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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HRFETFTEEPIRLIGEEGEWLGDFPLDLEGEKLRRLYRDMLAARMLDERYTILIRTGKTSFIAPAAGHEAAQVAIAHAIR
PGFDWVFPYYRDHGLALALGIPLKELLGQMLATKADPNKGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAISMKLLRT
GQVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFIAENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDGMDVLASYY
VVKEAVERARRGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRKKDPIPRFRRFLEARGLWNEEWEEDVREEIRAE
LERGLKEAEEAGPVPPEWMFEDVFAEKPWHLLRQEALLKEE

The query sequence (length=361) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1umb:A 362 361 1.0000 0.9972 1.0000 0.0 1umb:C, 1umc:A, 1umc:C, 1umd:A, 1umd:C
2 3duf:A 365 336 0.3934 0.3890 0.4226 2.55e-77 3duf:C, 3duf:E, 3duf:G, 3dv0:A, 3dv0:C, 3dv0:G, 3dva:A, 3dva:C, 3dva:E, 3dva:G, 1w85:A, 1w85:C, 1w85:E, 1w85:G
3 2bff:A 392 332 0.3546 0.3265 0.3855 1.52e-66 2beu:A, 2bev:A, 2bew:A, 2bfd:A, 2bfe:A, 1dtw:A, 2j9f:A, 2j9f:C, 1ols:A, 1olx:A, 1u5b:A, 1wci:A, 1x7z:A
4 3dv0:E 344 335 0.3629 0.3808 0.3910 2.34e-66 1w88:A, 1w88:C, 1w88:E, 1w88:G
5 1qs0:A 407 351 0.3490 0.3096 0.3590 5.15e-62
6 1v1m:A 372 331 0.3241 0.3145 0.3535 7.72e-56 2bfb:A, 2bfc:A, 1olu:A, 1v11:A, 1v16:A, 1x7w:A, 1x7x:A, 1x7y:A, 1x80:A
7 3exe:A 363 307 0.2659 0.2645 0.3127 2.40e-34 6cfo:A, 6cfo:C, 3exe:C, 3exe:E, 3exe:G, 3exf:A, 3exf:C, 3exf:E, 3exf:G, 3exh:A, 3exh:C, 3exh:G, 1ni4:C, 1ni4:A, 2ozl:A, 2ozl:C
8 6cer:A 342 307 0.2576 0.2719 0.3029 1.84e-28 6cer:C, 6cer:E, 6cer:G, 3exh:E
9 8p5v:A 1121 156 0.1247 0.0401 0.2885 8.77e-07 8p5t:A, 8p5t:B, 8p5t:C, 8p5t:D, 8p5t:E, 8p5t:F, 8p5u:A, 8p5u:B, 8p5u:C, 8p5u:D, 8p5u:E, 8p5u:F, 8p5v:B, 8p5v:E, 8p5v:D, 8p5v:C, 8p5v:F, 8p5w:A, 8p5w:B, 8p5w:C, 8p5w:D, 8p5w:E, 8p5w:F
10 8p5s:A 1087 157 0.1219 0.0405 0.2803 5.02e-06 8p5x:A, 8p5x:B, 8p5x:C, 8p5x:D, 8p5x:E, 8p5x:F
11 8p5r:C 1109 176 0.1163 0.0379 0.2386 5.45e-04 6i2q:A, 6i2r:A, 6i2r:C, 6i2s:A, 8p5r:A, 8p5r:B, 8p5r:D, 8p5r:E, 8p5r:F, 6r2b:A, 6r2b:D, 6r2c:A, 6r2c:B, 6r2c:C, 6r2c:D, 6r2d:A, 6r2d:B, 6r2d:C, 6r2d:D, 2xt6:A, 2xt6:B, 2xta:A, 2xta:B, 2xta:C, 2xta:D, 2y0p:D, 2yic:A, 2yic:B, 2yic:C, 2yic:D, 2yid:A, 2yid:B, 2yid:C, 2yid:D, 3zhq:A, 3zhq:B, 3zhq:C, 3zhq:D, 3zhr:A, 3zhr:B, 3zhr:C, 3zhr:D, 3zhs:A, 3zhs:B, 3zhs:C, 3zhs:D, 3zht:A, 3zht:B, 3zht:C, 3zht:D, 3zhu:A, 3zhu:B, 3zhu:C, 3zhu:D, 3zhv:A, 3zhv:B, 3zhv:C, 3zhv:D
12 2y0p:C 856 176 0.1163 0.0491 0.2386 5.69e-04 6r29:A, 6r29:B, 6r2a:A, 6r2a:B, 6r2b:B, 6r2b:C, 2y0p:A, 2y0p:B
13 6yak:AAA 282 130 0.0914 0.1170 0.2538 0.030 6yak:CCC
14 1zun:B 394 101 0.0859 0.0787 0.3069 1.4
15 3kd6:A 300 54 0.0499 0.0600 0.3333 2.3 3kd6:B
16 7tm7:A 802 62 0.0416 0.0187 0.2419 5.4 7tm7:B
17 8bzx:B 568 113 0.0803 0.0511 0.2566 7.0
18 6uv1:A 438 127 0.0803 0.0662 0.2283 8.7 6uv1:B, 6uv2:A, 6uv3:A, 6uv4:A
19 6bli:D 221 38 0.0416 0.0679 0.3947 8.8 6bli:G, 6bli:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218