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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HTRTLGFILPDLENPSYARIAKQLEQGARARGYQLLIASSDDQPDSERQLQQLFRARRCDALFVASCLPPEDDSYRELQD
KGLPVIAIDRRLDPAHFCSVISDDRDASRQLAASLLSSAPRSIALIGARPELSVSQARAGGFDEALQGYTGEVRRYQGEA
FSRECGQRLMQQLIDDLGGLPDALVTTSYVLLQGVFDTLQARPVDSRQLQLGTFGDNQLLDFLPLPVNAMAQQHGQIAAT
ALELALAAIEEKRYEPGVHAVGRTFKQRIS

The query sequence (length=270) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3o75:A 270 270 1.0000 1.0000 1.0000 0.0 3o75:B
2 7x7h:A 267 268 0.4370 0.4419 0.4403 1.04e-67 7x7h:C
3 8jff:A 274 272 0.4259 0.4197 0.4228 1.88e-64 8jff:B, 8jfv:A, 8jfv:B
4 2ioy:A 274 182 0.1667 0.1642 0.2473 2.83e-13 2ioy:B
5 3k4h:A 282 259 0.2370 0.2270 0.2471 4.53e-11 3k4h:B
6 3ctp:A 266 251 0.1852 0.1880 0.1992 9.99e-11 3ctp:B
7 1rzr:G 332 247 0.2185 0.1777 0.2389 4.18e-10 2jcg:A, 2nzu:G, 2nzv:G, 1rzr:C, 1rzr:A, 1rzr:D, 1sxg:B, 1zvv:A, 1zvv:B, 1zvv:G
8 1jft:A 340 264 0.2185 0.1735 0.2235 3.90e-08 1bdh:A, 1bdi:A, 1jfs:A, 1jh9:A, 1pnr:A, 2pua:A, 2pub:A, 2puc:A, 2pud:A, 2pue:A, 2puf:A, 2pug:A, 1qp0:A, 1qp4:A, 1qp7:A, 1qpz:A, 1qqa:A, 1qqb:A, 1vpw:A, 1wet:A, 1zay:A
9 4rk5:A 275 249 0.2148 0.2109 0.2329 4.36e-08 4rk4:A
10 4rk0:D 269 246 0.2148 0.2156 0.2358 4.71e-08 4rk0:A, 4rk0:B, 4rk0:C
11 4rk1:D 269 263 0.2074 0.2082 0.2129 4.80e-08 4rk1:A, 4rk1:B, 4rk1:C, 4rk1:E, 4rk1:F
12 2o20:B 275 179 0.1667 0.1636 0.2514 6.93e-08 2o20:A, 2o20:F, 2o20:G
13 1dbp:A 271 247 0.2074 0.2066 0.2267 4.67e-07 1drj:A, 1drk:A, 2dri:A, 2gx6:A
14 4rk6:A 270 147 0.1296 0.1296 0.2381 3.81e-06 4rk6:B, 4rk7:A, 4rk7:B
15 2vk2:A 296 158 0.1519 0.1385 0.2595 1.14e-05
16 4zjp:A 270 183 0.1481 0.1481 0.2186 4.16e-05
17 3tb6:A 283 120 0.1037 0.0989 0.2333 3.53e-04 3tb6:B
18 3oqo:A 333 86 0.0741 0.0601 0.2326 0.001 3oqm:A, 3oqm:C, 3oqn:A, 3oqn:C, 3oqo:C
19 5ibq:A 287 152 0.1111 0.1045 0.1974 0.016 4ry0:A
20 5dte:B 287 162 0.1296 0.1220 0.2160 0.046 5dte:A, 5dte:C, 5dte:D
21 7e7m:C 284 149 0.1259 0.1197 0.2282 0.083 7e7m:A, 7e7m:B, 7e7m:D
22 2a5j:A 177 106 0.1037 0.1582 0.2642 0.41 1z0a:A, 1z0a:B, 1z0a:D
23 7cih:C 311 33 0.0593 0.0514 0.4848 0.62 7ci0:A, 7ci0:B, 7ci0:C, 7ci0:D, 7cih:A, 7cih:B, 7cih:D, 7cip:A, 7cip:B, 7cip:C, 7cip:D, 6keu:A, 6keu:B, 6keu:C, 6keu:D, 6kf1:A, 6kf1:B, 6kf1:C, 6kf1:D, 6kf5:A, 6kf5:B, 6kf5:C, 6kf5:D, 6kf7:A, 6kf7:B, 6kf7:C, 6kf7:D, 7w8n:A, 7w8n:B, 7w8n:C, 7w8n:D
24 4rke:A 176 106 0.0963 0.1477 0.2453 0.78 1z0a:C
25 2fn8:A 292 93 0.0778 0.0719 0.2258 1.2
26 2w8s:B 513 96 0.0889 0.0468 0.2500 1.5 2w8s:A, 2w8s:C, 2w8s:D
27 2h3p:A 599 49 0.0741 0.0334 0.4082 1.9 2h3p:B, 2h3u:A, 2h3u:B, 2h3w:A, 2h3w:B, 1ndf:A, 1ndf:B, 1ndi:A, 1ndi:B, 1s5o:A, 1t7o:A, 1t7q:A, 1t7q:B
28 6njo:D 413 64 0.0667 0.0436 0.2812 2.9 6njo:B, 6njo:A, 6njo:C, 6njo:E, 6njp:B, 6njp:C, 6njp:D, 6njp:E, 2obl:A, 2obm:A
29 1gud:A 288 179 0.1407 0.1319 0.2123 3.1 1rpj:A, 8wl7:A, 8wl9:A, 8wlb:A
30 4rkr:A 274 34 0.0370 0.0365 0.2941 3.4 4rkr:B, 4rkr:C, 4rkr:D
31 5hr7:A 360 74 0.0852 0.0639 0.3108 4.5 5hr6:A, 5hr6:B, 5hr7:B, 4pl1:B, 4pl1:A, 4pl2:B, 4pl2:A, 3rf9:A, 3rf9:B, 3rfa:A, 3rfa:B
32 2x7x:A 301 90 0.0815 0.0731 0.2444 4.8 2x7x:B
33 5f3y:A 549 49 0.0667 0.0328 0.3673 5.0
34 6gt9:A 283 149 0.1148 0.1095 0.2081 6.5 6gt9:B, 6gt9:C, 6gt9:D, 6guq:A
35 4m25:B 317 63 0.0778 0.0662 0.3333 8.8 4m25:C, 4m25:D, 4m26:B, 4m27:B, 4m2f:B, 4m2g:B, 4m2i:B, 4m2i:C, 4m2i:D, 4ne0:B, 4ne0:D
36 3m1r:D 321 144 0.1593 0.1340 0.2986 8.9 3m1r:A, 3m1r:B, 3m1r:C, 3m1r:E, 3m1r:F
37 4adb:B 401 40 0.0556 0.0374 0.3750 9.7 4adb:A, 4adb:C, 4adb:D, 4adc:A, 4adc:B, 4adc:C, 4adc:D, 4add:A, 4add:B, 4add:C, 4add:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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