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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IKLQVKAGQANPSPPVGPALGQHGVNIMEFCKAFNAKTQGQEPGLPTPVIITVYSDRSFTFETKSTPAAVLLKKAAGITS
GSARPNSQKVGTVTRAQLEEIAKTKQADLTAADLDAAVRTIAGSARSMGLNVEG

The query sequence (length=134) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6spb:I 140 134 1.0000 0.9571 1.0000 9.20e-96 6spd:I, 6spf:I, 6spg:I, 7unr:J, 7unu:J, 7unv:J, 7unw:J
2 5ady:I 141 133 0.7313 0.6950 0.7368 6.54e-69 7abz:I, 5afi:I, 5aka:I, 7bl2:I, 7bl3:I, 7bl5:I, 6bu8:11, 7bv8:J, 6by1:CI, 6by1:DI, 6c4i:J, 7cpj:I, 4csu:I, 7d6z:I, 7d80:h, 3deg:H, 6dnc:M, 8fiz:BL, 8fzd:J, 8fze:J, 8fzf:J, 8fzg:J, 8fzh:J, 8fzi:J, 8fzj:J, 8g7p:J, 8g7q:J, 5gad:J, 5gae:J, 5gaf:J, 5gag:J, 5gah:J, 6gwt:I, 6gxm:I, 6gxn:I, 6gxo:I, 6gxp:I, 5h5u:J, 6hrm:I, 6i0y:I, 6i7v:DJ, 6i7v:CJ, 5iqr:I, 5it8:CJ, 5it8:DJ, 3j0d:G, 2j28:I, 3j5l:I, 5j5b:CJ, 5j5b:DJ, 3j7z:I, 5j7l:CJ, 5j7l:DJ, 3j8g:I, 5j88:CJ, 5j88:DJ, 5j8a:CJ, 5j8a:DJ, 3j9y:I, 3j9z:LE, 5j91:CJ, 5j91:DJ, 3ja1:LK, 3jbv:i, 3jcd:I, 3jce:I, 3jcj:H, 3jcn:I, 5jc9:CJ, 5jc9:DJ, 7jsz:i, 5jte:BI, 7jt3:i, 5ju8:BI, 7k50:i, 7k51:i, 7k52:i, 7k53:i, 7k54:i, 7k55:i, 5kcr:1K, 5kcs:1K, 5kps:I, 5kpv:H, 5kpw:H, 5kpx:H, 5l3p:K, 6lkq:Z, 7lv0:i, 5lza:I, 5lzb:I, 5lzc:I, 5lzd:I, 5lze:I, 5lzf:I, 7m5d:I, 5mdv:I, 5mdw:I, 5mdy:I, 5mdz:I, 7n1p:LK, 7n2c:LK, 7n2v:LK, 5nco:J, 5np6:g, 5nwy:V, 7nwt:I, 5o2r:I, 6o9j:6, 6o9k:I, 7oj0:9, 8p16:I, 8p17:I, 8p18:I, 8peg:k, 8phj:6, 6pj6:Q, 7pjs:I, 7pjt:I, 7pju:I, 7pjv:I, 7pjw:I, 7pjx:I, 7pjy:I, 7pjz:I, 8pkl:k, 6q97:I, 6q98:I, 6q9a:I, 7qg8:V, 7qgh:V, 7qgn:V, 7qgr:V, 8qk7:I, 6s0k:J, 7sa4:I, 7ss9:i, 7ssd:i, 7ssl:i, 7ssn:i, 7sso:i, 7ssw:i, 7st2:i, 7st6:i, 7st7:i, 7tos:L11, 4u1u:BI, 4u1u:DI, 4u1v:BI, 4u1v:DI, 4u20:BI, 4u20:DI, 4u24:BI, 4u24:DI, 4u25:BI, 4u25:DI, 4u26:BI, 4u26:DI, 4u27:BI, 4u27:DI, 5u4i:J, 6u48:CJ, 5u9f:11, 5u9g:11, 7ug7:LK, 8upo:Y, 8upr:Y, 8uql:Y, 8uqm:Y, 8uqp:Y, 8ur0:Y, 8urh:Y, 8uri:Y, 8urx:Y, 8ury:Y, 4uy8:I, 5uyk:11, 5uyl:11, 5uym:11, 5uyn:11, 5uyp:11, 5uyq:11, 4v4h:BI, 4v4h:DI, 4v4q:BI, 4v4q:DI, 4v4v:BG, 4v4w:BG, 4v50:BI, 4v50:DI, 4v52:BI, 4v52:DI, 4v53:BI, 4v53:DI, 4v54:BI, 4v54:DI, 4v55:BI, 4v55:DI, 4v56:BI, 4v56:DI, 4v57:BI, 4v57:DI, 4v5b:AI, 4v5b:CI, 4v5h:BI, 4v5y:BI, 4v5y:DI, 4v64:BI, 4v64:DI, 4v65:B5, 4v66:B5, 4v69:BI, 4v6c:BI, 4v6c:DI, 4v6d:BI, 4v6d:DI, 4v6e:BI, 4v6e:DI, 4v6k:AJ, 4v6l:BJ, 4v6m:BI, 4v6n:AK, 4v6o:BK, 4v6p:BK, 4v6q:BK, 4v6r:BK, 4v6s:AK, 4v6t:BI, 4v6v:BK, 4v6y:BI, 4v6z:BI, 4v70:BI, 4v71:BI, 4v72:BI, 4v73:BI, 4v74:BI, 4v75:BI, 4v76:BI, 4v77:BI, 4v78:BI, 4v79:BI, 4v7a:BI, 4v7b:BI, 4v7c:BK, 4v7d:AK, 4v7i:AI, 4v7s:BI, 4v7s:DI, 4v7t:BI, 4v7t:DI, 4v7u:BI, 4v7u:DI, 4v7v:BI, 4v7v:DI, 4v85:BI, 4v89:BI, 4v9c:BI, 4v9c:DI, 4v9d:CI, 4v9d:DI, 4v9o:AI, 4v9o:CI, 4v9o:EI, 4v9o:GI, 4v9p:AI, 4v9p:CI, 4v9p:EI, 4v9p:GI, 8vs9:L11, 8vsa:L11, 8w51:J, 5wdt:I, 6wd0:i, 6wd1:i, 6wd2:i, 6wd3:i, 6wd4:i, 6wd5:i, 6wd6:i, 6wd7:i, 6wd8:i, 6wd9:i, 6wda:i, 6wdb:i, 6wdc:i, 6wdd:i, 6wde:i, 6wdf:i, 6wdg:i, 6wdh:i, 6wdi:i, 6wdj:i, 6wdk:i, 6wdl:i, 6wdm:i, 5we4:I, 5we6:I, 4wf1:BI, 4wf1:DI, 5wf0:I, 5wfk:I, 5wfs:I, 6wnt:i, 6wnv:i, 6wnw:i, 4woi:BI, 4woi:CI, 4www:RI, 4www:YI, 6xz7:I, 6xza:I2, 6xzb:I2, 4ybb:CJ, 4ybb:DJ, 7yla:Q, 6ysr:I, 6yss:I, 6yst:I, 6ysu:I, 6ztj:BJ
3 6dzi:J 133 133 0.6567 0.6617 0.6617 5.75e-58 6dzp:J, 8fr8:S, 8kab:J, 5o60:J, 5o61:J, 7s0s:K, 8v9j:J, 8v9k:J, 8v9l:J, 7xam:J, 8xz3:J, 7y41:J, 5zeb:J, 5zep:J, 5zet:J
4 3j3v:6 141 131 0.6418 0.6099 0.6565 9.28e-56 7aqc:I, 7aqd:I, 7as8:K, 7as9:K, 7asa:K, 1c04:C, 1hc8:A, 1hc8:B, 3j3w:6, 3j9w:BK, 7o5b:q, 7ope:K, 1qa6:A, 1qa6:B, 7qgu:I, 7qh4:I, 1y39:A, 1y39:B
5 2jq7:A 134 132 0.6194 0.6194 0.6288 4.48e-55 1mms:A, 1mms:B, 1oln:A, 4v4p:AL, 4v4r:BK, 4v4s:BK, 4v4t:BK
6 8a57:E 140 133 0.6119 0.5857 0.6165 1.18e-54 8uu8:H
7 5d8b:G 147 134 0.5896 0.5374 0.5896 4.33e-51 5a9z:AJ, 5aa0:AJ, 6c5l:BK, 6c5l:DK, 3cjt:B, 3cjt:F, 3cjt:J, 3cjt:N, 5d8b:CB, 6gsl:48, 5hau:1K, 5hau:2K, 5imq:3, 5imr:3, 5j8b:K, 4v4x:BL, 4v4y:BL, 4v4z:BL, 4v5e:BK, 4v5e:DK, 4v5f:BK, 4v5f:DK, 4v5j:BK, 4v5j:DK, 4v5m:BK, 4v5n:BK, 4v67:BK, 4v67:DK, 4v68:BL, 4v6f:DL, 4v9h:BK, 4v9j:BK, 4v9j:DK, 4v9k:BK, 4v9k:DK, 4v9l:BK, 4v9l:DK, 4v9m:BK, 4v9m:DK, 4v9n:BK, 4v9n:DK, 4w29:BK, 4w29:DK, 4w2e:K, 4wpo:AL, 4wpo:CL, 4wqf:AL, 4wqf:CL, 4wqu:AL, 4wqu:CL, 4wqy:AL, 4wqy:CL, 4xej:AL11, 4xej:BL11, 5zlu:f
8 3cf5:F 144 134 0.5821 0.5417 0.5821 9.11e-50 3dll:F, 5dm6:F, 5dm7:F, 4io9:F, 4ioa:F, 4ioc:F, 5jvg:F, 3pio:F, 3pip:F, 1sm1:G, 4v49:BG, 4v4a:BG, 4v4g:BJ, 4v4g:DJ, 4v4g:FJ, 4v4g:HJ, 4v4g:JJ, 1xbp:G, 2zjp:F, 2zjq:F, 2zjr:F
9 8fmw:AK 139 133 0.5448 0.5252 0.5489 5.61e-46 8fn2:K
10 4v61:BK 145 133 0.5149 0.4759 0.5188 1.17e-42 5mmi:J, 5mmm:J
11 3cjq:B 121 134 0.5149 0.5702 0.5149 4.54e-39 3cjq:E, 3cjq:H
12 6xyw:Ai 138 134 0.4627 0.4493 0.4627 9.79e-37
13 6ywe:g 147 141 0.4701 0.4286 0.4468 3.54e-33 6yws:g, 6ywv:g, 6ywx:g, 6ywy:g
14 6gaw:BK 176 136 0.4403 0.3352 0.4338 8.67e-31 7a5f:J3, 7a5g:J3, 7a5h:J, 7a5i:J3, 7a5j:J, 7a5k:J3, 5aj4:BK, 8any:J, 6gb2:BK, 6i9r:J, 3j7y:J, 3j9m:J, 8k2a:LK, 8k2b:LK, 7l08:J, 7l20:J, 7nqh:BK, 7nql:BK, 7nsh:BK, 7nsi:BK, 7nsj:BK, 6nu2:J, 6nu3:J, 7o9k:J, 7o9m:J, 7odr:J, 7ods:J, 7odt:J, 7of0:J, 7of2:J, 7of3:J, 7of4:J, 7of5:J, 7of6:J, 7of7:J, 7og4:XJ, 7oi6:J, 7oi7:J, 7oi8:J, 7oi9:J, 7oia:J, 7oib:J, 7oic:J, 7oid:J, 7oie:J, 8oin:BQ, 8oiq:BQ, 8oir:BQ, 8oit:BQ, 5ool:J, 5oom:J, 7pd3:J, 8pk0:J, 7po4:J, 7qi4:J, 7qi5:J, 7qi6:J, 8qsj:J, 8qu1:J, 8qu5:J, 4v19:K, 6vlz:J, 6vmi:J, 8xt0:LK, 8xt1:LK, 8xt2:LK, 8xt3:LK, 6ydp:BK, 6ydw:BK, 6zm5:J, 6zm6:J, 6zs9:XJ, 6zsa:XJ, 6zsb:XJ, 6zsc:XJ, 6zsd:XJ, 6zse:XJ, 6zsg:XJ
15 7ood:h 128 131 0.4104 0.4297 0.4198 8.73e-28 7p6z:h, 7pah:h, 7pai:h, 7paj:h, 7pak:h, 7pal:h, 7pam:h, 7pan:h, 7pao:h, 7paq:h, 7par:h, 7pas:h, 7pat:h, 7pau:h, 7ph9:h, 7pha:h, 7phb:h, 7phc:h, 7pi8:h, 7pi9:h, 7pia:h, 7pib:h, 7pic:h, 7pio:h, 7pip:h, 7piq:h, 7pir:h, 7pis:h, 7pit:h
16 5d8h:C 158 135 0.3731 0.3165 0.3704 1.42e-23 5dar:C, 5dar:F
17 4v4n:AH 134 130 0.3433 0.3433 0.3538 1.94e-19 4v6u:BH
18 4v9f:I 145 134 0.3284 0.3034 0.3284 8.74e-19 3cc2:I, 3cc4:I, 3cc7:I, 3cce:I, 3ccj:I, 3ccl:I, 3ccm:I, 3ccq:I, 3ccr:I, 3ccs:I, 3ccu:I, 3ccv:I, 3cd6:I, 3cma:I, 3cme:I, 3g4s:I, 3g6e:I, 3g71:I, 3i55:I, 3i56:I, 2otj:I, 2otl:I, 2qa4:I, 2qex:I, 1s72:I, 1vq4:I, 1vq5:I, 1vq6:I, 1vq7:I, 1vq8:I, 1vq9:I, 1vqk:I, 1vql:I, 1vqm:I, 1vqn:I, 1vqo:I, 1vqp:I, 1yhq:I, 1yi2:I, 1yij:I, 1yit:I, 1yj9:I, 1yjn:I, 1yjw:I
19 6z1p:An 158 135 0.3209 0.2722 0.3185 5.47e-18
20 7aih:E 326 140 0.3284 0.1350 0.3143 3.32e-14 7am2:E, 7ane:E
21 6hiv:AK 323 140 0.3060 0.1269 0.2929 5.37e-10 6hix:AK
22 8idt:y 165 135 0.2313 0.1879 0.2296 0.015 7a01:M2, 5a8l:G, 5aj0:Aq, 9bdn:AL12, 9bdp:AL12, 8bhf:f1, 8bpo:r2, 8btk:Bt, 6d90:t, 6d9j:t, 9f1b:Bt, 9f1c:Bt, 9f1d:Bt, 8fkr:BA, 8fks:BA, 8fkt:BA, 8fku:BA, 8fkv:BA, 8fkw:BA, 8fkx:BA, 8fky:BA, 8fkz:BA, 8fl0:BA, 8fl2:BA, 8fl3:BA, 8fl4:BA, 8fl6:BA, 8fl7:BA, 8fl9:BA, 8fla:BA, 8flb:BA, 8flc:BA, 6frk:4, 6ftg:t, 6fti:t, 6ftj:t, 8g5z:LK, 8g60:LK, 8g6j:LK, 6gz3:Aq, 6gz4:Aq, 6gz5:Aq, 6hcf:t3, 6hcj:u3, 6hcm:t3, 6hcq:u3, 8idy:y, 8ine:y, 8inf:y, 8ink:y, 8ipd:y, 8ipx:y, 8ipy:y, 8ir1:y, 8ir3:y, 3j7p:K, 3j92:t, 3jag:t, 3jah:t, 3jai:t, 3jaj:K, 3jan:K, 8k2c:Lt, 7ls1:k, 7ls2:k, 5lzs:t, 5lzt:t, 5lzu:t, 5lzv:t, 5lzw:t, 5lzx:t, 5lzy:t, 5lzz:t, 6mtd:t, 6mte:t, 7nwg:u3, 7nwh:t, 7nwi:t, 7o7y:Bt, 7o7z:Bt, 7o80:Bt, 7o81:Bt, 6olg:Aq, 8p2k:Bt, 8q87:Bt, 6r5q:t, 6r6g:t, 6r6p:t, 6r7q:t, 8scb:t, 6sgc:t2, 6t59:t3, 4v5z:Bi, 4v6x:CK, 8xsx:LK, 8xsy:Lt, 8xsz:Lt, 8yoo:Lt, 8yop:Lt, 6zm7:Lt, 6zme:Lt, 6zmi:Lt, 6zmo:Lt, 6zvk:M2
23 4kbf:A 365 64 0.1642 0.0603 0.3438 0.25 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
24 7f09:C 67 53 0.0970 0.1940 0.2453 0.48
25 5an9:D 166 133 0.2537 0.2048 0.2556 0.54 5anb:D, 5anc:D, 6qkl:D
26 8pv1:LK 158 135 0.2388 0.2025 0.2370 0.73 8i9t:LK, 8i9v:LK, 8i9w:LK, 8i9x:LK, 8i9y:LK, 8i9z:LK, 8ia0:LK, 7olc:LK, 7old:LK, 8oo0:LK, 8pv2:LK, 8pv3:LK, 8pv4:LK, 8pv5:LK, 8pv6:LK, 8pv7:LK, 8pv8:LK, 8pvk:LK, 8pvl:LK, 7z3n:LK, 7z3o:LK
27 6v6s:k 370 60 0.1567 0.0568 0.3500 1.1 6v5v:g, 6v6s:a, 6v6s:b, 6v6s:c, 6v6s:d, 6v6s:e, 6v6s:f, 6v6s:g, 6v6s:h, 6v6s:i, 6v6s:j, 6v6s:l, 6v6s:m, 6v6s:t
28 6izr:1 349 43 0.1269 0.0487 0.3953 1.5 6ixw:C, 6ixw:B, 6ixw:A, 6izr:2, 6izr:A, 6izr:B, 6izr:D, 6izr:E, 6izr:G, 6izr:H, 6izr:J, 6izr:K, 6izr:M, 6izr:N, 6izr:P, 6izr:Q, 6izr:b, 6izr:c, 6izr:e, 6izr:f, 6izr:h, 6izr:i, 6izr:k, 6izr:l, 6izr:n, 6izr:o, 6izr:q, 6izr:r, 6izr:t, 6izr:u, 6izr:w, 6izr:x, 6izv:0, 6izv:1
29 5myj:BW 88 47 0.1045 0.1591 0.2979 3.0
30 7c79:B 793 38 0.0746 0.0126 0.2632 4.5 6agb:B, 6ah3:B, 7c7a:B, 6w6v:B
31 6zhh:A 883 48 0.0970 0.0147 0.2708 7.5 6zhf:A, 6zhg:A, 6zhh:B, 6zhh:C, 6zhh:D, 6zhh:E, 6zhh:F, 6zhh:G, 6zhh:H
32 6x0l:P 474 38 0.1045 0.0295 0.3684 8.6 7aeo:A, 5dsy:A, 5dsy:B, 5dsy:C, 5dsy:D, 6f1k:A, 6f5b:A, 6f5b:B, 6f5f:A, 6f5f:D, 6f5f:B, 8he8:A, 8he8:B, 8he8:C, 8hkn:B, 8hkn:A, 8hko:A, 8hko:B, 8hks:A, 8hks:B, 8hks:C, 8hks:D, 8hlj:A, 8hlj:B, 8hlq:A, 8hlq:B, 8jny:A, 8jny:B, 3kcz:A, 3kcz:B, 3kjd:A, 3kjd:B, 4pjv:A, 4pjv:B, 7r59:A, 4tvj:A, 4tvj:B, 6tx3:B, 6usj:U, 6x0l:R, 6x0m:p, 6x0m:P, 6x0n:P, 6x0n:R, 4zzx:A, 4zzx:B, 4zzy:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218