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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IPHTHAHLVDAFQALGIRAGQALMLHASVKAVGAVMGGPNVILQALMDALTPDGTLMMYAGWQDIPDFIDSLPDALKAVY
LEQHPPFDPATARAVRENSVLAEFLRTWPCVHRSANPEASMVAVGRQAALLTANHALDYGYGVESPLAKLVAIEGYVLML
GAPLDTITLLHHAEYLAKMRHKNVVRYPCPILRDGRKVWVTVEDYDTGDPHDDYSFEQIARDYVAQGGGTRGKVGDADAY
LFAAQDLTRFAVQWLESRFG

The query sequence (length=260) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7q1d:D 272 260 1.0000 0.9559 1.0000 0.0 7mqk:A, 7mqk:B, 7mqk:C, 7mqk:D, 7mql:A, 7mql:B, 7mql:C, 7mql:D, 7mqm:A, 7mqm:B, 7mqm:C, 7mqm:D, 7q0q:A, 7q0q:B, 7q10:A, 7q1d:A, 7q1d:B, 7q1d:C, 7q1x:A
2 5ht0:C 261 260 0.4731 0.4713 0.4731 5.96e-76 5ht0:A, 5ht0:B, 5ht0:D, 5ht0:E, 5ht0:F, 7kes:A, 7kes:B, 6mn0:A, 6mn0:B, 6mn0:C, 6mn0:F, 6mn0:D, 6mn0:E, 6mn1:A, 6mn1:B, 6mn2:A, 6mn2:B
3 6mb6:A 268 250 0.4538 0.4403 0.4720 1.16e-68 6mb4:B, 6mb5:A, 6mb6:C, 6mb7:A, 6mb9:A, 6mb9:B, 6mb9:D, 6mb9:C
4 6bc2:A 268 264 0.3885 0.3769 0.3826 1.03e-59 6bbz:A, 6bc3:A, 6bc4:A, 6bc5:A, 6bc7:A, 6np2:A, 6np3:A, 6np4:A, 6np5:A, 6nti:A, 6ntj:A, 6o5u:A
5 2nyg:A 270 259 0.2923 0.2815 0.2934 5.77e-41 2nyg:B, 2nyg:C, 2nyg:D, 2nyg:E
6 3kzl:A 266 259 0.2808 0.2744 0.2819 5.94e-37 3ijw:A, 3ijw:B, 3kzl:D, 3kzl:C, 3kzl:B, 3n0m:A, 3n0m:B, 3n0s:A, 3n0s:D, 3n0s:C, 3n0s:B, 3slb:A, 3slb:D, 3slb:C, 3slb:B, 3slf:A, 3slf:B
7 3sma:B 268 257 0.3115 0.3022 0.3152 6.90e-30 3sma:A, 3sma:C, 3sma:D
8 6mn5:D 260 250 0.3038 0.3038 0.3160 1.07e-18 6mn3:A, 6mn3:B, 6mn4:A, 6mn4:B, 6mn4:C, 6mn4:D, 6mn4:E, 6mn4:F, 6mn5:A, 6mn5:B, 6mn5:C, 6mn5:E, 6mn5:F
9 4y5q:A 449 49 0.0615 0.0356 0.3265 2.1 9d8s:A, 3igo:A, 3mwu:A, 3ncg:A, 2wei:A
10 5wmm:A 870 62 0.0769 0.0230 0.3226 3.4
11 8w9z:G 218 78 0.0962 0.1147 0.3205 7.6 8wa0:G, 8wa1:G
12 8pqi:A 299 104 0.0923 0.0803 0.2308 7.8 6joi:A
13 7vtp:A 795 71 0.0769 0.0252 0.2817 9.8 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
14 6npy:A 798 71 0.0769 0.0251 0.2817 9.8
15 8ej4:A 850 71 0.0769 0.0235 0.2817 9.8 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
16 7pzc:A 1010 71 0.0769 0.0198 0.2817 10.0 7pzc:B, 7pzc:C, 7pzc:D, 7pzc:E, 7pzc:F, 7pzc:G, 7pzc:H, 7pzc:I, 7pzc:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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