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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
INFFEIYNSLPTLEEKKAFESALNIFNQDRQKVLENRATEAARERWKHDFEEAKARGDISIEKNLNVKLWKWYNEMLPLV
KEEINHCRSLLSEKLSDKKGLNKVDTNRLGYGPYLTLIDPGKMCVITILELLKLNSTGGVIEGMRTARAVISVGKAIEME
FRSEQVLKKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVTKAKVHGEAPAFAHGYQYHNGSKLGVLKIHKTLIRQLN
GERLIASVQPQLLPMLVEPKPWVNWRSGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTVNRKV
FDVVSQVWNKGEGFLDIPGAQDEMVLPPAPPKNSDPSILRAWKLQVKTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYF
PHNLDFRGRAYPLSPHFNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLPLKDRVAFTESHLQDIKDSAEN
PLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEFISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYA
HVARLVQKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQLSPIFDDRKESLDFSKYLTKHVFS
AIRELFHSAHLIQDWLGESAKRISKSIRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQTVFIS
DPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFASVHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLR
LKEEFDQRYKNYVKIGKLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIEDRNVGEKMVTTVSLF
EDITDLDALELSGMSVLLPLRLPEIPPKGDFDVTVLRNSQYFFS

The query sequence (length=924) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8c5s:A 924 924 1.0000 1.0000 1.0000 0.0 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
2 6ymv:A 887 933 0.9502 0.9899 0.9411 0.0
3 9bdc:E 990 662 0.2857 0.2667 0.3988 1.27e-154 9bdd:E, 4boc:A, 5ola:E, 5ola:F, 8u8u:E, 8u8v:E
4 6erp:A 1011 658 0.2879 0.2631 0.4043 3.72e-153 6erp:B, 6erq:A, 6erq:B
5 3spa:A 941 657 0.2760 0.2710 0.3881 3.51e-145 7a8p:A
6 8dh5:M 740 593 0.2002 0.2500 0.3120 1.13e-73
7 8dh4:I 821 832 0.2554 0.2875 0.2837 7.85e-73 8dh0:J
8 1msw:D 863 861 0.2630 0.2816 0.2822 5.11e-72 1cez:A, 8dh1:B, 8dh2:B, 8dh3:B, 8dh4:B, 8dh5:B, 3e2e:A, 3e3j:C, 3e3j:B, 1h38:A, 1h38:B, 1h38:C, 1h38:D, 2pi4:A, 2pi5:A, 1qln:A, 1s0v:A, 1s0v:B, 1s0v:C, 1s0v:D
9 8dh2:L 741 688 0.2197 0.2740 0.2951 7.11e-72
10 8dh3:M 775 708 0.2208 0.2632 0.2881 3.36e-71 8dh0:N
11 8dh1:L 702 707 0.2186 0.2877 0.2857 3.40e-71
12 8dh3:E 825 611 0.2024 0.2267 0.3061 8.99e-71 8dh4:M, 8dh5:E
13 8dh2:E 841 854 0.2587 0.2842 0.2799 2.18e-69 8dh0:B, 8dh1:E, 8dh1:I, 8dh2:I, 8dh3:I, 8dh4:E, 8dh5:I, 1s76:D, 1s77:D
14 8dh0:F 796 751 0.2359 0.2739 0.2903 2.75e-67
15 6dt7:B 404 170 0.0509 0.1163 0.2765 4.35e-04 6dt8:B, 6dta:B
16 6dt7:A 265 180 0.0465 0.1623 0.2389 0.029 6dt8:A, 6dta:A
17 2k6z:A 120 60 0.0206 0.1583 0.3167 0.32 2k70:A
18 8g9t:K 582 130 0.0335 0.0533 0.2385 1.7 8g9s:K, 8g9u:H, 8g9u:I, 8g9u:G, 8g9u:J, 8gam:H, 8gan:H, 8gan:G, 8gan:I, 8gan:J
19 6s6b:K 1024 112 0.0271 0.0244 0.2232 4.3 6s8b:K, 6s8e:K, 6s91:K, 6sh8:K, 6shb:K, 6sic:K
20 6wg0:H 223 96 0.0292 0.1211 0.2812 4.9
21 5jvj:B 797 133 0.0379 0.0439 0.2632 5.1
22 4dch:A 434 60 0.0206 0.0438 0.3167 5.6 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
23 5zia:G 220 97 0.0303 0.1273 0.2887 5.7 5zia:A, 5zia:D, 5zia:H, 5zia:K, 5zia:O
24 3idh:A 453 48 0.0173 0.0353 0.3333 6.2 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
25 5jvl:A 874 133 0.0379 0.0400 0.2632 6.3 5jvj:A, 5jvl:C, 5jvl:D, 5jvn:A
26 5lu4:A 850 122 0.0357 0.0388 0.2705 6.6 5lu4:B
27 7epu:B 748 80 0.0227 0.0281 0.2625 6.6 8b0a:K, 7enn:K, 7otq:K
28 8c07:B 450 40 0.0152 0.0311 0.3500 7.5
29 8ewg:A 1017 41 0.0141 0.0128 0.3171 8.1
30 7ugh:A 436 41 0.0141 0.0298 0.3171 8.6 7ugh:B
31 2doq:B 149 78 0.0206 0.1275 0.2436 9.8 2doq:A, 2doq:C, 4mbe:D, 4mbe:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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