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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
HYGITSPISLASPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDVSESKNLPPSVVATVGGKIF
TFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEFDGIEIDLVFARLAIQTI
SDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQ
LYPNAAASTLVHKFFLVFSKWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMV
EEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLERNEFITLAHVNP
QSFPGNYVSMWFLGIIFRDLTYDIQSFTDTVYRQANNINMLKEGMKIEATHVKKKQLHHYLP

The query sequence (length=462) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 4lt6:A 467 462 1.0000 0.9893 1.0000 0.0 4lt6:B
2 1q78:A 470 470 0.7987 0.7851 0.7851 0.0 1f5a:A, 1q79:A
3 7q72:B 502 407 0.4069 0.3745 0.4619 4.87e-136
4 3c66:A 529 409 0.4048 0.3535 0.4572 6.57e-133 3c66:B, 1fa0:A, 1fa0:B, 2q66:A
5 8opp:A 670 77 0.0498 0.0343 0.2987 0.021
6 2q3o:B 367 116 0.0693 0.0872 0.2759 0.042 2g5w:A, 2g5w:B, 2q3o:A, 1q45:A, 1q45:B
7 5w0n:A 379 83 0.0498 0.0607 0.2771 0.15 5w0m:A, 5w0m:C, 5w0n:B
8 5w0b:A 334 83 0.0498 0.0689 0.2771 0.19
9 8opt:A 783 78 0.0455 0.0268 0.2692 0.29 8ops:A, 5w0m:B, 5w0n:C, 5w0o:A, 5w0o:B
10 7cgm:A 349 84 0.0498 0.0659 0.2738 0.51 7cgf:A, 7cgg:A, 7cgh:A, 7cgi:A, 7cgj:A, 7cgk:A, 7cgl:A, 6nod:A, 6nod:B, 6nod:C
11 7sn8:I 634 194 0.1017 0.0741 0.2423 0.52
12 5dy2:A 378 55 0.0455 0.0556 0.3818 0.53 5dxx:A, 5dxy:A, 5dy3:A
13 6ww7:A 927 65 0.0455 0.0227 0.3231 1.2
14 6mtp:H 218 29 0.0260 0.0550 0.4138 4.1 6mtp:A
15 6qvm:A 658 65 0.0433 0.0304 0.3077 4.2
16 6mxv:B 251 75 0.0476 0.0876 0.2933 4.8
17 6avh:B 541 49 0.0303 0.0259 0.2857 5.0
18 5kod:D 566 94 0.0584 0.0477 0.2872 5.0
19 8etf:C 330 56 0.0476 0.0667 0.3929 5.2 8esg:A, 8esg:H, 8etf:H, 8etf:A, 8etf:B, 8etf:D, 8etf:E, 8etf:F, 8etf:G, 8fao:H, 8fao:A, 8fao:B, 8fao:C, 8fao:D, 8fao:E, 8fao:F, 8fao:G
20 4abt:A 286 38 0.0346 0.0559 0.4211 6.0 4abt:B, 1fiu:A, 1fiu:B, 1fiu:D, 1fiu:C
21 1icp:A 358 62 0.0433 0.0559 0.3226 6.6 3hgr:A, 3hgr:B, 1icp:B, 1icq:A, 1icq:B, 1ics:A, 1ics:B
22 6e1q:A 569 52 0.0325 0.0264 0.2885 8.8 6avh:A, 6avh:C, 6avh:D
23 7vka:A 595 99 0.0563 0.0437 0.2626 9.4 5kod:A, 5kod:B, 5kod:C, 7vka:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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