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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IEYRSLHTSQLTLSEKEALYDLLIEGFEGDFSHDDFAHTLGGMHVMAFDQQKLVGHVAIIQRHMALDNTPISVGYVEAMV
VEQSYRRQGIGRQLMLQTNKIIASCYQLGLLSASDDGQKLYHSVGWQIWKGKLFELKQGSYIRSIEEEGGVMGWKADGEV
DFTASLYCDFRGGDQW

The query sequence (length=176) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5us1:A 189 176 1.0000 0.9312 1.0000 5.56e-130 7jzs:A, 5us1:B, 5us1:C, 5us1:D, 5us1:E, 5us1:F, 5us1:G, 5us1:H, 5us1:I, 5us1:K, 5us1:L, 6vou:A, 6vou:B, 6vr2:A, 6vr2:B, 6vr3:A, 6vr3:B, 6vta:A, 6vta:B
2 1m4d:A 181 173 0.3239 0.3149 0.3295 8.25e-34 1m4d:B, 1m4g:A, 1m4g:B, 1m4i:A, 1m4i:B
3 7cs1:A 191 187 0.3239 0.2984 0.3048 4.50e-21 7cs0:A, 7cs0:B, 7cs1:B, 7csi:A, 7csi:B, 7csj:A, 7csj:B
4 2q0y:A 153 54 0.1080 0.1242 0.3519 0.006
5 5nnp:B 179 66 0.1023 0.1006 0.2727 0.16 5nnp:F
6 5kf2:A 317 80 0.1193 0.0662 0.2625 0.30 5kf1:A, 5kf1:B, 5kf8:A, 5kf9:A, 5kga:A, 5kga:B, 5kgh:A, 5kgh:B, 5kgj:A, 5kgp:A, 5kgp:B
7 1b87:A 181 106 0.1705 0.1657 0.2830 0.49 2a4n:A, 2a4n:B, 1n71:A, 1n71:B, 1n71:C, 1n71:D
8 6yug:A 143 55 0.0852 0.1049 0.2727 0.69 6yug:B
9 6c95:B 160 61 0.0909 0.1000 0.2623 0.79 6ppl:C, 6pw9:C
10 4kvm:E 153 55 0.0852 0.0980 0.2727 0.82 4kvm:F, 4kvm:G, 4kvm:H, 4kvo:E, 4kvo:F, 4kvo:G, 4kvo:H, 4kvx:A, 4kvx:B
11 8wea:A 1206 44 0.0909 0.0133 0.3636 1.1
12 8fhs:A 1282 44 0.0909 0.0125 0.3636 1.1 8eog:K, 8fd7:K, 8hlp:A, 8hma:E, 8hmb:D, 8we6:A, 8we7:A, 8we8:A, 8we9:A
13 5f47:B 152 30 0.0568 0.0658 0.3333 1.2 5f47:A, 5f48:A, 5f48:B, 5f49:A, 5f49:B, 5f49:C, 5f49:D, 5u08:A, 5u08:B, 5u08:C, 5u08:D
14 4hnx:B 213 48 0.0966 0.0798 0.3542 1.2 4hnw:B, 6o07:B, 4xnh:B, 4xpd:B, 4y49:B, 4y49:H, 4y49:N
15 7mx2:A 152 65 0.0852 0.0987 0.2308 1.6 7rb3:A
16 1yvk:A 152 70 0.1080 0.1250 0.2714 1.8 1yvk:B, 1yvk:C, 1yvk:D
17 7wx5:A 288 27 0.0682 0.0417 0.4444 2.1 7wx6:A, 7wx7:A
18 2bei:A 156 57 0.0909 0.1026 0.2807 3.2 2q4v:A
19 1s5k:A 153 79 0.1023 0.1176 0.2278 3.5 1s3z:A, 1s3z:B, 1s5k:B, 1s60:A, 2vbq:A, 2vbq:B
20 7ovv:B 196 26 0.0568 0.0510 0.3846 4.5 7ovv:A
21 1i1d:D 161 56 0.0909 0.0994 0.2857 4.8 1i12:A, 1i12:B, 1i12:C, 1i12:D, 1i1d:A, 1i1d:B, 1i1d:C
22 3pp9:A 176 59 0.0795 0.0795 0.2373 5.0 3pp9:B, 3pp9:C
23 5jph:B 144 99 0.1250 0.1528 0.2222 6.0 5jph:A, 5jph:C
24 6bvc:A 154 55 0.0966 0.1104 0.3091 7.3 1bo4:A, 1bo4:B
25 4hss:A 411 74 0.1080 0.0462 0.2568 7.5 4hsq:A, 4hss:B
26 4evy:A 147 91 0.1136 0.1361 0.2198 8.6 4evy:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218