:T, 6g18:T, 6g4s:T, 6g4w:T, 6g51:T, 6g53:T, 6g5h:T, 6g5i:T, 8g5y:ST, 8g5z:ST, 8g60:ST, 8g61:ST, 8g6j:ST, 8glp:ST, 6gz3:BT, 6gz4:BT, 6gz5:BT, 6hcf:U1, 6hcj:U2, 6hcm:U1, 6hcq:U2, 8ifd:20, 8ife:20, 6ip5:20, 6ip6:20, 6ip8:20, 3j7p:ST, 3j7r:ST, 3jag:TT, 3jah:TT, 3jai:TT, 3jaj:ST, 3jan:ST, 8jdj:AF, 8jdk:AF, 8jdl:AF, 8jdm:AF, 7jqb:U, 7jqc:U, 5k0y:R, 8k2c:ST, 7k5i:T, 4kzx:T, 4kzy:T, 4kzz:T, 5lks:ST, 7ls1:B3, 7ls2:B3, 5lzs:TT, 5lzt:TT, 5lzu:TT, 5lzv:TT, 5lzw:TT, 5lzx:TT, 5lzy:TT, 5lzz:TT, 7mdz:TT, 7mqa:NP, 6mtb:TT, 6mtc:TT, 6mtd:TT, 6mte:TT, 7nwg:U2, 7nwh:TT, 7nwi:TT, 7o7y:As, 7o7z:As, 7o80:As, 7o81:As, 5oa3:T, 6ole:ST, 6olf:ST, 6olg:BT, 6oli:ST, 6olz:BT, 6om0:ST, 6om7:ST, 7oyc:T2, 7oyd:TT, 8oz0:l, 8p03:V, 8p09:V, 8p2k:As, 6p4g:U, 6p4h:U, 6p5i:U, 6p5j:U, 6p5k:U, 6p5n:U, 8pj1:d, 8pj2:d, 8pj3:d, 8pj4:d, 8pj5:d, 8pj6:d, 8ppk:T, 8ppl:AT, 8q7z:As, 8q87:As, 7qgg:ST, 8qoi:ST, 7qp6:d, 7qp7:d, 7qvp:ST, 7qvp:RT, 6qzp:ST, 7r4x:T, 6r5q:PP, 6r6g:PP, 6r6p:PP, 6r7q:PP, 8scb:TT, 6sgc:U1, 7syg:U, 7syh:U, 7syi:U, 7syj:U, 7syk:U, 7syl:U, 7sym:U, 7syn:U, 7syo:U, 7syp:U, 7syq:U, 7syr:U, 7sys:U, 7syt:U, 7syu:U, 7syv:U, 7syw:U, 7syx:U, 5t2c:AU, 8t4s:T, 7toq:AS19, 7tor:AS19, 7tql:U, 7ucj:TT, 7uck:TT, 4ug0:ST, 4ujc:CT, 4ujd:CT, 4uje:BT, 4v6x:AT, 5vyc:T1, 5vyc:T2, 5vyc:T3, 5vyc:T4, 5vyc:T5, 5vyc:T6, 6w2s:U, 6w2t:U, 7wtt:T, 7wtu:T, 7wtv:T, 7wtw:T, 7wtx:T, 7wtz:T, 7wu0:T, 6xa1:ST, 7xnx:ST, 7xny:ST, 8xsx:ST, 8xsy:ST, 8xsz:ST, 8xxl:ST, 8xxm:ST, 8xxn:ST, 6y0g:ST, 8y0w:ST, 8y0x:ST, 6y2l:ST, 6y57:ST, 6yal:V, 6yam:V, 6yan:V, 6ybs:d, 8yoo:ST, 8yop:ST, 6z6l:ST, 6z6m:ST, 6z6n:ST, 7zjw:Se, 7zjx:Se, 6zlw:U, 6zm7:ST, 6zme:ST, 6zmi:ST, 6zmo:ST, 6zmt:U, 6zmw:d, 6zn5:U, 6zoj:T, 6zol:T, 6zon:x, 6zp4:x, 6zuo:T, 6zv6:T, 6zvh:T, 6zvj:x, 6zvk:H5, 6zxd:T, 6zxe:T, 6zxf:T, 6zxg:T, 6zxh:T
16 4bts:AT 154 128 0.3286 0.2987 0.3594 5.81e-21 4bts:BT, 4bts:CT, 4bts:DT, 4v5o:AT, 4v5o:BT
17 7oya:T2 137 129 0.3143 0.3212 0.3411 5.82e-21 7oyb:T2
18 6sw9:U 149 131 0.3143 0.2953 0.3359 5.97e-19 5jb3:U, 5jbh:U, 6swc:U, 6swe:U, 4v4n:BU, 4v6u:AU, 7zag:U, 7zah:U, 7zai:U, 7zhg:U
19 9bh5:AT 140 134 0.3071 0.3071 0.3209 1.35e-17 9cai:AT
20 6zu5:ST0 139 99 0.2643 0.2662 0.3737 4.01e-16
21 6skf:Av 149 131 0.2714 0.2550 0.2901 7.45e-16 6skg:Av, 6th6:Av, 6tmf:V
22 6rm3:ST0 131 122 0.2357 0.2519 0.2705 1.75e-14
23 5xyi:T 146 133 0.2429 0.2329 0.2556 2.76e-13
24 8bsi:SW 138 124 0.2571 0.2609 0.2903 5.08e-13 8br8:SW, 8brm:SW, 8bsj:SW, 8btd:SW, 8btr:SW, 8fvy:T, 8g4s:T, 7pwf:T, 7pwo:T1
25 7qep:C9 135 127 0.2571 0.2667 0.2835 1.34e-12
26 8p5d:ST0 142 110 0.2500 0.2465 0.3182 6.30e-12 8p60:ST0, 8p60:RT0, 7qca:ST0
27 8hkx:S19E 150 120 0.2571 0.2400 0.3000 3.46e-10 8hky:S19E, 8hkz:S19E, 8hl1:S19E, 8hl2:S19E, 8hl3:S19E, 8hl4:S19E, 8hl5:S19E, 8wkp:S19E, 8wq2:S19E, 8wq4:S19E
28 4v7r:AM 106 132 0.2357 0.3113 0.2500 3.41e-08 4v7r:CM
29 8s0l:A 369 47 0.1214 0.0461 0.3617 0.31 8hd8:A, 8hd8:C, 8hd8:B, 8hd8:D, 7meq:A, 8v04:B, 8v1f:C, 8v1f:B, 8v1f:D, 7xyd:A, 7xyd:C, 7xyd:B, 7xyd:D, 7y0e:A, 7y0e:C, 7y0e:B, 7y0e:D, 7y0f:A, 7y0f:C, 7y0f:B, 7y0f:D
30 6heg:A 783 58 0.1071 0.0192 0.2586 4.9
31 3qgu:A 406 81 0.1571 0.0542 0.2716 7.8
32 7ezx:MC 280 12 0.0500 0.0250 0.5833 8.7 7ezx:ME, 7y4l:ZG, 7y4l:MG, 7y5e:ZI, 7y5e:MI, 7y7a:MJ, 7y7a:Mk, 7y7a:ZJ, 7y7a:Zk
33 7oik:A 4426 60 0.1143 0.0036 0.2667 9.8 7oim:A, 6tax:A, 6tay:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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