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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HTARLIHTSDLDQETRDGARRMVIEAFRTDDFTDDDWDHALGGMHALISHHGALIAHGAVVQRRLMYRGPDGRGHALRCG
YVEAVAVREDRRGDGLGTAVLDALEQVIRGAYQIGALSASDIARPMYIARGWLSWEGPTSVLTPTEGIVRTPEDDRSLFV
LPVDLPDGLELDTAREITCDWRSGDPW

The query sequence (length=187) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cs1:A 191 190 1.0000 0.9791 0.9842 4.88e-132 7cs0:A, 7cs0:B, 7cs1:B, 7csi:A, 7csi:B, 7csj:A, 7csj:B
2 1m4d:A 181 187 0.6417 0.6630 0.6417 1.35e-77 1m4d:B, 1m4g:A, 1m4g:B, 1m4i:A, 1m4i:B
3 5us1:A 189 184 0.3102 0.3069 0.3152 2.50e-26 7jzs:A, 5us1:B, 5us1:C, 5us1:D, 5us1:E, 5us1:F, 5us1:G, 5us1:H, 5us1:I, 5us1:K, 5us1:L, 6vou:A, 6vou:B, 6vr2:A, 6vr2:B, 6vr3:A, 6vr3:B, 6vta:A, 6vta:B
4 3mgd:B 154 57 0.1070 0.1299 0.3509 0.024 3mgd:A
5 5fbt:A 769 58 0.0909 0.0221 0.2931 0.074
6 5fbs:A 787 58 0.0909 0.0216 0.2931 0.074
7 5hv1:A 847 58 0.0909 0.0201 0.2931 0.085 5hv3:A
8 5fbu:A 733 58 0.0909 0.0232 0.2931 0.086
9 5kf2:A 317 85 0.1176 0.0694 0.2588 0.18 5kf1:A, 5kf1:B, 5kf8:A, 5kf9:A, 5kga:A, 5kga:B, 5kgh:A, 5kgh:B, 5kgj:A, 5kgp:A, 5kgp:B
10 1qnf:A 475 104 0.1497 0.0589 0.2692 0.48 1owl:A, 1owm:A, 1own:A, 1owo:A, 1owp:A, 1tez:A, 1tez:B, 1tez:C, 1tez:D
11 1i1d:D 161 26 0.0588 0.0683 0.4231 1.00 1i12:A, 1i12:B, 1i12:C, 1i12:D, 1i1d:A, 1i1d:B, 1i1d:C
12 5jph:B 144 47 0.0749 0.0972 0.2979 1.0 5jph:A, 5jph:C
13 2fiw:A 160 71 0.1176 0.1375 0.3099 1.5
14 1lhs:A 153 79 0.1123 0.1373 0.2658 2.1 1lht:A
15 3f5b:A 172 48 0.0642 0.0698 0.2500 2.1
16 6tdf:A 165 86 0.1283 0.1455 0.2791 2.4 6tdg:A, 6tdh:A, 2vez:A, 2vxk:A
17 5k3w:A 298 35 0.0642 0.0403 0.3429 2.7 5k3w:B
18 2q0y:A 153 54 0.0749 0.0915 0.2593 3.1
19 4ypo:A 325 62 0.1283 0.0738 0.3871 3.3 4ypo:B
20 7zkt:B 202 26 0.0642 0.0594 0.4615 3.6 7zhc:A, 7zhc:B, 7zkt:A, 7zkt:C, 7zkt:D, 7zkt:E, 7zkt:F, 7zkt:G, 7zkt:H
21 2r6r:1 323 52 0.0856 0.0495 0.3077 3.7 2r75:1
22 5wje:A 159 64 0.0802 0.0943 0.2344 3.7 5wjd:A
23 7l1k:A 149 59 0.1016 0.1275 0.3220 4.1
24 5c88:A 158 37 0.0642 0.0759 0.3243 4.3 6ag4:A, 6ag5:A, 5c88:B, 4lx9:A, 4r3k:A, 4r3l:A, 2x7b:A
25 2b4b:B 170 27 0.0642 0.0706 0.4444 4.4 2b3v:A, 2b4b:A, 2b4d:A, 2b4d:B, 2b58:A, 3bj7:A, 3bj7:B, 3bj7:C, 3bj7:D, 3bj8:A, 3bj8:B, 3bj8:C, 3bj8:D, 2fxf:A, 2fxf:B, 2jev:A, 2jev:B
26 2j8m:A 171 26 0.0802 0.0877 0.5769 5.6 2bl1:A, 2j8m:B, 2j8r:A, 2j8r:B
27 4um9:D 455 46 0.0802 0.0330 0.3261 7.3 5ffg:B, 5ffo:B, 5ffo:F, 5neu:B, 8tcg:B, 4um8:B, 4um8:D, 4um9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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