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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANL
PSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNEQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINH
IRQGEVARTWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSK
TLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQH
YVIANLIRGGVFGE

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7elm:E 337 334 1.0000 0.9911 1.0000 0.0 6b44:D, 6b44:E, 6b44:F, 6b44:G, 6b44:H, 6b45:D, 6b45:E, 6b45:F, 6b45:G, 6b45:H, 6b46:D, 6b46:E, 6b46:F, 6b46:G, 6b46:H, 6b47:D, 6b47:E, 6b47:F, 6b47:G, 6b47:H, 6b48:D, 6b48:E, 6b48:F, 6b48:G, 6b48:H, 7ecv:D, 7ecv:E, 7ecv:F, 7ecv:G, 7ecv:H, 7ecw:D, 7ecw:E, 7ecw:F, 7ecw:G, 7ecw:H, 7elm:D, 7elm:F, 7elm:G, 7elm:H, 7elm:N, 7elm:O, 7elm:P, 7elm:Q, 7elm:R, 7eln:D, 7eln:E, 7eln:F, 7eln:G, 7eln:H, 7eln:N, 7eln:O, 7eln:P, 7eln:Q, 7eln:R, 7eqg:E, 7eqg:F, 7eqg:G, 7eqg:H, 7eqg:I, 7jzw:E, 7jzw:F, 7jzw:G, 7jzw:H, 7jzw:I, 7jzx:E, 7jzx:F, 7jzx:G, 7jzx:H, 7jzx:I, 7jzy:E, 7jzy:F, 7jzy:G, 7jzy:H, 7jzy:I, 7jzz:E, 7jzz:F, 7jzz:G, 7jzz:H, 7jzz:I, 6ne0:D, 6ne0:E, 6ne0:F, 6ne0:G, 6ne0:H, 7t3j:E, 7t3j:F, 7t3j:G, 7t3j:H, 7t3j:I, 7t3k:E, 7t3k:F, 7t3k:G, 7t3k:H, 7t3k:I, 7t3k:e, 7t3k:f, 7t3k:g, 7t3k:h, 7t3k:i, 7t3l:E, 7t3l:F, 7t3l:G, 7t3l:H, 7t3l:I, 7t3l:e, 7t3l:f, 7t3l:g, 7t3l:h, 7t3l:i, 7taw:E, 7taw:F, 7taw:G, 7taw:H, 7taw:I, 7taw:e, 7taw:f, 7taw:g, 7taw:h, 7taw:i, 7tax:E, 7tax:F, 7tax:G, 7tax:H, 7tax:I, 5uz9:D, 5uz9:E, 5uz9:F, 5uz9:G, 5uz9:H, 6vqv:F, 6vqv:G, 6vqv:H, 6vqv:I, 6vqv:J, 6vqw:E, 6vqw:F, 6vqw:G, 6vqw:H, 6vqw:I, 6vqx:E, 6vqx:F, 6vqx:G, 6vqx:H, 6vqx:I, 6w1x:D, 6w1x:E, 6w1x:F, 6w1x:G, 6w1x:H, 7we6:D, 7we6:E, 7we6:F, 7we6:G, 7we6:H, 7we6:N, 7we6:O, 7we6:P, 7we6:Q, 7we6:R, 6whi:D, 6whi:E, 6whi:F, 6whi:G, 6whi:H, 5xlo:B, 5xlo:C, 5xlo:D, 5xlo:E, 5xlo:F, 5xlp:D, 5xlp:E, 5xlp:F, 7yhs:D, 7yhs:F, 7yhs:G, 7yhs:H, 7yhs:I
2 7eqg:D 309 333 0.9192 0.9935 0.9219 0.0 6b44:C, 6b45:C, 6b46:C, 6b47:C, 6b48:C, 7ecv:C, 7ecw:C, 7elm:C, 7elm:M, 7eln:C, 7eln:M, 7jzw:D, 7jzx:D, 7jzy:D, 7jzz:D, 6ne0:C, 7t3j:D, 7t3k:D, 7t3k:d, 7t3l:D, 7t3l:d, 7taw:D, 7taw:d, 7tax:D, 5uz9:C, 6vqw:D, 6vqx:D, 6w1x:C, 7we6:C, 7we6:M, 6whi:C, 5xlo:A, 5xlp:C, 7yhs:C
3 6vqv:E 285 333 0.8443 0.9895 0.8468 0.0
4 8k0k:C 304 332 0.4102 0.4507 0.4127 6.50e-70 8k0k:D, 8k0k:E, 8k0k:F, 8k0k:G, 8k0k:H, 8k22:G, 8k22:I, 8k22:J, 8k22:K, 8k22:L, 8k22:M, 8k23:G, 8k23:I, 8k23:J, 8k23:K, 8k23:L, 8k23:M, 8k23:g, 8k23:i, 8k23:j, 8k23:k, 8k23:l, 8k23:m, 8k24:g, 8k24:i, 8k24:j, 8k24:k, 8k24:l, 8k24:m, 8k24:G, 8k24:I, 8k24:J, 8k24:K, 8k24:L, 8k24:M, 8k27:D, 8k27:C, 8k27:G, 8k27:F, 8k27:E, 8k27:H, 8k28:C, 8k28:D, 8k28:E, 8k28:F, 8k28:G, 8k28:H, 8k29:C, 8k29:D, 8k29:E, 8k29:F, 8k29:G, 8k29:H, 7wwu:C, 7wwu:D, 7wwu:E, 7wwu:F, 7wwu:G, 7wwu:H, 7wwv:C, 7wwv:D, 7wwv:E, 7wwv:F, 7wwv:G, 7wwv:H
5 8w1p:A 325 330 0.3743 0.3846 0.3788 6.04e-64 8w1p:B, 8w1p:C, 8w1p:D, 8w1p:E, 8ydb:I, 8ydb:H, 8ydb:G, 8ydb:F, 8ydb:E, 8yeo:I, 8yeo:E, 8yeo:F, 8yeo:G, 8yeo:H, 8yh9:H, 8yh9:G, 8yh9:E, 8yh9:D
6 8yh9:I 302 266 0.3323 0.3675 0.4173 3.15e-60 8w1p:F, 8ydb:D, 8yeo:D, 8yh9:F
7 6pij:A 351 353 0.2605 0.2479 0.2465 1.82e-25 8fuk:A, 8fuk:B, 8fuk:C, 8fuk:D, 8fuk:E, 6lnb:G, 6lnb:F, 6lnb:E, 6lnb:D, 6lnb:C, 6lnc:G, 6lnc:F, 6lnc:E, 6lnc:D, 6lnc:C, 6pif:A, 6pif:B, 6pif:C, 6pif:D, 6pif:E, 6pig:A, 6pig:B, 6pig:C, 6pig:D, 6pig:E, 6pij:B, 6pij:C, 6pij:D, 6pij:E, 6uvn:G, 6uvn:F, 6uvn:E, 6uvn:H, 6uvn:D, 6v9q:B, 6v9q:C, 6v9q:D, 6v9q:E, 6v9q:F, 6vbw:B, 6vbw:C, 6vbw:D, 6vbw:F, 6vbw:E
8 6pif:F 310 349 0.2515 0.2710 0.2407 5.58e-25 8fuk:F, 6lnb:B, 6lnc:B, 6pig:F, 6pij:F, 6uvn:C, 6v9q:G, 6vbw:G
9 7u5d:B 342 283 0.2545 0.2485 0.3004 9.61e-25 7u5d:C, 7u5d:D, 7u5d:E, 7u5d:F, 7u5e:B, 7u5e:C, 7u5e:D, 7u5e:E, 7u5e:F
10 7u5d:G 300 276 0.2455 0.2733 0.2971 8.90e-24 7u5e:G
11 5hy5:A 511 146 0.1198 0.0783 0.2740 0.29 5hy5:B
12 5x4z:C 265 34 0.0419 0.0528 0.4118 1.2 6a5l:C, 6a5o:C, 6a5p:C, 6a5r:C, 6a5t:C, 6a5u:C, 8h0v:C, 8h0w:C, 8he5:C, 6inq:C, 8jh2:C, 8jh3:C, 8jh4:C, 7wbv:C, 7wbw:C, 7wbx:C, 5x4z:O, 5x50:C, 5x51:C, 5x51:O, 7xn7:C, 5xog:C, 5xon:C, 7xse:C, 7xsx:C, 7xsz:C, 7xt7:C, 7xtd:C, 7xti:C, 8yfq:C, 8yfr:C
13 2v64:A 210 41 0.0359 0.0571 0.2927 3.9 6f0x:Z, 1klq:A, 2qyf:A, 2qyf:C, 2v64:F, 2v64:C
14 3b4x:A 367 83 0.0719 0.0654 0.2892 4.9 1ue8:A
15 4up7:A 529 102 0.0808 0.0510 0.2647 6.1 4up9:A, 4upa:A
16 3h0g:C 263 34 0.0419 0.0532 0.4118 6.4 3h0g:O
17 3gtg:C 271 28 0.0299 0.0369 0.3571 6.4 4a3b:C, 4a3c:C, 4a3d:C, 4a3e:C, 4a3f:C, 4a3g:C, 4a3i:C, 4a3j:C, 4a3k:C, 4a3l:C, 4a3m:C, 4a93:C, 2b63:C, 2b8k:C, 4bbr:C, 4bbs:C, 6blo:C, 6blp:C, 6bm2:C, 6bm4:C, 6bqf:C, 4bxx:C, 4bxz:C, 4by1:C, 4by7:C, 5c3e:C, 5c4a:C, 5c4j:C, 5c4x:C, 8cen:C, 8ceo:C, 3cqz:C, 2e2h:C, 2e2i:C, 2e2j:C, 3fki:C, 5fmf:C, 5fyw:C, 5fz5:C, 3gtj:C, 3gtk:C, 3gtl:C, 3gtm:C, 3gto:C, 3gtp:C, 3gtq:C, 6gyk:C, 6gyl:C, 6gym:C, 3h3v:D, 3hou:C, 3hou:O, 3hov:C, 3how:C, 3hox:C, 3hoy:C, 3hoz:C, 1i3q:C, 3i4m:C, 3i4n:C, 1i50:C, 1i6h:C, 6i84:C, 5ip7:C, 5ip9:C, 3j0k:C, 2ja5:C, 2ja6:C, 2ja7:C, 2ja7:O, 2ja8:C, 9ja1:C, 8jch:C, 3k1f:C, 8k5p:C, 3k7a:C, 1k83:C, 7ked:C, 7kee:C, 7kef:C, 3m3y:C, 3m4o:C, 7mei:c, 7mei:C, 7mk9:C, 7mka:c, 7ml0:C, 7ml1:C, 7ml2:C, 7ml4:C, 1nik:C, 7nkx:C, 2nvq:C, 2nvt:C, 2nvx:C, 2nvy:C, 2nvz:C, 7o4i:C, 7o4j:C, 6o6c:C, 7o72:C, 7o73:C, 7o75:C, 5oqj:C, 5oqm:C, 5ot2:C, 3po2:C, 3po3:C, 3qt1:C, 1r5u:C, 2r7z:C, 1r9s:C, 1r9t:C, 2r92:C, 2r93:C, 7rim:C, 7rip:C, 7riq:C, 7riw:C, 7rix:C, 7riy:C, 3rzd:C, 3rzo:C, 3s14:C, 3s15:C, 3s16:C, 3s17:C, 3s1m:C, 3s1n:C, 3s1q:C, 3s1r:C, 3s2d:C, 3s2h:C, 1sfo:C, 5sva:C, 8tug:C, 8tvp:C, 8tvq:C, 8tvs:C, 8tvv:C, 8tvw:C, 8tvx:C, 8tvy:C, 1twa:C, 1twc:C, 1twf:C, 1twg:C, 1twh:C, 5u5q:C, 8u9r:C, 8u9x:C, 8ukq:C, 8ukr:C, 8uks:C, 8ukt:C, 8uku:C, 6upx:C, 6upy:C, 6upz:C, 6uq0:C, 6uq1:C, 6uq2:C, 6uq3:C, 4v1m:C, 4v1n:C, 4v1o:C, 2vum:C, 5vvr:C, 5vvs:C, 5w4u:C, 5w51:C, 1wcm:C, 4x67:C, 4x6a:C, 1y1v:C, 1y1w:C, 4y52:C, 1y77:C, 4y7n:C, 2yu9:C, 7zs9:C, 7zsa:C, 7zsb:C
18 6or5:A 2058 156 0.1018 0.0165 0.2179 6.8
19 6rie:A 1285 55 0.0539 0.0140 0.3273 7.8 7amv:A, 7aof:A, 7aoh:A, 7aoz:A, 7ap8:A, 7ap9:A, 8c8h:A, 8p0j:A, 8p0k:A, 8p0n:A, 6rfl:A, 6ric:A, 6rid:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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