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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HTPEEALALLKRGAEEIVPEEELLAKLKEGRPLTVKLGADPTRPDLHLGHAVVLRKMRQFQELGHKVVLIIGDFTGMIGD
PSGRSKTRPPLTLEETRENAKTYVAQAGKILRQEPHLFELRYNSEWLEGLTFKEVVRLTSLMTVAQMLEREDFKKRYEAG
IPISLHELLYPFAQAYDSVAIRADVEMGGTDQRFNLLVGREVQRAYGQSPQVCFLMPLLVGLDGREKMSKSLDNYIGLTE
PPEAMFKKLMRVPDPLLPSYFRLLTDLEEEEIEALLKAGPVPAHRVLARLLTAAYALPQIPPRIDRAFYESLGYAWEAFG
RDKEAGPEEVRRAEARYDEVAKGGIPEEIPEVTIPASELKEGRIWVARLFTLAGLTPSNAEARRLIQNRGLRLDGEVLTD
PMLQVDLSRPRILQRGKDRFVRVRLSD

The query sequence (length=427) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h3e:A 427 427 1.0000 1.0000 1.0000 0.0
2 1h3f:B 406 427 0.9485 0.9975 0.9485 0.0 1h3f:A
3 6bqz:A 215 220 0.2834 0.5628 0.5500 3.42e-83 6bqz:B
4 1jil:A 323 265 0.1967 0.2601 0.3170 1.28e-27 1jii:A, 1jij:A, 1jik:A
5 6otj:B 431 414 0.2670 0.2645 0.2754 1.93e-27 6otj:A
6 6hb5:B 417 442 0.2717 0.2782 0.2624 6.36e-27 7ap3:A, 7ap3:B, 6hb5:A, 6hb6:A, 6hb6:B, 6hb7:A, 6hb7:B, 6i5y:A, 6i5y:B, 4oud:A, 1vbm:A, 1vbm:B, 1vbn:A, 1vbn:B, 6wn2:A, 6wn2:B, 1wq3:A, 1wq4:A, 1x8x:A, 2yxn:A
7 3ts1:A 317 280 0.2014 0.2713 0.3071 1.32e-25 4ts1:A, 4ts1:B, 1tya:E, 1tyb:E, 1tyd:E
8 2cyb:A 319 256 0.1756 0.2351 0.2930 3.49e-22 2cyb:B
9 5ihx:A 360 316 0.1780 0.2111 0.2405 6.40e-18
10 4ojm:X 382 284 0.1756 0.1963 0.2641 4.68e-17 2rkj:B, 2rkj:F, 2rkj:J, 2rkj:N, 1y42:X
11 2pid:B 324 271 0.1663 0.2191 0.2620 1.37e-16 2pid:A, 3zxi:A, 3zxi:B
12 5ijx:A 365 202 0.1335 0.1562 0.2822 8.23e-15
13 4nx2:A 313 260 0.1663 0.2268 0.2731 8.16e-14 2ag6:A, 7ckg:B, 3d6u:A, 3d6v:A, 2hgz:A, 4hjx:A, 4hjx:B, 4hpw:A, 1j1u:A, 5l7p:B, 3n2y:A, 3n2y:B, 5n5u:A, 4nda:A, 5nsf:B, 5nsf:A, 5nsf:C, 5nsf:D, 4pbr:A, 4pbs:A, 4pbt:A, 2pxh:A, 3qe4:A, 3qe4:B, 6wrk:A, 6wrn:A, 6wrq:A, 6wrt:A, 7ynw:A, 7ynw:B, 1zh0:A, 1zh6:A, 2zp1:A
14 7rou:A 335 244 0.1616 0.2060 0.2828 6.06e-10 1q11:A, 4q93:A, 4qbt:A, 5thh:A
15 2dlc:X 339 257 0.1429 0.1799 0.2374 1.62e-06
16 2a4m:C 331 129 0.0960 0.1239 0.3178 1.98e-05 1yi8:C, 1yia:B, 1yid:B
17 2cyc:A 371 243 0.1358 0.1563 0.2387 3.01e-05 2cyc:B
18 2g36:A 322 231 0.1452 0.1925 0.2684 1.70e-04
19 5tew:A 333 265 0.1522 0.1952 0.2453 0.001
20 5usf:A 682 333 0.1756 0.1100 0.2252 0.001 3p0h:A, 3p0i:A, 3p0j:C, 3p0j:D, 5usf:B
21 7sc6:A 349 237 0.1218 0.1490 0.2194 0.002 7scq:A, 7scq:B
22 3p0j:A 657 163 0.1030 0.0670 0.2699 0.003 3p0h:B, 3p0i:B, 3p0j:B
23 6dfu:A 332 121 0.0773 0.0994 0.2727 0.012 6dfu:B
24 8i1w:B 333 126 0.0796 0.1021 0.2698 0.015 8i1y:A, 8i1y:B, 8i1z:A, 8i1z:B, 8i27:A, 8i27:B, 8i2a:B, 8i2a:A, 8i2c:A, 8i2c:B, 8i2j:A, 8i2j:B, 8i2l:B, 8i2l:A, 8i2m:A, 8i2m:B, 8i4i:A, 8i4i:B, 5v0i:A, 5v0i:B
25 6ncr:A 342 95 0.0656 0.0819 0.2947 0.083 6ncr:B
26 3a04:A 367 244 0.1405 0.1635 0.2459 0.094 3a05:A
27 7ror:B 362 80 0.0585 0.0691 0.3125 0.27 7ror:A, 7ros:A, 7ros:B, 7rot:A, 7rot:B, 3vgj:A, 3vgj:B
28 3hv0:A 352 144 0.0867 0.1051 0.2569 2.0 3hv0:B
29 8rxh:LY 133 104 0.0656 0.2105 0.2692 2.9 8a3w:Y, 8a98:Y, 6az3:Y, 3jcs:Y, 8ovj:Y, 8rxx:LY, 5t2a:Y
30 3fhj:D 286 232 0.1335 0.1993 0.2457 3.1 3fhj:C
31 3kt8:D 410 126 0.0703 0.0732 0.2381 3.5 3kt0:A, 3kt3:A, 3kt3:B, 3kt3:C, 3kt3:D, 3kt6:A, 3kt6:B, 3kt6:C, 3kt6:D, 3kt8:A, 3kt8:B, 3kt8:C
32 1v5n:A 89 48 0.0398 0.1910 0.3542 5.6
33 7cms:A 328 125 0.0656 0.0854 0.2240 5.7 7cki:A, 7cms:B, 5dk4:A, 7eer:A, 7eer:B, 7eer:C, 7eer:D, 1i6k:A, 1i6l:A, 1i6m:A, 1m83:A, 1mau:A, 1maw:A, 1maw:B, 1maw:C, 1maw:D, 1maw:E, 1maw:F, 1mb2:A, 1mb2:B, 1mb2:C, 1mb2:D, 1mb2:E, 1mb2:F, 2ov4:A
34 5oeu:C 412 129 0.0656 0.0680 0.2171 7.6
35 8x6f:C 1153 70 0.0515 0.0191 0.3143 8.0
36 2cul:A 225 119 0.0820 0.1556 0.2941 8.1
37 4a35:A 441 55 0.0375 0.0363 0.2909 8.3
38 7w54:B 518 47 0.0375 0.0309 0.3404 9.2 7w54:A
39 5oeu:A 460 130 0.0703 0.0652 0.2308 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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