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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IIFPEDFIWGAATSSYQIEGAFNEDGKGESIWDRFSHTPGKIENGDTGDIACDHYHLYREDIELMKEIGIRSYRFSTSWP
RILPEGKGRVNQKGLDFYKRLVDNLLKANIRPMITLYHWDLPQALQDKGGWTNRDTAKYFAEYARLMFEEFNGLVDLWVT
HNEPWVVAFEGHAFGNHAPGTKDFKTALQVAHHLLLSHGMAVDIFREEDLPGEIGITLNLTPAYPAGDSEKDVKAASLLD
DYINAWFLSPVFKGSYPEELHHIYEQNLGAFTTQPGDMDIISRDIDFLGINYYSRMVVRHKPGDNLFNAEVVKMEDRPST
EMGWEIYPQGLYDILVRVNKEYTDKPLYITENGAAFDDKLTEEGKIHDEKRINYLGDHFKQAYKALKDGVPLRGYYVWSL
MDNFEWAYGYSKRFGLIYVDYENGNRRFLKDSALWYREVIEKGQV

The query sequence (length=445) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ptv:A 445 445 1.0000 1.0000 1.0000 0.0 4ptv:B, 4ptw:A, 4ptw:B, 4ptx:A, 4ptx:B
2 8ivy:A 451 442 0.5461 0.5388 0.5498 0.0 8ivy:B
3 6z1m:A 423 442 0.5663 0.5957 0.5701 0.0 6z1m:B, 6z1m:C
4 2jal:B 444 441 0.5258 0.5270 0.5306 1.69e-169 2cbu:A, 2cbu:B, 2cbv:A, 2cbv:B, 2ces:A, 2ces:B, 2cet:A, 2cet:B, 2j75:A, 2j75:B, 2j77:A, 2j77:B, 2j78:A, 2j78:B, 2j79:A, 2j79:B, 2j7b:A, 2j7b:B, 2j7c:A, 2j7c:B, 2j7d:A, 2j7d:B, 2j7e:A, 2j7e:B, 2j7f:A, 2j7f:B, 2j7g:A, 2j7g:B, 2j7h:A, 2j7h:B, 2jal:A, 5n6s:A, 5n6s:B, 5n6s:C, 5n6s:D, 5n6t:A, 5n6t:B, 1oif:A, 1oif:B, 1oim:A, 1oim:B, 1oin:A, 1oin:B, 5oss:B, 1uz1:A, 1uz1:B, 2vrj:A, 2vrj:B, 1w3j:A, 1w3j:B, 2wbg:A, 2wbg:B, 2wbg:C, 2wbg:D, 2wc3:A, 2wc3:B, 2wc3:C, 2wc3:D, 2wc4:A, 2wc4:B, 2wc4:C, 2wc4:D
5 4hz7:A 441 439 0.5303 0.5351 0.5376 5.83e-168 4hz8:A
6 6z1h:A 382 439 0.5281 0.6152 0.5353 1.42e-163
7 6qwi:A 448 438 0.4989 0.4955 0.5068 5.37e-162 1bgg:B, 1bgg:C, 1bgg:D, 1e4i:A, 6qwi:B, 6r4k:A, 6r4k:B, 1uyq:A
8 3wh6:A 443 439 0.4989 0.5011 0.5057 5.91e-159 5ayi:A, 3wh7:A, 3wh8:A
9 5ns8:A 440 436 0.4854 0.4909 0.4954 4.13e-157 5ns8:B, 5ns8:C
10 7wdo:A 445 438 0.4787 0.4787 0.4863 3.02e-155 7wdn:A, 7wdp:A, 7wdr:A, 7wds:A, 7wdv:A
11 2jie:A 445 443 0.4584 0.4584 0.4605 3.54e-151 2o9r:A, 2o9t:A, 2z1s:A
12 5gnx:A 451 441 0.4787 0.4723 0.4830 7.16e-149 5gnx:B, 5gny:A, 5gny:B, 5gny:C, 5gny:D, 5gnz:A, 5gnz:B, 5gnz:C, 5gnz:D, 5gnz:H, 5gnz:I, 5gnz:J, 5gnz:K
13 1gnx:A 447 448 0.4899 0.4877 0.4866 2.34e-146 1gnx:B, 1gon:A
14 6jfp:A 444 441 0.4652 0.4662 0.4694 3.87e-145
15 6m6l:B 445 437 0.4472 0.4472 0.4554 2.07e-142
16 5yj7:C 490 455 0.4427 0.4020 0.4330 9.83e-126
17 6rjm:B 456 442 0.4135 0.4035 0.4163 6.44e-123 6rjm:A, 6rjo:A, 6rjo:B, 6rk2:A, 6rk2:B
18 5yif:A 459 452 0.4157 0.4031 0.4093 5.15e-122 5yif:B
19 3wq5:A 475 471 0.4112 0.3853 0.3885 4.59e-114 3wq5:B, 3wq6:A, 3wq6:B
20 3ahy:B 466 457 0.4270 0.4077 0.4158 1.73e-109 3ahy:A, 3ahy:C, 3ahy:D
21 3gnr:A 478 475 0.4045 0.3766 0.3789 4.47e-109 3wba:A, 3wbe:A
22 3aiq:A 491 469 0.3955 0.3585 0.3753 7.20e-106 3air:A, 3ais:A, 3aiv:A, 3aiw:A
23 2e40:A 459 463 0.4157 0.4031 0.3996 9.97e-105 2e40:B
24 8b80:A 474 465 0.3978 0.3734 0.3806 1.53e-104 8b81:A, 8b81:B, 5okb:B, 5okb:C, 5okb:D, 5oke:C, 5oke:D, 5oke:A, 5oke:B, 5okg:C, 5okg:D, 5okg:A, 5okg:B, 5okk:A, 5okk:B, 5okq:A, 5okq:B, 5okr:A, 5okr:B, 5oks:A, 5oks:B, 4zen:A, 4zen:B, 4zep:A, 4zep:B, 4zfm:D, 4zfm:A, 4zfm:B, 4zfm:C
25 1v03:A 487 471 0.4045 0.3696 0.3822 2.39e-103
26 2jf6:B 472 468 0.4067 0.3835 0.3868 5.02e-103 2jf6:A, 3zj7:A, 3zj7:B, 3zj8:A, 3zj8:B
27 7d6a:B 477 475 0.3978 0.3711 0.3726 1.53e-100 7d6a:A, 7d6b:A, 7d6b:B
28 3ahv:A 472 464 0.3708 0.3496 0.3556 1.54e-99 3aht:A, 3aht:B, 3ahv:B, 7bzm:A, 7bzm:B, 3f4v:A, 3f4v:B, 3f5j:A, 3f5j:B, 3f5k:A, 3f5k:B, 3f5l:A, 3f5l:B, 4qlj:A, 4qlj:B, 4qlk:A, 4qlk:B, 4qll:A, 4qll:B, 2rgl:A, 2rgl:B, 2rgm:A, 2rgm:B, 3scn:A, 3scn:B, 3sco:A, 3sco:B, 3scp:A, 3scp:B, 3scq:A, 3scq:B, 3scr:A, 3scr:B, 3scs:A, 3scs:B, 3sct:A, 3sct:B, 3scu:A, 3scu:B, 3scv:A, 3scv:B, 3scw:A, 3scw:B
29 3ptk:A 478 474 0.4000 0.3724 0.3755 2.31e-99 3ptk:B, 3ptm:A, 3ptm:B, 3ptq:A, 3ptq:B
30 3u57:A 471 464 0.4090 0.3864 0.3922 4.28e-98 4atl:A, 4atl:B, 4ek7:A, 4ek7:B, 3u57:B, 3u5y:A, 3u5y:B, 3zj6:A, 3zj6:B
31 4jie:A 484 464 0.3888 0.3574 0.3728 5.25e-97 4re2:A, 4re3:A, 4re4:A
32 3vif:A 473 471 0.4112 0.3869 0.3885 9.75e-97 3ahz:A, 3ai0:A, 3vig:A, 3vij:A, 3vik:A, 3vil:A, 3vim:A, 3vin:A, 3vio:A, 3vip:A
33 1e55:A 492 478 0.3798 0.3435 0.3536 1.51e-92 1e1f:A, 1e1f:B, 1e4n:A, 1e4n:B, 1e55:B, 1e56:A, 1e56:B, 1h49:B, 1h49:A, 1v08:A, 1v08:B
34 4pbg:A 468 468 0.3775 0.3590 0.3590 8.79e-90 4pbg:B
35 2e9l:A 466 471 0.3640 0.3476 0.3439 2.80e-84 2e9m:A, 3vkk:A, 2zox:A
36 7z1i:A 493 474 0.3528 0.3185 0.3312 1.87e-78 7z1i:B, 7z1i:D
37 5foo:A 463 458 0.3348 0.3218 0.3253 4.79e-78 5foo:B, 5foo:C, 5foo:D, 5foo:E, 5foo:F
38 5naq:A 461 458 0.3551 0.3427 0.3450 1.76e-76 5naq:B, 5naq:C, 5naq:D, 5naq:E, 5naq:F
39 1dwa:M 499 474 0.3393 0.3026 0.3186 6.50e-74 1dwf:M, 1dwg:M, 1dwh:M, 1dwi:M, 1dwj:M, 1e4m:M, 1e6q:M, 1e6s:M, 1e6x:M, 1e70:M, 1e71:M, 1e72:M, 1e73:M, 1myr:A, 1w9b:M, 1w9d:M, 2wxd:M
40 5w21:A 922 450 0.3708 0.1790 0.3667 4.46e-73 7ysh:A, 7ysu:A, 7ysw:A
41 5w21:A 922 472 0.2966 0.1432 0.2797 3.09e-38 7ysh:A, 7ysu:A, 7ysw:A
42 4ipn:E 463 460 0.3506 0.3369 0.3391 7.01e-68 4ipn:B
43 4f66:A 478 474 0.3461 0.3222 0.3249 5.58e-64 4f66:B, 4f79:A, 4gpn:A, 4gpn:B
44 3qom:A 479 467 0.3506 0.3257 0.3340 3.18e-61
45 5van:A 861 452 0.3258 0.1684 0.3208 3.43e-58 6nfj:A, 6nfj:D, 5vaq:A
46 5van:A 861 416 0.2652 0.1370 0.2837 4.94e-37 6nfj:A, 6nfj:D, 5vaq:A
47 7f1n:A 502 498 0.3079 0.2729 0.2751 6.25e-48 7f1n:B
48 4ha3:A 489 502 0.3213 0.2924 0.2849 1.39e-45 4ha4:A
49 6m4f:C 543 484 0.3146 0.2578 0.2893 3.33e-45 6m4e:A, 6m4f:E, 6m55:A, 6m55:D
50 2ceq:A 489 495 0.2876 0.2618 0.2586 1.26e-42 2ceq:B, 2cer:A, 2cer:B, 4ean:A, 4ean:B, 5ixe:A, 5ixe:B, 1uwr:A, 1uwr:B, 1uws:B, 1uws:A, 1uwt:A, 1uwt:B, 1uwu:A, 1uwu:B, 7uz1:A, 7uz1:B, 7uz2:A, 7uz2:B
51 8kaq:D 364 168 0.1348 0.1648 0.3571 2.99e-26
52 8kaq:D 364 133 0.1011 0.1236 0.3383 6.93e-15
53 8kaq:A 401 169 0.1348 0.1496 0.3550 3.92e-26 8kaq:B, 8kaq:C
54 8kaq:A 401 154 0.1124 0.1247 0.3247 1.63e-15 8kaq:B, 8kaq:C
55 8j9f:D 749 53 0.0449 0.0267 0.3774 0.91 8j9f:A, 8j9f:B
56 8wil:A 574 73 0.0427 0.0331 0.2603 1.3 8wim:A
57 3nco:A 313 106 0.0697 0.0990 0.2925 1.5 3nco:B, 3rjy:A
58 6agi:B 322 136 0.0742 0.1025 0.2426 1.6 6agi:A
59 5h4r:A 375 125 0.0674 0.0800 0.2400 1.6
60 6wev:AbA 817 104 0.0607 0.0330 0.2596 5.3 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
61 6riw:A 923 61 0.0404 0.0195 0.2951 5.5
62 5j14:A 450 49 0.0315 0.0311 0.2857 6.1 5j14:B, 5j7z:A
63 6xyw:Bh 123 51 0.0449 0.1626 0.3922 7.0
64 2aqx:A 289 34 0.0247 0.0381 0.3235 7.7 2aqx:B
65 4fr8:C 496 98 0.0472 0.0423 0.2143 8.6 1a4z:A, 1a4z:B, 1a4z:C, 1a4z:D, 1cw3:A, 1cw3:B, 1cw3:C, 1cw3:D, 1cw3:E, 1cw3:F, 1cw3:G, 1cw3:H, 8dr9:A, 8dr9:B, 4fqf:A, 4fqf:B, 4fqf:C, 4fqf:D, 4fr8:A, 4fr8:B, 4fr8:D, 4fr8:E, 4fr8:F, 4fr8:G, 4fr8:H, 3inj:A, 3inj:B, 3inj:C, 3inj:D, 3inj:E, 3inj:F, 3inj:G, 3inj:H, 3inl:A, 3inl:B, 3inl:C, 3inl:D, 3inl:E, 3inl:F, 3inl:G, 3inl:H, 4kwf:A, 4kwf:B, 4kwf:E, 4kwf:H, 4kwg:A, 4kwg:H, 5l13:A, 5l13:B, 5l13:C, 5l13:D, 5l13:E, 5l13:F, 5l13:G, 5l13:H, 3n82:A, 3n82:B, 3n82:C, 3n82:D, 3n82:E, 3n82:F, 3n82:G, 3n82:H, 3n83:A, 3n83:B, 3n83:C, 3n83:D, 3n83:E, 3n83:F, 3n83:G, 3n83:H, 1nzw:A, 1nzw:B, 1nzw:C, 1nzw:D, 1nzw:E, 1nzw:F, 1nzw:G, 1nzw:H, 1nzx:A, 1nzx:B, 1nzx:C, 1nzx:D, 1nzx:E, 1nzx:F, 1nzx:G, 1nzx:H, 1nzz:A, 1nzz:B, 1nzz:C, 1nzz:D, 1nzz:E, 1nzz:F, 1nzz:G, 1nzz:H, 1o00:A, 1o00:B, 1o00:C, 1o00:D, 1o00:E, 1o00:F, 1o00:G, 1o00:H, 1o01:A, 1o01:B, 1o01:C, 1o01:D, 1o01:E, 1o01:F, 1o01:G, 1o01:H, 1o02:A, 1o02:B, 1o02:C, 1o02:D, 1o02:E, 1o02:F, 1o02:G, 1o02:H, 1o04:A, 1o04:B, 1o04:C, 1o04:D, 1o04:E, 1o04:F, 1o04:G, 1o04:H, 2onm:A, 2onm:B, 2onm:C, 2onm:D, 2onm:E, 2onm:F, 2onm:G, 2onm:H, 2onm:I, 2onm:J, 2onm:K, 2onm:L, 2onp:A, 2onp:B, 2onp:C, 2onp:D, 2onp:E, 2onp:F, 2onp:G, 2onp:H, 3sz9:A, 3sz9:B, 3sz9:C, 3sz9:D, 3sz9:E, 3sz9:F, 3sz9:G, 3sz9:H, 2vle:A, 2vle:B, 2vle:C, 2vle:D, 2vle:E, 2vle:F, 2vle:G, 2vle:H
66 1v9p:A 584 61 0.0427 0.0325 0.3115 9.1 1dgs:A, 1dgs:B, 1v9p:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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