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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPARFTRVLP
RDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQWLEVFC
EQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMD
REKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARV
VRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNL
PNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLL
IRERLKRRYGPGTSSQAEAARILAASWPQNREDEEKQKLKAAASHLFPFEKL

The query sequence (length=532) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ebw:H 532 532 1.0000 1.0000 1.0000 0.0 8ebs:H, 8ebt:H, 8ebv:H, 8ebx:H
2 7k04:A 524 527 0.2331 0.2366 0.2353 5.73e-25 6cfi:A, 7m2u:A, 2qsg:A, 2qsh:A, 6ubf:A, 6ug1:A, 6uin:A, 4yir:A
3 3esw:A 333 82 0.0508 0.0811 0.3293 0.001 1x3w:A, 1x3z:A
4 2f4m:A 295 108 0.0602 0.1085 0.2963 0.017 2f4o:A
5 5qcd:A 223 114 0.0545 0.1300 0.2544 2.6 2f1g:A, 2f1g:B, 2fq9:A, 2fq9:B, 2fra:A, 2fra:B, 2frq:A, 2frq:B, 2ft2:A, 2ft2:B, 2fud:A, 2fud:B, 2fye:A, 2g6d:A, 2g7y:A, 2g7y:B, 9gj2:A, 9gj2:B, 2h7j:A, 2h7j:B, 2hh5:B, 2hh5:A, 2hhn:B, 2hxz:A, 2hxz:B, 2hxz:C, 3iej:A, 3iej:B, 1ms6:A, 3n3g:A, 3n3g:B, 3n4c:A, 3n4c:B, 1npz:A, 1npz:B, 1nqc:A, 2op3:A, 2op3:B, 3ovx:A, 3ovx:B, 4p6e:A, 4p6e:B, 4p6g:A, 4p6g:B, 4p6g:C, 4p6g:D, 8pi3:A, 5qbu:A, 5qbu:B, 5qbv:A, 5qbv:B, 5qbw:A, 5qbx:A, 5qbx:B, 5qby:A, 5qby:B, 5qbz:A, 5qc0:A, 5qc0:B, 5qc1:A, 5qc1:B, 5qc2:A, 5qc2:B, 5qc3:A, 5qc3:B, 5qc4:A, 5qc4:B, 5qc5:A, 5qc5:B, 5qc6:A, 5qc6:B, 5qc7:A, 5qc7:B, 5qc8:A, 5qc8:B, 5qc9:A, 5qc9:B, 5qca:A, 5qca:B, 5qcb:A, 5qcb:B, 5qcc:A, 5qcc:B, 5qce:A, 5qce:B, 5qcf:A, 5qcg:A, 5qcg:B, 5qch:A, 5qch:B, 5qch:D, 5qch:C, 5qci:A, 5qcj:A, 5qcj:B, 5qcj:C, 2r9m:A, 2r9m:B, 2r9n:A, 2r9n:B, 2r9o:A, 2r9o:B, 8rnd:A, 6yyn:AAA, 6yyn:BBB, 6yyo:AAA, 6yyo:BBB, 6yyp:AAA, 6yyq:AAA, 6yyq:BBB, 6yyq:CCC, 6yyr:AAA, 6yyr:BBB
6 4iub:L 602 162 0.0771 0.0681 0.2531 3.6 5d51:L, 4iuc:L, 4iud:L, 5mdj:L, 5mdk:L, 5mdl:L, 7odg:L, 7odh:L, 8pou:L, 8pov:L, 8pow:L, 8pox:L, 8poz:L, 3rgw:L, 4ttt:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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