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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HTIFSSLEVNGVNQGLGEGVRVPTYNGPIEDVTSASIACNGSPNTVASTSKVITVQAGTNVTAIWRYMLSTTGDSPADVM
DSSHKGPTIAYLKKVDNAATASGVGNGWFKIQQDGMDSSGVWGTERVINGKGRHSIKIPECIAPGQYLLRAEMIALHAAS
NYPGAQFYMECAQLNVVGGTGAKTPSTVSFPGAYSGSDPGVKISIYWPPVTAYTVPGPSVFTC

The query sequence (length=223) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4eir:A 223 223 1.0000 1.0000 1.0000 2.23e-166 4eir:B, 7t5c:A, 7t5c:B, 7t5d:A, 7t5d:B, 7t5e:A, 7t5e:B, 5tkf:A, 5tkf:C, 5tkf:B, 5tkf:D, 5tkg:A, 5tkg:B, 5tkh:A, 5tkh:B, 5tki:A, 5tki:B
2 5foh:A 218 223 0.5740 0.5872 0.5740 4.60e-85
3 4d7u:A 227 231 0.4843 0.4758 0.4675 3.51e-63 4d7u:B, 4d7v:A, 4d7v:B
4 6rs6:A 221 226 0.4484 0.4525 0.4425 6.36e-56 6rs9:A
5 5acf:A 235 232 0.3901 0.3702 0.3750 2.48e-42 5acg:A, 5ach:A, 5aci:A, 5acj:A, 8e1w:A, 5n04:A, 5n05:A, 7nim:A, 7nin:A, 5nkw:A, 5nln:A, 5nlo:A, 5nlp:A, 5nlq:A, 5nlr:A, 5nls:A, 7pqr:A, 7ptz:AAA, 7pxi:A, 7pxj:A, 7pxk:A, 7pxl:A, 7pxm:A, 7pxn:A, 7pxr:A, 7pxs:A, 7pxt:A, 7pxu:A, 7pxv:A, 7pxw:A, 7pyd:A, 7pye:A, 7pyf:A, 7pyg:A, 7pyh:A, 7pyi:A, 7pyl:A, 7pym:A, 7pyn:A, 7pyo:A, 7pyp:A, 7pyq:A, 7pyu:A, 7pyw:A, 7pyx:A, 7pyy:A, 7pyz:A, 7pz0:A, 6ydg:A
6 4eis:A 225 205 0.3812 0.3778 0.4146 3.26e-42 4eis:B
7 8b7p:AAA 213 229 0.3857 0.4038 0.3755 5.31e-40 8b7p:BBB, 8b7p:CCC, 8b7p:DDD
8 3eii:A 208 203 0.3587 0.3846 0.3941 1.67e-36 3eii:B, 3eii:C, 3eii:D, 3eja:A, 3eja:B, 3eja:C, 3eja:D
9 4qi8:A 214 206 0.3812 0.3972 0.4126 8.93e-36 4qi8:B
10 5nns:A 225 206 0.3901 0.3867 0.4223 1.70e-35 5nns:B
11 5nlt:B 227 234 0.3543 0.3480 0.3376 5.02e-33 5nlt:A, 5nlt:C, 5nlt:D, 5nlt:E, 5nlt:F, 6ydc:A, 6ydc:B, 6ydc:C, 6ydc:D, 6ydd:A, 6ydd:B, 6yde:A, 6ydf:A, 6ydf:B
12 7exk:A 217 204 0.3543 0.3641 0.3873 2.85e-28 7exk:B, 7exk:C, 7exk:D, 7exk:E, 7exk:F
13 4b5q:A 217 204 0.3274 0.3364 0.3578 9.03e-25 4b5q:B
14 8b4g:AAA 228 146 0.2422 0.2368 0.3699 1.11e-24 7pu1:AAA, 7pu1:BBB, 7pz3:A, 7pz4:A, 7pz5:A, 7pz6:A, 7pz7:A, 7pz8:A, 7q1k:A, 2yet:A, 2yet:B, 3zud:A
15 7a8v:A 230 145 0.2332 0.2261 0.3586 1.05e-23
16 7ntl:A 220 172 0.2601 0.2636 0.3372 3.68e-23
17 5x6a:A 229 145 0.2377 0.2314 0.3655 6.96e-22 6h1z:A, 6h1z:B, 6ha5:A, 6ha5:B, 6haq:A, 6haq:B, 5x6a:B
18 5ufv:A 228 219 0.3004 0.2939 0.3059 1.25e-21 5ufv:B, 5ufv:C, 5ufv:D, 5ufv:E, 5ufv:F
19 7ova:DDD 231 145 0.2152 0.2078 0.3310 2.26e-21 7ova:AAA, 7ova:BBB, 7ova:CCC
20 7vfc:A 228 196 0.2960 0.2895 0.3367 4.02e-21
21 5o2w:A 248 143 0.2422 0.2177 0.3776 4.45e-21 5o2x:A
22 2vtc:A 228 196 0.2511 0.2456 0.2857 6.06e-19 2vtc:B
23 6jzb:A 251 31 0.0628 0.0558 0.4516 2.2
24 6zu5:SG0 218 52 0.0448 0.0459 0.1923 2.4
25 4tqm:A 402 58 0.0762 0.0423 0.2931 2.9
26 2n2h:B 125 47 0.0717 0.1280 0.3404 6.9
27 6tmh:B 479 58 0.0807 0.0376 0.3103 7.7 6tmh:D, 6tmk:B2, 6tmk:D2, 6tmk:B1, 6tmk:D1
28 8rpl:B 630 95 0.1166 0.0413 0.2737 9.7 8rpk:A, 8rpk:B, 8rpk:C, 8rpk:D, 8rpl:A, 8rpl:C, 8rpl:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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