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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQ
PPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIK
FLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE

The query sequence (length=222) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hyj:B 223 220 0.9865 0.9821 0.9955 1.93e-164 6hyj:A, 6hyy:A, 6hyy:B, 1l8l:A, 1l8l:B, 1l8o:A, 1l8o:B, 1nnl:A, 1nnl:B, 6q6j:A, 6q6j:B
2 6iuy:A 585 221 0.3829 0.1453 0.3846 2.06e-44 6iuy:B
3 3kd3:A 216 212 0.2703 0.2778 0.2830 7.21e-21 3kd3:B
4 1f5s:A 210 194 0.2748 0.2905 0.3144 4.19e-20 1f5s:B, 1j97:A, 1j97:B, 1l7m:A, 1l7m:B, 1l7n:A, 1l7n:B, 1l7o:A, 1l7o:B, 1l7p:A, 1l7p:B
5 3m1y:C 208 188 0.2658 0.2837 0.3138 2.11e-16 3m1y:A, 3m1y:B, 3m1y:D
6 8q4s:A 295 169 0.2568 0.1932 0.3373 4.13e-14 7qpl:A
7 8a1z:A 396 212 0.2748 0.1540 0.2877 2.37e-12 8a21:A, 5is2:A, 5it0:A, 5it4:A, 5jjb:A, 5jlp:A, 5jlr:A, 5jma:A, 3p96:A, 5t41:A
8 4ap9:A 200 189 0.2207 0.2450 0.2593 1.73e-08 4ap9:B, 4ap9:C, 4ap9:D
9 2fea:A 225 212 0.2162 0.2133 0.2264 1.88e-04 2fea:B
10 4fe3:A 291 116 0.1171 0.0893 0.2241 0.008 2g06:A, 2g06:B, 2g07:A, 2g07:B, 2g08:A, 2g08:B, 2g09:A, 2g09:B, 2g0a:A, 2g0a:B, 2jga:A, 4kx3:A, 4kx5:A, 2vkq:A
11 4as2:A 327 91 0.1126 0.0765 0.2747 0.032 4as2:B, 4as2:C, 4as2:D, 4as3:A, 4as3:B, 4as3:C, 4as3:D
12 5v0t:E 457 107 0.1306 0.0635 0.2710 0.19 5v0t:A, 5v0t:B, 5v0t:C, 5v0t:D, 5v0t:F, 5v0t:G, 5v0t:H
13 8ioy:A 816 103 0.1306 0.0355 0.2816 0.37
14 3sky:A 261 112 0.1216 0.1034 0.2411 0.96
15 8snb:6R 72 26 0.0586 0.1806 0.5000 1.3
16 1nf2:A 267 29 0.0541 0.0449 0.4138 1.3 1nf2:B, 1nf2:C
17 3pco:C 323 112 0.1532 0.1053 0.3036 2.5 6oz5:A, 6oz5:C, 6p24:A, 6p26:A, 6p26:C, 3pco:A
18 1te2:A 218 62 0.0901 0.0917 0.3226 3.2 1te2:B
19 7c2x:A 490 30 0.0631 0.0286 0.4667 3.5
20 7si6:A 873 103 0.1216 0.0309 0.2621 3.7 7si3:A, 7si7:A
21 4u99:A 187 28 0.0586 0.0695 0.4643 6.8 2kii:A, 2kil:A, 4u99:B, 4u9b:A, 4u9g:A, 4u9g:B, 4u9j:A, 4u9j:B, 4u9k:A, 4u9k:B
22 5c5e:A 284 50 0.0811 0.0634 0.3600 6.9 5c5e:B, 4g86:A, 4g86:B
23 8iwp:A 896 125 0.1351 0.0335 0.2400 8.1 8iwr:A, 8iws:A, 8iwt:A, 8iwu:A, 8iww:A, 7yag:A, 7yah:A, 7yai:A, 7yaj:A, 7yam:A
24 2yj4:B 252 120 0.1351 0.1190 0.2500 9.9 2iye:A, 2iye:C, 2yj3:A, 2yj4:A, 2yj5:A, 2yj5:B, 2yj6:A, 2yj6:B
25 5z9o:A 373 22 0.0450 0.0268 0.4545 9.9 5z9o:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218