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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IQTVVKRDGRIVGFNEQKIMAAIRKAMLHTDKDTTLIEQITDHISYMSVEAIQDAIEMELMKSDVAQKYIAYRNQRNIAR
KAKTRDVFMSIVNAKNNDITRENANMNADTPAGMMMKFASETTKPFVDDYLLSEDVRDAVMHNYIHIHDKDYYPTKSLTC
VQHPLDVILNHGFRPAKRIETAAVLACISLETCQNEMHGGQAIPAFDFYLAPYVRMSYQEEVKNLEKLTGEDLSNLYDAP
IDDYIEKPLDGLQGRERLEQHAINKTVNRVHQAMEAFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIMREILQSTYQ
GVGNGETAIFPIQIWKKKRGVNYLPEDRNYDLYKLACKVTARRFFPNFLNLDATFNQNEKWRADDPERYKWEIATMGCRT
RVFEDRWGEKTSIARGNLSFSTINIVKLAIECMGIENEKQRIDMFFAKLDNILDITAKQLDERFQFQKTAMAKQFPLLMK
YLWVGAENLKPEETIESVINHGTLGIGFIGLAECLVALIGKHHGESEKAQELGLKIITYMRDRANEFSEQYHHNYSILAT
PAEGLSGKFTKKDRKQFGVIPGVTDRDYYTNSNHVPVYYKCTALKKAQIEAPYHDLTRGGHIFYVEIDGDATHNPSVIES
VVDMMDKYNMGYGSVNHNRNRCGYENADAHLEVCPKCGSHHIDKLQRITGYLVGTTDRWNSGKLAELHDRVTHIG

The query sequence (length=715) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8p23:B 715 715 1.0000 1.0000 1.0000 0.0 8p23:A, 8p27:A, 8p27:B, 8p28:A, 8p28:B, 8p28:C, 8p28:D, 8p2c:A, 8p2c:B, 8p2c:C, 8p2c:D, 8p2d:A, 8p2d:B, 8p2s:A, 8p2s:B, 8p39:A, 8p39:B
2 1h7a:A 563 579 0.2294 0.2913 0.2832 1.53e-55 1h78:A, 1h79:A, 1h7b:A, 1hk8:A
3 4u3e:A 637 286 0.0881 0.0989 0.2203 1.24e-06 4coi:A, 4coi:B, 4coj:A, 4coj:B, 4col:A, 4col:B, 4com:A, 4com:B, 4u3e:B
4 5olk:A 395 114 0.0545 0.0987 0.3421 1.71e-05 5olk:B, 5olk:C, 5olk:D, 6sf5:A, 6sf5:B
5 5im3:A 874 100 0.0448 0.0366 0.3200 9.39e-05 5im3:B
6 6rxt:CT 131 38 0.0168 0.0916 0.3158 1.4 5oql:k, 6rxu:CT, 6rxv:CT, 6rxx:CT, 6rxy:CT, 6rxz:CT
7 7dh0:G 123 37 0.0182 0.1057 0.3514 2.2 7dkf:G2, 8ic2:Q, 8ic3:Q
8 4xx6:B 321 54 0.0294 0.0654 0.3889 4.6 4xx6:A
9 4qqq:A 483 37 0.0210 0.0311 0.4054 8.6
10 6noz:A 248 125 0.0420 0.1210 0.2400 9.6 7f0u:A, 7f0u:B, 7mc9:A, 7mc9:C, 7mc9:E, 7mc9:G, 7mc9:I, 7mc9:K, 7mc9:M, 7mc9:O

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218