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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
IAKNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARFRKMFPLITTLLPKMIARINDWFEEVKAKRGKRPT
AFQFLQEIKPEAVAYITIKTTLACLTSADNTTVQAVASAIGRAIEDEARFGRIRDLEAKHFKKNVEEQLNKRVGHVYKKA
FMQVVEADMLSKGLLGGEAWSSWHKEDSIHVGVRCIEMLIESTGMVSLHRQNAGVVGQDSETIELAPEYAEAIATRAGAL
AGISPMFQPCVVPPKPWTGITGGGYWANGRRPLALVRTHSKKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVI
TKWKHCPVEDIPAIEREELPMKPEDIDMNPEALTAWKRAAAAVYRKDKARKSRRISLEFMLEQANKFANHKAIWFPYNMD
WRGRVYAVSMFNPQGNDMTKGLLTLAKGKPIGKEGYYWLKIHGANCAGVDKVPFPERIKFIEENHENIMACAKSPLENTW
WAEQDSPFCFLAFCFEYAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDEVGGRAVNLLPSETVQDIYGIVAKKVNEI
LQADAINGTDNEVVTVTDENTGEISEKVKLGTKALAGQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQVLEDTIQPAIDS
GKGLMFTQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKTGEILRKRCAVHWVTPDGFPVWQEYKK
PIQTRLNLMFLGQFRLQPTINTNKDSEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSFGTIPADA
ANLFKAVRETMVDTYESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLRDILESDFAFA

The query sequence (length=862) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1msw:D 863 878 0.9780 0.9768 0.9601 0.0 1cez:A, 8dh1:B, 8dh2:B, 8dh3:B, 8dh4:B, 8dh5:B, 3e2e:A, 3e3j:C, 3e3j:B, 1h38:A, 1h38:B, 1h38:C, 1h38:D, 2pi4:A, 2pi5:A, 1qln:A, 1s0v:A, 1s0v:B, 1s0v:C, 1s0v:D
2 8dh2:E 841 878 0.9548 0.9786 0.9374 0.0 8dh0:B, 8dh1:E, 8dh1:I, 8dh2:I, 8dh3:I, 8dh4:E, 8dh5:I, 1s76:D, 1s77:D
3 8dh3:E 825 878 0.9362 0.9782 0.9191 0.0 8dh4:M, 8dh5:E
4 8dh4:I 821 878 0.9304 0.9769 0.9134 0.0 8dh0:J
5 8dh0:F 796 878 0.8991 0.9736 0.8827 0.0
6 8dh3:M 775 877 0.8759 0.9742 0.8609 0.0 8dh0:N
7 8dh2:L 741 878 0.8364 0.9730 0.8212 0.0
8 8dh5:M 740 877 0.8341 0.9716 0.8198 0.0
9 8dh1:L 702 877 0.7877 0.9672 0.7742 0.0
10 8c5s:A 924 788 0.2691 0.2511 0.2944 3.94e-75 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
11 6ymv:A 887 786 0.2610 0.2537 0.2863 2.25e-71
12 6erp:A 1011 779 0.2436 0.2077 0.2696 1.26e-64 6erp:B, 6erq:A, 6erq:B
13 9bdc:E 990 782 0.2425 0.2111 0.2673 1.97e-64 9bdd:E, 4boc:A, 5ola:E, 5ola:F, 8u8u:E, 8u8v:E
14 3spa:A 941 771 0.2367 0.2168 0.2646 8.52e-64 7a8p:A
15 6dt7:B 404 417 0.1056 0.2252 0.2182 3.14e-04 6dt8:B, 6dta:B
16 2ntz:A 183 95 0.0255 0.1202 0.2316 5.3 2ntz:B, 1zx4:A
17 4z3u:B 252 36 0.0151 0.0516 0.3611 6.0 5e8c:A, 5fki:1A, 5fki:1C, 5fki:1E, 5fki:1G, 5fki:1I, 5fki:1K, 5fki:1M, 5fki:1O, 5fki:1Q, 5fki:1S, 5fki:1U, 5fki:1W, 5fki:1Y, 5fki:10, 5fki:12, 5fki:14, 5fki:16, 5fki:18, 5fki:2A, 5fki:2C, 5fki:2E, 5fki:2G, 5fki:2I, 5fki:2K, 5fki:2M, 5fki:2O, 5fki:2Q, 5fki:2S, 5fki:2U, 5fki:2W, 5fki:2Y, 5fki:20, 5fki:22, 5fki:24, 5fki:26, 5fki:28, 5fki:3A, 5fki:3C, 5fki:3E, 5fki:3G, 5fki:3I, 5fki:3K, 4z3u:D
18 3gg2:A 431 153 0.0499 0.0998 0.2810 6.1 3gg2:D, 3gg2:B, 3gg2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218