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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HYTFPKVWANSGTTADWQYVRRADNWQNNGFVDNVNSQQIRCFQSTHSPAQSTLSVAAGTTITYGAAPSVYHPGPMQFYL
ARVPDGQDINSWTGEGAVWFKIYHEQPTFGSQLTWSSNGKSSFPVKIPSCIKSGSYLLRAEHIGLHVAQSSGAAQFYISC
AQLSITGGGSTEPGANYKVSFPGAYKASDPGILININYPVPTSYKNPGPSVFTC

The query sequence (length=214) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4qi8:A 214 214 1.0000 1.0000 1.0000 1.37e-160 4qi8:B
2 3eii:A 208 214 0.7290 0.7500 0.7290 1.35e-111 3eii:B, 3eii:C, 3eii:D, 3eja:A, 3eja:B, 3eja:C, 3eja:D
3 8b7p:AAA 213 216 0.4720 0.4742 0.4676 1.28e-61 8b7p:BBB, 8b7p:CCC, 8b7p:DDD
4 7exk:A 217 218 0.4252 0.4194 0.4174 2.40e-47 7exk:B, 7exk:C, 7exk:D, 7exk:E, 7exk:F
5 4b5q:A 217 221 0.4626 0.4562 0.4480 7.69e-46 4b5q:B
6 4eir:A 223 206 0.3972 0.3812 0.4126 8.57e-36 4eir:B, 7t5c:A, 7t5c:B, 7t5d:A, 7t5d:B, 7t5e:A, 7t5e:B, 5tkf:A, 5tkf:C, 5tkf:B, 5tkf:D, 5tkg:A, 5tkg:B, 5tkh:A, 5tkh:B, 5tki:A, 5tki:B
7 4d7u:A 227 240 0.4252 0.4009 0.3792 8.29e-33 4d7u:B, 4d7v:A, 4d7v:B
8 5foh:A 218 228 0.4019 0.3945 0.3772 6.61e-32
9 4eis:A 225 202 0.3785 0.3600 0.4010 5.91e-31 4eis:B
10 6rs6:A 221 207 0.3598 0.3484 0.3720 2.21e-28 6rs9:A
11 5ufv:A 228 202 0.3411 0.3202 0.3614 4.59e-25 5ufv:B, 5ufv:C, 5ufv:D, 5ufv:E, 5ufv:F
12 5nns:A 225 170 0.2897 0.2756 0.3647 1.02e-21 5nns:B
13 5o2w:A 248 195 0.3224 0.2782 0.3538 1.05e-19 5o2x:A
14 8b4g:AAA 228 193 0.3178 0.2982 0.3523 2.03e-17 7pu1:AAA, 7pu1:BBB, 7pz3:A, 7pz4:A, 7pz5:A, 7pz6:A, 7pz7:A, 7pz8:A, 7q1k:A, 2yet:A, 2yet:B, 3zud:A
15 7ova:DDD 231 193 0.3037 0.2814 0.3368 3.09e-17 7ova:AAA, 7ova:BBB, 7ova:CCC
16 5acf:A 235 228 0.3458 0.3149 0.3246 4.35e-17 5acg:A, 5ach:A, 5aci:A, 5acj:A, 8e1w:A, 5n04:A, 5n05:A, 7nim:A, 7nin:A, 5nkw:A, 5nln:A, 5nlo:A, 5nlp:A, 5nlq:A, 5nlr:A, 5nls:A, 7pqr:A, 7ptz:AAA, 7pxi:A, 7pxj:A, 7pxk:A, 7pxl:A, 7pxm:A, 7pxn:A, 7pxr:A, 7pxs:A, 7pxt:A, 7pxu:A, 7pxv:A, 7pxw:A, 7pyd:A, 7pye:A, 7pyf:A, 7pyg:A, 7pyh:A, 7pyi:A, 7pyl:A, 7pym:A, 7pyn:A, 7pyo:A, 7pyp:A, 7pyq:A, 7pyu:A, 7pyw:A, 7pyx:A, 7pyy:A, 7pyz:A, 7pz0:A, 6ydg:A
17 7ntl:A 220 192 0.2991 0.2909 0.3333 1.61e-16
18 2vtc:A 228 191 0.2664 0.2500 0.2984 5.23e-14 2vtc:B
19 5nlt:B 227 237 0.3178 0.2996 0.2869 1.60e-13 5nlt:A, 5nlt:C, 5nlt:D, 5nlt:E, 5nlt:F, 6ydc:A, 6ydc:B, 6ydc:C, 6ydc:D, 6ydd:A, 6ydd:B, 6yde:A, 6ydf:A, 6ydf:B
20 7a8v:A 230 106 0.1963 0.1826 0.3962 2.90e-13
21 5x6a:A 229 193 0.2897 0.2707 0.3212 5.39e-13 6h1z:A, 6h1z:B, 6ha5:A, 6ha5:B, 6haq:A, 6haq:B, 5x6a:B
22 7vfc:A 228 195 0.2991 0.2807 0.3282 5.60e-12
23 6rxt:UQ 789 45 0.0701 0.0190 0.3333 2.1 6rxu:UQ, 6rxv:UQ, 6rxx:UQ, 6rxy:UQ, 6rxz:UQ
24 5fks:A 731 97 0.1215 0.0356 0.2680 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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