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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IHNFGAGPAAMAKEVIEATAKAVNNFWEGLSILEISHRSKEWINVMNETKALMKEVMDIPEGYEILFFGGGASLQFLMVA
MNLLNKKACYLDTGVWASKAIKEAENIGEVKIIGTSKDKNYTYIPEYQIPSDYDYFHITTNNTIYGTEIRKDIESPIPLV
ADMSSDILSKPIDISKYSLIYAGAQKNCGAAGVTIVIIKKEILGKVQRKIPIILDYQVHILNNSMYNTPPVISIFTVNQT
LKYIKKIGGLKKIQELNEEKARLLYAEIDRNKIFRGTVRKKDRSIMNVCFVYKQLENEFSEYALQKGIIGIKGHRSVGGF
RASIYNAVTIESVQALIKCMHDFEQ

The query sequence (length=345) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5yb0:B 349 349 1.0000 0.9885 0.9885 0.0 5yb0:A, 5yb0:C, 5yb0:D, 5yb0:E, 5yb0:F, 5yb0:G, 5yb0:H, 5yb0:I, 5yb0:J, 5yb0:K, 5yd2:A, 5yd2:B
2 1bt4:A 361 354 0.4580 0.4377 0.4463 4.79e-105 2c0r:A, 2c0r:B, 1w3u:A
3 4azj:A 360 355 0.4609 0.4417 0.4479 1.11e-104 4azj:B, 4azk:A, 4azk:B, 2bhx:A, 2bhx:B, 2bi1:A, 2bi1:B, 2bi2:A, 2bi2:B, 2bi3:A, 2bi3:B, 2bi5:A, 2bi5:B, 2bi9:A, 2bi9:B, 2bia:A, 2bia:B, 2bie:A, 2bie:B, 2big:A, 2big:B, 1w23:A, 1w23:B
4 6czy:A 362 358 0.4261 0.4061 0.4106 2.45e-94 6czy:B, 6czy:C, 6czy:D, 6czz:A, 6czz:B, 6czz:C, 6czz:D
5 3qbo:B 359 357 0.4290 0.4123 0.4146 2.49e-89 3qbo:A
6 1bjo:A 360 358 0.4174 0.4000 0.4022 2.01e-86 1bjo:B
7 8a5v:E 366 358 0.4145 0.3907 0.3994 5.95e-84 8a5v:C, 8a5v:F, 8a5v:B, 8a5v:A, 8a5v:G, 8a5v:H, 8a5w:D, 8a5w:C, 8a5w:E, 8a5w:F, 8a5w:B, 8a5w:A, 8a5w:H, 3e77:A, 3e77:B
8 7t7j:B 360 358 0.4029 0.3861 0.3883 4.82e-82 7t7j:A
9 6xdk:D 359 353 0.3739 0.3593 0.3654 3.85e-80 6xdk:B, 6xdk:A, 6xdk:C
10 3qm2:B 331 355 0.3826 0.3988 0.3718 1.53e-68 3qm2:A
11 2fyf:A 368 357 0.2290 0.2147 0.2213 4.97e-20 2fyf:B, 3vom:A, 3vom:B
12 3ffr:A 361 362 0.2203 0.2105 0.2099 2.10e-08
13 2dr1:A 381 290 0.2000 0.1811 0.2379 2.36e-06 2dr1:B
14 3kgw:B 388 251 0.1652 0.1469 0.2271 0.17 3kgw:A, 3kgx:A
15 7kgm:A 512 77 0.0609 0.0410 0.2727 0.24
16 7kgn:A 462 77 0.0609 0.0455 0.2727 0.66
17 5dzt:A 886 108 0.1014 0.0395 0.3241 1.5
18 1ze1:D 284 47 0.0522 0.0634 0.3830 3.0
19 3cg3:A 315 156 0.1072 0.1175 0.2372 3.1
20 3e70:C 307 69 0.0551 0.0619 0.2754 3.3
21 8yl9:A 346 99 0.0609 0.0607 0.2121 3.5 8yl9:B, 8yl9:I
22 6ntw:A 505 77 0.0580 0.0396 0.2597 3.6
23 1ze1:A 308 47 0.0522 0.0584 0.3830 4.1 2ab4:A, 1r3e:A, 1ze1:B, 1ze1:C, 1ze2:A
24 3cg1:A 293 88 0.0667 0.0785 0.2614 4.6 3cg1:B
25 6v11:C 503 61 0.0493 0.0338 0.2787 5.7 6v11:A, 6v11:B, 6v11:F
26 6on2:B 524 62 0.0522 0.0344 0.2903 6.4 6on2:C, 6on2:A, 6on2:D, 6on2:E, 6on2:F
27 6v11:E 464 62 0.0522 0.0388 0.2903 6.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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